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(Hemoglobinuria )
5,704 results
  • Clinical profile and outcome of pigment-induced nephropathy. [Journal Article]
  • CKClin Kidney J 2018; 11(3):348-352
  • Sakthirajan R, Dhanapriya J, … Abraham Kurien A
  • CONCLUSIONS: Pigment nephropathy due to rhabdomyolysis and hemolysis is an important cause of renal failure requiring HD. The prognosis was relatively good and depends on the etiology; however, long-term studies and follow-up are needed to assess the true incidence of CKD due to pigment nephropathy.
  • Prothrombotic mechanisms in patients with congenital p.Cys89Tyr mutation in CD59. [Journal Article]
  • TRThromb Res 2018 Jun 11; 168:67-77
  • Tabib A, Hindi I, … Mevorach D
  • CONCLUSIONS: Nonfunctioning CD59 is a major risk factor for stroke and hypercoagulability. Uncontrolled hemolysis causes massive MP release and endothelial heme damage. MAC attack on unprotected endothelium and platelet activation and aggregation with leukocytes mediate additional mechanisms leading to vascular occlusion. It is suggested that CD59 loss represents a major arterial prothrombotic factor in PNH and additional diseases.
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