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36,227 results
  • Microbiological survey of sugar gliders (Petaurus breviceps) kept as pets in Italy. [Journal Article]
    Lett Appl Microbiol 2019Varriale L, Russo TP, … Dipineto L
  • The sugar glider (Petaurus breviceps) is a small, arboreal, nocturnal, gliding mammalian possum belonging to the marsupial infraclass. Exotic marsupials, including sugar gliders, are becoming popular companion pets and, consequently, the risk of potential infections that can be transmitted to humans should be investigated. Data on the role of the sugar glider as a possible carrier of pathogenic a…
  • Small Klebsiella pneumoniae Plasmids: Neglected Contributors to Antibiotic Resistance. [Journal Article]
    Front Microbiol 2019; 10:2182Ramirez MS, Iriarte A, … Tolmasky ME
  • Klebsiella pneumoniae is the causative agent of community- and, more commonly, hospital-acquired infections. Infections caused by this bacterium have recently become more dangerous due to the acquisition of multiresistance to antibiotics and the rise of hypervirulent variants. Plasmids usually carry genes coding for resistance to antibiotics or virulence factors, and the recent sequence of comple…
  • Structural insight into the carboxylesterase BioH from Klebsiella pneumoniae. [Journal Article]
    Biochem Biophys Res Commun 2019Wang L, Chen Y, … Xu Y
  • The BioH carboxylesterase which is a typical α/β-hydrolase enzyme involved in biotin synthetic pathway in most bacteria. BioH acts as a gatekeeper and blocks the further elongation of its substrate. In the pathogen Klebsiella pneumoniae, BioH plays a critical role in the biosynthesis of biotin. To better understand the molecular function of BioH, we determined the crystal structure of BioH from K…
  • Alliance of Efflux Pumps with β-Lactamases in Multidrug-Resistant Klebsiella pneumoniae Isolates. [Journal Article]
    Microb Drug Resist 2019; 25(8):1155-1163Maurya N, Jangra M, … Nandanwar H
  • Nosocomial infections caused by Klebsiella pneumoniae are primarily characterized by a high prevalence of extended-spectrum β-lactamases (ESBL's) and a soaring pace of carbapenemase dissemination. Availability of limited antimicrobial agents as a therapeutic option for multidrug-resistant bacteria raises an alarming concern. This study aimed at the molecular characterization of multidrug-resistan…
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