- Hepatic and cardiac hemodynamics and systemic inflammation in cirrhosis: it takes three to tango. [Editorial]
- JHJ Hepatol 2018 Feb 17
- In this editorial the roles of systemic inflammation, elevated pressure in portal venous system and heart function and circulation in stable cirrhosis and decompensated cirrhosis with or without orga...
In this editorial the roles of systemic inflammation, elevated pressure in portal venous system and heart function and circulation in stable cirrhosis and decompensated cirrhosis with or without organ failures are described.
- Clinical and Prognostic Associations of Liver Volume determined by Computed Tomography in Acute Liver Failure. [Journal Article]
- LILiver Int 2018 Feb 20
- CONCLUSIONS: In patients with ALF/ALI LV shows marked variation by the cause of disease, and in prognostic importance. In indeterminate and DILI cases, loss of volume to <1000 cm3may indicate irreversible liver injury and regenerative failure and serve as an early clinical predictor of the development of high grade encephalopathy and death. This article is protected by copyright. All rights reserved.
- A Patient with Hemolytic Uremic Syndrome and Kidney Failure. [Journal Article]
- CJClin J Am Soc Nephrol 2018 Feb 19
- Acute-on-Chronic Liver Failure: A Portuguese Single-Center Reference Review. [Journal Article]
- GPGE Port J Gastroenterol 2018; 25(1):18-23
- CONCLUSIONS: ACLF is a heterogeneous syndrome with a variety of precipitant factors and different grades of extrahepatic involvement. Most cases will have some degree of renal dysfunction, with an increased risk of mortality. Hepatic transplant is an efficient form of therapy for this syndrome.
- Acute (Not Decompensation)-on-Chronic Liver Failure. [Editorial]
- GPGE Port J Gastroenterol 2018; 25(1):4-5
- Value of the albumin-bilirubin score in the evaluation of hepatitis B virus-related acute-on-chronic liver failure, liver cirrhosis, and hepatocellular carcinoma. [Journal Article]
- ETExp Ther Med 2018; 15(3):3074-3079
- The aim of the present study was to investigate the value of the albumin-bilirubin (ALBI) score in the assessment of the disease conditions of hepatitis B virus (HBV)-related acute-on-chronic liver f...
The aim of the present study was to investigate the value of the albumin-bilirubin (ALBI) score in the assessment of the disease conditions of hepatitis B virus (HBV)-related acute-on-chronic liver failure (HBV-ACLF), HBV-related liver cirrhosis (HBV-LC) and HBV-related hepatocellular carcinoma (HBV-HCC). A total of 395 patients with HBV-ACLF, HBV-LC, or HBV-HCC were retrospectively studied. The ALBI, Child-Turcotte-Pugh (CTP), and Model for End-Stage Liver Disease (MELD) scores of the patients were calculated, and the relationships between the ALBI score and the CTP and MELD scores were investigated. Furthermore, the ALBI grading was tested for the evaluation of the severity and stages of HBV-ACLF, HBV-LC, and HBV-HCC, especially when classifying the clinical stages of HBV-ACLF. The mean ALBI scores of the HBV-ACLF, HBV-LC, and HBV-HCC patients were -1.17±0.55, -1.76±0.66 and -2.59±0.62, respectively; the mean CTP scores were 10.70±1.81, 8.19±1.25 and 5.81±1.22, respectively; and the mean MELD scores were 19.93±7.44, 11.10±4.39 and 7.01±3.22, respectively. The ALBI scores were positively correlated with the CTP and MELD scores. The mean ALBI score and the frequency of grade 3 disease were higher in HBV-ACLF patients than in patients with HBV-LC or HBV-HCC. A later HBV-ACLF stage resulted in a higher frequency of ALBI grades of 3. In conclusion, ALBI scores exhibited parallel tendencies to the CTP and MELD scores in HBV-ACLF, HBV-LC, and HBV-HCC patients; thus, ALBI grading may be a simple but applicable method for the evaluation of the functional status of patients with HBV-related end-stage liver diseases.
- Gastroenteritis in an adult female revealing hemolytic uremic syndrome: Case report. [Journal Article]
- WJWorld J Gastroenterol 2018 Feb 14; 24(6):763-766
- Nowadays acute gastroenteritis infection caused byEscherichia coli(E. coli) O157:H7 is frequently associated with hemolytic uremic syndrome (HUS), which usually developed after prodromal diarrhea tha...
Nowadays acute gastroenteritis infection caused byEscherichia coli(E. coli) O157:H7 is frequently associated with hemolytic uremic syndrome (HUS), which usually developed after prodromal diarrhea that is often bloody. The abdominal pain accompanied by failure kidney is a suspicious symptom to develop this disorder. Their pathological characteristic is vascular damage which manifested as arteriolar and capillary thrombosis with abnormalities in the endothelium and vessel walls. The major etiological agent of HUS is enterohemorragic (E coli) strain belonging to serotype O157:H7. The lack of papers about HUS associated to gastroenteritis lead us to report this case for explain the symptoms that are uncommon. Furthermore, this report provides some strategies to suspect and make an early diagnosis, besides treatment approach to improving outcomes and prognosis for patients with this disorder.
- Heart failure affects liver morphology and function. What are the clinical implications? [Journal Article]
- BLBratisl Lek Listy 2018; 119(2):98-102
- Liver dysfunction in heart failure is common and usually clinically significant, especially in patients with advanced or severe acute heart failure. Lesions are caused by an impaired hepatic circulat...
Liver dysfunction in heart failure is common and usually clinically significant, especially in patients with advanced or severe acute heart failure. Lesions are caused by an impaired hepatic circulation due to congestion and hypoperfusion. Congestive lesions are more common and typically manifested by painful hepatomegaly and increased direct bilirubin and alkaline phosphatase. The inferior vena cava and hepatic veins are usually dilated. Congestive lesions are characterized by dilatation of the central vein with fibrotic changes in the surrounding areas on histological examination. Isolated ischaemic lesions are rare and occur due to severe and prolonged ineffective perfusion, often accompanied by hypoxemia. Ineffective perfusion is reflected by an increase in total bilirubin and significantly increased transaminase levels. The prognosis of ischaemic lesions without an adequate treatment of the cause of hypoperfusion is poor. Increased levels of bilirubin and liver function tests, as well as signs of impaired liver proteosynthetic function, are associated with a poor prognosis. Knowledge of the phenotypes of hepatic lesions in heart failure is important to select the appropriate treatment for an acute decompensation. Changes in biochemical markers, hepatic perfusion or stiffness of the liver can be used to evaluate the effectiveness of diuretic treatment and achieve euvolemic status in the patients with heart failure (Tab. 1, Fig. 3, Ref. 28).
- Live donor liver transplantation for acute liver failure: A single center experience. [Journal Article]
- IJIndian J Gastroenterol 2018 Feb 17
- CONCLUSIONS: In our experience, LDLT is an alternative procedure to DDLT in patients with ALF and is associated with good outcomes even in patients with high grades of encephalopathy.
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- Hybrid Retrograde Celiac Artery Stenting for Acute Mesenteric Ischemia after Gastric Surgery. [Journal Article]
- AVAnn Vasc Surg 2018 Feb 15
- CONCLUSIONS: Ischemic hepatitis is a rare but serious complication of CA/SMA occlusive disease. Its occurrence is at increased risk after surgeries where collateral flow is compromised. The endovascular treatment is currently the preferred approach to treat visceral arteries occlusive disease, however, antegrade CA cannulation can be tricky and, in an open abdomen scenario, retrograde approach from the splenic artery can be an additional resource. This case demonstrates the flexibility of endovascular techniques and that they can provide useful solutions even during open surgery.