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2,476 results
  • Systemic minoxidil for hair disorders in pediatric patients: a safety and tolerability review. [Journal Article]
    Int J Dermatol. 2022 Aug 14 [Online ahead of print]John JM, Sinclair RD
  • Topical minoxidil has been used for many years to treat adult alopecia, and there is growing evidence supporting the off-label use of low-dose oral minoxidil (LDOM). However, there is little data on its use in pediatrics, and there are no recommended treatment guidelines. Adverse events are of particular concern in this population. We retrospectively reviewed the medical records of 63 patients ag…
  • Conditioned media-integrated microneedles for hair regeneration through perifollicular angiogenesis. [Journal Article]
    J Control Release. 2022 Aug 09 [Online ahead of print]Yuan A, Gu Y, … Gao J
  • Androgenetic alopecia (AGA), the most prevalent type of hair loss in clinic, is induced partly by insufficient perifollicular vascularization. Here we designed a dissolvable microneedles (MNs) patch that was loaded with conditioned media (CM) derived from hypoxia-pretreated mesenchymal stem cells, which contained elevated HIF-1α. The CM-integrated MNs patch (designated as CM-MNs) can puncture the…
  • Noninvasive Hair Rejuvenation. [Review]
    Facial Plast Surg Clin North Am. 2022 Aug; 30(3):419-431.Sand J, Walen S
  • Both nonsurgical and surgical modalities for the treatment of hair loss are being used by providers at an increasing rate worldwide. Men and woman are affected by hair loss, but the pathophysiology of the hair loss is thought to be different between sexes; therefore, gender must play a role in treatment decisions. Currently, there are 3 Food and Drug Administration-approved nonsurgical androgenet…
  • Comparison of oral minoxidil, finasteride, and dutasteride for treating androgenetic alopecia. [Review]
    J Dermatolog Treat. 2022 Aug 15 [Online ahead of print]Gupta AK, Talukder M, Williams G
  • Androgenetic alopecia (AGA) is the most common cause of hair loss, often challenging to treat. While oral finasteride (1 mg/d) is an FDA-approved treatment for male AGA, oral minoxidil and oral dutasteride are not approved yet. However, clinicians have been increasingly using these two drugs off-label for hair loss. Recently, Japan and South Korea have approved oral dutasteride (0.5 mg/d) for mal…
  • Does topical minodixil in concentrations higher than 5% provide additional clinical benefit? [Review]
    Clin Exp Dermatol. 2022 Jul 26 [Online ahead of print]Goldust M, Singh S, … Sinclair R
  • Minoxidil solution is used for the treatment of androgenic alopecia. While the 5% minoxidil solution has superior efficacy to the 2% solution, it is unknown whether concentrations of minoxidil higher than 5% provide additional clinical benefit. We performed a review of the literature to examine the evidence on the efficacy and safety of higher concentrations of minoxidil in AGA. "PubMed" search w…
  • COVID-19-induced Scalp Alopecia Treated Effectively with Stem Cell Serum. [Case Reports]
    Plast Reconstr Surg Glob Open. 2022 Jun; 10(6):e4423.Ong SWQ, Ong KHX, Lee SJ
  • Up to 36.7% of symptomatic COVID-19 patients will have telogen effluvium (TE), which refers to diffuse scalp alopecia. With the continuing global pandemic, a review of literature reports unpredictable and incomplete recovery with conventional treatment like minoxidil. The pathogenesis of COVID-19-induced TE may be more severe than that of conventional TE as the hair follicles are proposed to be d…
  • ATP-sensitive potassium channels: A double-edged sword in neurodegenerative diseases. [Review]
    Ageing Res Rev. 2022 Sep; 80:101676.Lv J, Xiao X, … Jiang H
  • ATP-sensitive potassium channels (KATP channels), a group of vital channels that link the electrical activity of the cell membrane with cell metabolism, were discovered on the ventricular myocytes of guinea pigs by Noma using the patch-clamp technique in 1983. Subsequently, KATP channels have been found to be expressed in pancreatic β cells, cardiomyocytes, skeletal muscle cells, and nerve cells …
  • Pleural Effusion Indued By Systemic Consumption Of Topical Minoxidil: A Rare Case Report. [Case Reports]
    Curr Drug Saf. 2022 Jun 08 [Online ahead of print]Ty SH, Kumar KSP, … Thangaraju P
  • CONCLUSIONS: Minoxidil is a commonly used drug by many people for the treatment of hair fall with or without doctor advice. We would like to stress that even though rare, physicians/pulmonologists should be aware of its rare side effects of topical minoxidil, and it should be kept in mind as a differential diagnosis for pleural effusion.
  • Reversible Hair Loss in Lichen Planopilaris: Regrowth With Low-Dose Naltrexone and Platelet-Rich Plasma. [Case Reports]
    J Drugs Dermatol. 2022 Jun 01; 21(6):671-673.Klein E, Karim M, … Shapiro J
  • Lichen planopilaris (LPP) is a cicatricial alopecia that presents with patchy or diffuse hair loss at the vertex or parietal scalp. The literature has limited evidence on treatments for this challenging disease, with most reports involving small groups of patients with varied or suboptimal clinical responses. Amongst individuals who do respond to therapy and eventually achieve disease remission, …
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