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(Human Genome Project)
9,893 results
  • [Analysis of single-nucleotide polymorphism of Sonic hedgehog signaling pathway in non-syndromic cleft lip and/or palate in the Chinese population]. [Journal Article]
  • BDBeijing Da Xue Xue Bao Yi Xue Ban 2019 Jun 18; 51(3):556-563
  • Zhang JN, Song FQ, … Chen F
  • CONCLUSIONS: In China, NSCL/P is the most common congenital disease in orofacial region. However, as it is a multigenic disease and could be affected by multiple factors, such as the external environment, the etiology of NSCL/P has not been clearly defined. This study indicates that Shh signaling pathway is involved in the occurrence of NSCL/P, and some special SNP of key genes in this pathway are related to cleft lip and/or palate, which provides a new direction for the etiology research of NSCL/P and may provide help for the early screening and risk prediction of NSCL/P.
  • Presence of recombination hotspots throughout SLC6A3. [Journal Article]
  • PlosPLoS One 2019; 14(6):e0218129
  • Zhao J, Zhou Y, … Lin Z
  • The human dopamine transporter gene SLC6A3 is involved in substance use disorders (SUDs) among many other common neuropsychiatric illnesses but allelic association results including those with its cl…
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