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4,403 results
  • Behandling av akne. [Journal Article]
    Tidsskr Nor Laegeforen 2019; 139(12)Stangeland KZ, Huldt-Nystrøm T, … Danielsen K
  • Acne should not be perceived as a self-limiting affliction of adolescence. Due to the growing problem of antimicrobial-resistant bacteria, restrictive use of peroral and topical antibiotics is recommended. There are a number of effective agents for topical treatment of mild to moderate acne. In cases of severe, therapy-resistant acne, treatment with peroral isotretinoin is recommended.
  • Isotretinoin-induced sacroiliitis in patients with hidradenitis suppurativa: a case-based review. [Review]
    Rheumatol Int 2019Coskun BN, Yagiz B, … Dalkilic E
  • Hidradenitis suppurativa (HS) is a chronic, suppurative skin disease characterized by painful nodules, particularly in the axillae and groin. Isotretinoin can be used in the treatment of HS; however, it may paradoxically lead to skin lesions or worsen the existing lesions. Isotretinoin, which is commonly used in the treatment of severe acne, is associated with several side effects, including rheu…
  • A plea to stop using the case-control design in retrospective database studies. [Journal Article]
    Stat Med 2019; 38(22):4199-4208Schuemie MJ, Ryan PB, … Hripcsak G
  • The case-control design is widely used in retrospective database studies, often leading to spectacular findings. However, results of these studies often cannot be replicated, and the advantage of this design over others is questionable. To demonstrate the shortcomings of applications of this design, we replicate two published case-control studies. The first investigates isotretinoin and ulcerativ…
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