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2,081 results
  • Individual differences in human opioid abuse potential as observed in a human laboratory study. [Journal Article]
    Drug Alcohol Depend 2019; 205:107688Dunn KE, Barrett FS, … Bigelow GE
  • CONCLUSIONS: Data suggest the abuse potential of opioids is significantly different between individuals but that the experience within an individual is highly consistent. Research to prospectively characterize and evaluate mechanisms underlying these differences is warranted and may provide a foundation to help identify persons at heightened risk of transitioning from opioid exposure to misuse and/or opioid use disorder.
  • Analgesic Use Following Bilateral Breast Reduction. [Journal Article]
    Ann Plast Surg 2019Fisher AH, Powelson IA, … Freed GL
  • The opioid epidemic in the United States resulted in 42,000 deaths in 2016, 40% of which involved a prescription opioid. It is estimated that 2 million patients become opioid-dependent after elective, ambulatory surgery each year. There has been increased interest in quantifying the need for postoperative narcotic pain medications for a variety of surgical procedures. However, studies have been l…
  • Sustained-release Oral Hydromorphone for the Treatment of Opioid Use Disorder. [Journal Article]
    J Addict Med 2019Braithwaite V, Fairgrieve C, Nolan S
  • CONCLUSIONS: The case presented offers promise for the use of once-daily sustained-release oral hydromorphone as a viable treatment option for patients with OUD for whom first-line therapies are not suitable or tolerated. This case report is the first to our knowledge to demonstrate the successful use of oral hydromorphone for treatment of opioid use disorder.
  • LiverTox: Clinical and Research Information on Drug-Induced Liver Injury: Hydromorphone [BOOK]
    National Institute of Diabetes and Digestive and Kidney Diseases: Bethesda (MD)BOOK
  • Hydromorphone and oxymorphone are semisynthetic derivatives of morphine and potent opiate agonists which are used predominantly to treat moderate-to-severe pain. Neither hydromorphone nor oxymorphone have been linked to serum enzyme elevations during therapy or to clinically apparent liver injury.
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