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(Japan AND ("Novel Coronavirus" OR COVID-19 OR SARS-CoV-2 OR 2019-nCoV))
3,623 results
  • Population Pharmacokinetics of Favipiravir in Patients with COVID-19. [Journal Article]
    CPT Pharmacometrics Syst Pharmacol. 2021 Jul 22 [Online ahead of print]Irie K, Nakagawa A, … Hashida T
  • The antiretroviral drug favipiravir inhibits RNA-dependent RNA polymerase. It has been developed for the treatment of novel coronavirus (SARS-CoV-2) infection disease (COVID-19). However, its pharmacokinetics in patients with COVID-19 is poorly understood. In this study, we measured favipiravir serum concentration by liquid chromatography-tandem mass spectrometry and conducted population pharmaco…
  • B-cell depletion therapy for multiple sclerosis. [Journal Article]
    Immunol Med. 2021 Jul 21 [Online ahead of print]Miyazaki Y, Niino M
  • Since the initial observation of increased immunoglobulin concentrations in the cerebrospinal fluid of multiple sclerosis (MS) patients in the 1940s, B cells have been considered to participate in the pathology of MS through the production of autoantibodies reactive against central nervous system antigens. However, it is now recognized that B cells contribute to MS relapses via antibody-independe…
  • COVID-19: Thrombosis, thromboinflammation, and anticoagulation considerations. [Review]
    Int J Lab Hematol. 2021 Jul; 43 Suppl 1:29-35.Levy JH, Iba T, … Connors JM
  • Vascular endothelial injury is a hallmark of acute infection at both the microvascular and macrovascular levels. The hallmark of SARS-CoV-2 infection is the current COVID-19 clinical sequelae of the pathophysiologic responses of hypercoagulability and thromboinflammation associated with acute infection. The acute lung injury that initially occurs in COVID-19 results from vascular and endothelial …
  • COVID-19 and nursing research across five countries/regions: Commonalities and recommendations. [Journal Article]
    Res Nurs Health. 2021 Jul 21 [Online ahead of print]Im EO, Sakashita R, … McCauley L
  • With the recent impact by the COVID-19 pandemic, nursing research has gone through unexpected changes across the globe. The purpose of this special report is to present the commonalities in the impact of the COVID-19 pandemic on nursing research across four countries, including the United States, South Korea, Japan, and Taiwan, and one region, that is, Hong Kong, and to make recommendations for f…
  • Early approval of COVID-19 vaccines: Pros and cons. [Journal Article]
    Hum Vaccin Immunother. 2021 Jul 20 [Online ahead of print]Rahman MA, Islam MS
  • The development of safe and effective vaccines has been an overriding priority for controlling the 2019-coronavirus disease (COVID-19) pandemic. From the onset, COVID-19 has caused high mortality and economic losses and yet has also offered an opportunity to advance novel therapeutics such as DNA and mRNA vaccines. Although it is hoped that the swift acceptance of such vaccines will prevent loss …
  • Subacute SARS-CoV-2 replication can be controlled in the absence of CD8+ T cells in cynomolgus macaques. [Journal Article]
    PLoS Pathog. 2021 Jul 19; 17(7):e1009668.Nomura T, Yamamoto H, … Matano T
  • SARS-CoV-2 infection presents clinical manifestations ranging from asymptomatic to fatal respiratory failure. Despite the induction of functional SARS-CoV-2-specific CD8+ T-cell responses in convalescent individuals, the role of virus-specific CD8+ T-cell responses in the control of SARS-CoV-2 replication remains unknown. In the present study, we show that subacute SARS-CoV-2 replication can be c…
  • Prevalence of COVID-19 and the Continued Citizen-Based Control in Japan. [Journal Article]
    Adv Exp Med Biol. 2021; 1327:25-33.Yanase S, Sugimori H
  • Since an outbreak of COVID-19 was detected among the crew and passengers of the Diamond Princess cruise ship in early 2020, the total number of cases of SARS-CoV-2 has surpassed 440,000 in Japan. However, that number remains small compared with other countries, such as the United States, a few European countries, and China. Despite the Japanese government not imposing a lockdown or implementing l…
  • Who is more likely to ignore experts' advice related to COVID-19? [Journal Article]
    Prev Med Rep. 2021 Sep; 23:101470.O'Shea BA, Ueda M
  • Failing to adhere to COVID-19 experts' advice could have devastating consequences for individuals and communities. Here we determine which demographic factors can impact trust in COVID-19 experts. Participants consisted of more than 1875 online volunteers, primarily from the U.S. Survey data were collected before and after the first peak of the COVID-19 outbreak in the U.S. (28th of March-15th of…
  • Coronavirus Disease 2019 and the Thyroid - Progress and Perspectives. [Review]
    Front Endocrinol (Lausanne). 2021; 12:708333.Inaba H, Aizawa T
  • SARS-CoV-2 infection (COVID-19) is currently a tremendous global health problem. COVID-19 causes considerable damage to a wide range of vital organs most prominently the respiratory system. Recently, clinical evidence for thyroidal insults during and after COVID-19 has been accumulated. As of today, almost all non-neoplastic thyroid diseases, i.e., Graves' disease, Hashimoto's thyroiditis, subacu…
  • Who Is Next? A Study on Victims of Financial Fraud in Japan. [Journal Article]
    Front Psychol. 2021; 12:649565.Kadoya Y, Khan MSR, … Watanabe S
  • Japan has seen an increase in the incidents of financial frauds over the last couple of decades. Although authorities are aware of the problem, an effective solution eludes them as fraudsters use innovative swindling methods and continually change the target group. Using a nationwide survey conducted by Hiroshima University, Japan, in 2020, this study investigated the socioeconomic and psychologi…
  • Diagnosis Of Covid-19 In Symptomatic Patients: An Updated Review. [Review]
    Vacunas. 2021 Jul 13 [Online ahead of print]Zahan MN, Habibi H, … Parvej MS
  • A group of pneumonia patients was detected in Hubei Province, in China in December 2019. The etiology of the disease was unknown. Later, the researchers diagnosed the novel Coronavirus as the causal agent of this respiratory disease. On February 12th 2020, the World Health Organization (WHO) officially named this disease Coronavirus disease 2019 (COVID-19). Consequently, the disease spread global…
  • Weather indicators and improving air quality in association with COVID-19 pandemic in India. [Journal Article]
    Soft comput. 2021 Jul 13 [Online ahead of print]Chakrabortty R, Pal SC, … Das B
  • The COVID-19 pandemic enforced nationwide lockdown, which has restricted human activities from March 24 to May 3, 2020, resulted in an improved air quality across India. The present research investigates the connection between COVID-19 pandemic-imposed lockdown and its relation to the present air quality in India; besides, relationship between climate variables and daily new affected cases of Cor…
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