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636,980 results
  • StatPearls [BOOK]
  • BOOKStatPearls Publishing: Treasure Island (FL)
  • Ojha Niranjan N B P Koirala Institute of Health Sciences Dhamoon Amit S. AS SUNY Upstate Medical University
  • Endocarditis is the inflammation of the endocardium, the innermost lining of the heart. Endocarditis may be due to infective or non-infective etiologies. Fungal endocarditis is an infrequent but debi...
  • StatPearls [BOOK]
  • BOOKStatPearls Publishing: Treasure Island (FL)
  • Santana Javier A. JA Universidad Ibercoamericana (UNIBE) Sherman Andrew l. Al Un of Miami Miller School of Med
  • “Jumper's knee,” also called patellar tendinopathy, is a painful condition of the knee caused by small tears in the patellar tendon that mainly occurs in sports requiring strenuous jumping. The tears...
  • StatPearls [BOOK]
  • BOOKStatPearls Publishing: Treasure Island (FL)
  • Mohseni Michael M Mayo Clinic Graham Charles C Mayo Clinic Florida
  • Bursitis is the general term used to describe inflammation of any bursae. The bursae are the cavitary structures lined with synovial tissue that cushion and assist during the motion of joints and mus...
  • StatPearls [BOOK]
  • BOOKStatPearls Publishing: Treasure Island (FL)
  • Schumann Jessica A. JA Jefferson Northeast Parente John J. JJ St. John Medical Center
  • Costochondritis is a chest wall pain caused by inflammation of the costal cartilages or the area where they meet the sternum, known as sternal articulations. It is a benign cause of chest pain. Patie...
  • StatPearls [BOOK]
  • BOOKStatPearls Publishing: Treasure Island (FL)
  • Yam Julie J McLaren Greater Lansing Bhimji Steve S. SS Un of Toronto
  • An esophageal diverticulum is a relatively rare disease of the esophagus.[1] It is an outpouching of the esophageal mucosa and is usually asymptomatic. Patients typically present when they have sympt...
  • Biochemical Markers, Genotype, and Inflammation in Pediatric Inflammatory Bowel Disease: A Danish Population-Based Study. [Journal Article]
  • DDDig Dis 2018 Nov 13; :1-7
  • Ziade F, Rungoe C, … Jakobsen C
  • CONCLUSIONS: Patients were included from a population-based pediatric IBD cohort from Eastern Denmark. Data on biochemical markers and medical as well as surgical treatment were registered at diagnosis, 30 days, 6 and 12 months after diagnosis. Fifty-two single nucleotide polymorphisms (SNPs) known to be associated with IBD were selected for genotyping based on previous genetic studies. Key messages: A total of 190 IBD patients (97 ulcerative colitis [UC], 87 Crohn's disease [CD], and 6 IBD unclassified) were included. UC patients with extensive disease had higher C-reactive protein, erythrocyte sedimentation rate, and platelet count at diagnosis compared to UC patients with less extensive disease. No similar differences between disease extent groups were found in CD. Low albumin at diagnosis was associated with an increased risk of surgery in both UC (OR 1.35; 95% CI: 1.05-1.75) and CD patients (OR 1.23; 95% CI: 1.01-1.48) and increased use of azathioprine and anti-tumor necrosis factor alpha use in the total IBD cohort (OR 1.15; 95% CI: 1.04-1.27 and OR 1.19 [1.08-1.34]). One SNP (rs4986791 in the TLR-4 locus) and 2 SNPs (rs6785049 in the Pregnane-x-receptor gene and rs10500264 in the SLCA10 gene) were associated with a change in albumin and hemoglobin over time respectively in our IBD cohort. Our study confirms albumin to be a marker of severe disease course. Furthermore, the patient's genotype possibly affects the inflammatory response. Future studies in larger pediatric cohorts are needed to confirm our findings.
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