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18,311,480 results
  • New 6,19-oxidoandrostan derivatives obtained by biotransformation in environmental filamentous fungi cultures. [Journal Article]
    Microb Cell Fact 2020; 19(1):37Kozłowska E, Matera A, … Janeczko T
  • CONCLUSIONS: As a result of the biotransformations, seven steroid derivatives, not previously described in the literature, were obtained: 3β-hydroxy-5α-chloro-6,19-oxidoandrostan-17-one, 3β,17α-dihydroxy-5α-chloro-6,19-oxidoandrostane, 3β-hydroxy-5α-chloro-17α-oxa-D-homo-6,19-oxidoandrostan-17-one, 3β,11α-dihydroxy-5α-chloro-17α-oxa-D-homo-6,19-oxidoandrostan-17-one and the three above-mentioned 11α-hydroxy derivatives. This study will allow a better understanding and characterisation of the catalytic abilities of individual microorganisms, which is crucial for more accurate planning of experiments and achieving more predictable results.
  • A computational platform to identify origins of replication sites in eukaryotes. [Journal Article]
    Brief Bioinform 2020Dao FY, Lv H, … Lin H
  • The locations of the initiation of genomic DNA replication are defined as origins of replication sites (ORIs), which regulate the onset of DNA replication and play significant roles in the DNA replication process. The study of ORIs is essential for understanding the cell-division cycle and gene expression regulation. Accurate identification of ORIs will provide important clues for DNA replication…
  • [Survey on Toxoplasma gondii infections among three types of populations in Wuxi City]. [Journal Article]
    Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2019; 31(6):662-664Xiao XZ, Zhou ZM, … Shen GQ
  • CONCLUSIONS: The patients with rheumatoid arthritis, malignant tumors and schizophrenia present with higher seroprevalence of the anti-T. gondii IgG antibody than healthy controls in Wuxi regions. Screening of T. gondii infections among the patients with rheumatoid arthritis, malignant tumors and schizophrenia should be intensified to prevent the damages caused by T. gondii infections.
  • [Epidemic situation of malaria in Jiangsu Province in 2018]. [Journal Article]
    Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2019; 31(6):649-651Wang WM, Cao YY, … Cao J
  • CONCLUSIONS: There are no local malaria cases in Jiangsu Province; however, the number of overseas imported malaria cases remains high in China. In the future, improving the post-elimination malaria surveillance system, enhancing the awareness of malaria prevention and control knowledge among high-risk populations, increasing the diagnostic capability of malaria in medical institutions, and improving the management of imported malaria cases should be performed to consolidate the achievements of malaria elimination.
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