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Unbound Medicine.
(ISOtretinoin)
4,573 results
  • Isotretinoin-induced psychotic episode in a 17-year-old adolescent male. [Case Reports]
    SAGE Open Med Case Rep. 2020; 8:2050313X20931342.Elhusein B, Elkhaled W, … Al Abdulla M
  • Isotretinoin, a synthetic vitamin A derivative, is primarily used in the management of severe nodulocystic acne. Since its introduction, isotretinoin has been linked with various psychiatric side effects. In particular, depression and suicidality have been extensively reported as side effects. This case report features a young male who developed a first psychotic episode within 3 months of starti…
  • FASCE, the benefit of spironolactone for treating acne in women: study protocol for a randomized double-blind trial. [Journal Article]
    Trials. 2020 Jun 25; 21(1):571.Poinas A, Lemoigne M, … Dréno B
  • CONCLUSIONS: The treatment frequently used in female acne is systemic antibiotics with many courses, as it is a chronic inflammatory disease. In the context of the recent World Health Organisation (WHO) revelation about the serious, worldwide threat to public health of antibiotic resistance, this trial could give the physician another alternative in the treatment of adult female acne instead of using isotretinoin, which is more complex to manage.
  • The Effect of Isotretinoin on Vitiligo and Autoimmune Comorbidity. [Journal Article]
    J Drugs Dermatol. 2020 Jun 01; 19(6):637-638.O'Connor M, Silverberg JI, Silverberg NB
  • Several case reports have noted development of vitiligo as a potential side-effect of isotretinoin. In an IRB approved on-line survey of vitiligo patients we queried 1,301 vitiligo patients, 1115 with generalized vitiligo responding as to whether they had taken isotretinoin to address whether this issue was a common phenomenon amongst vitiligo patients. 3.6% of respondents had taken isotretinoin,…
  • Laser safety in isotretinoin use: online survey of public perception. [Journal Article]
    J Dermatolog Treat. 2020 Jun 14 [Online ahead of print]AlKhowailed M, AlWayili S, … Al-Hargan A
  • CONCLUSIONS: Even with the knowledge of recent safety data of laser during isotretinoin therapy, a significant proportion of patients are still concerned about potential complications. Increasing awareness regarding the safety of laser skin therapy during isotretinoin treatment might be needed.
  • The evaluation of the use of isotretinoin on vestibular system by using vHIT. [Journal Article]
    Am J Otolaryngol. 2020 Jun 02; 41(5):102579.Kocak E, Bozdemir K, … Dikicier BS
  • CONCLUSIONS: Although the studies demonstrating the effect of ISO on cochlea and symptoms occurring during treatment such as nausea, vomiting and vertigo suggest that it may exert effects on peripheral vestibular system, the present study indicates that it has no short terms effects on structures in peripheral vestibular system and vestibuloocular reflex pathways.
  • Erosive pustular dermatosis of the scalp: causes and treatments. [Review]
    Int J Dermatol. 2020 Jun 09 [Online ahead of print]Karanfilian KM, Wassef C
  • Erosive pustular dermatosis of the scalp is a rare condition which primarily affects older women after local trauma and has historically been treated with topical steroids. As it is a rare entity and resembles other dermatologic conditions, it may easily be misdiagnosed. Identifying the causes and evaluating the efficacy of treatments of erosive pustular dermatosis of the scalp (EPDS) is of great…
  • Linear porokeratosis presenting in adulthood: A diagnostic challenge: A case report. [Case Reports]
    SAGE Open Med Case Rep. 2020; 8:2050313X20919613.Nazarian RS, Hosseinipour M, … Cohen SR
  • Linear porokeratosis is a rare variant of porokeratosis that most often presents in newborns and children; development of this porokeratosis variant in adulthood is far less common. We report the case of a 25-year-old female who presented with a progressive eruption on the proximal upper extremity of 6-year duration, which was ultimately diagnosed as adult-onset linear porokeratosis and safely tr…
  • The Potential Uses of Omega-3 Fatty Acids in Dermatology: A Review. [Journal Article]
    J Cutan Med Surg. 2020 May 28 [Online ahead of print]Thomsen BJ, Chow EY, Sapijaszko MJ
  • CONCLUSIONS: This review yielded many well-studied benefits of O3FA uses in dermatology. Given its high safety profile, low cost, and ease of supplementation, O3FA is a reasonable supplement that may benefit patients wishing to improve inflammatory skin conditions through diet. Areas of particular clinical interest where supplementation may be valuable include O3FAs for systemic UV photoprotection, as well as adjuvant treatment for acne to reduce both inflammatory lesion count and the severity of mucocutaneous side effects associated with isotretinoin use.
  • Knowledge levels and concerns about oral isotretinoin treatment in the parents of adolescent acne patients. [Journal Article]
    Dermatol Ther. 2020 May 27 [Online ahead of print]Kara Polat A, Akin Belli A, … Gurel MS
  • Oral isotretinoin is frequently used in the treatment of young acne patients. However, knowledge levels and attitudes about this treatment have not been studied in the parents previously. We aimed to investigate the knowledge levels and concerns about oral isotretinoin in the parents of adolescent acne patients. We conducted a cross-sectional study on 136 parents of adolescent patients with moder…
  • Efficacy of acne vulgaris treatment protocols according to its clinical forms. [Journal Article]
    Dermatol Ther. 2020 May 17 [Online ahead of print]Jorgaqi E, Savo I, … Jafferany M
  • To compare results of different treatment regimens based on stratification of acne to prescribe the right treatment protocol according to clinical form and grade of acne. A transversal, cohort study conducted in 230 patients with acne vulgaris. Patients were divided into three groups according to acne severity and the results of each protocol determined in 0, 4, 6, 8, 12, 18 and 24 weeks. Statist…
  • Frontal Fibrosing Alopecia: A Retrospective Study of 75 Patients. [Journal Article]
    Actas Dermosifiliogr. 2020 May 14 [Online ahead of print]Maldonado Cid P, Leis Dosil VM, … Díaz Díaz RM
  • CONCLUSIONS: Most of the patients in this series of FFA were postmenopausal women. The prevalence of oral and genital lichen planus was higher than that observed in the general population. Patients with a linear pattern had less severe disease. Facial papules were more common in younger patients and both facial papules and rosacea were associated with a greater need for oral treatment.
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