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(Heart Failure)
238,111 results
  • Causes and mechanisms of isolated mitral regurgitation in the community: clinical context and outcome. [Journal Article]
  • EHEur Heart J 2019 May 23
  • Dziadzko V, Dziadzko M, … Enriquez-Sarano M
  • CONCLUSIONS: Moderate/severe isolated MR in the community displays considerable aetiology/mechanism heterogeneity. Functional MR dominates, mostly FMR-v but FMR-a is frequent and degenerative MR dominates OMR. Outcomes are mediocre with excess-mortality particularly with FMR-v but FMR-a, despite normal EF incurs notable excess-mortality and frequent heart failure. Pervasive undertreatment warrants clinical trials of therapies tailored to specific MR cause/mechanisms.
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