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(M4Eo)
205 results
  • Myeloid Sarcoma With CBFB-MYH11 Fusion (inv(16) or t(16;16)) Prevails in the Abdomen. [Journal Article]
    Am J Clin Pathol 2019Dalland JC, Meyer R, … Reichard KK
  • CONCLUSIONS: Our current series, combined with a literature review, identifies a compelling series of 31 (94%) of 33 cases of myeloid sarcoma with CBFB-MYH11 fusion showing a marked predilection for abdominal sites. In addition, the lack of obvious associated eosinophils, presence of pDC nodules, and lack of concurrent BM involvement suggest that "myeloid sarcoma with CBFB-MYH11 fusion" may represent a unique phenomenon.
  • Acute myeloid leukaemia (FAB AML-M4Eo) with cryptic insertion of cbfb resulting in cbfb-Myh11 fusion. [Case Reports]
    Hematol Oncol 2017; 35(3):385-389Douet-Guilbert N, Chauveau A, … De Braekeleer M
  • Inv(16)(p13q22) and t(16;16)(p13;q22) are cytogenetic hallmarks of acute myelomonoblastic leukaemia, most of them associated with abnormal bone marrow eosinophils [acute myeloid leukaemia French-American-British classification M4 with eosinophilia (FAB AML-M4Eo)] and a relatively favourable clinical course. They generate a 5'CBFB-3'MYH11 fusion gene. However, in a few cases, although RT-PCR ident…
  • [Clinical analysis of acute myeloid leukemia with CBFB-MYH11-positive]. [Journal Article]
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 2013; 21(2):305-10Cao TT, Zhou MH, … Jing Y
  • The study was aimed to investigate the clinical characteristics of acute myeloid leukemia (AML) with CBFB-MYH11 gene. The clinical data of 12 cases were analyzed retrospectively, including age, clinical characteristics, immunophenotype, treatment protocols and efficacy as well as the prognosis. The results indicated that 12 patients with CBFB-MYH11 were detected in 293 AML patients. The median ag…
  • Acute myeloid leukemia with cryptic CBFB-MYH11 type D. [Case Reports]
    Int J Clin Exp Pathol 2013; 6(1):110-2Kobayashi T, Ichikawa M, … Kurokawa M
  • A 77 year-old female was found with FAB M4Eo acute myeloid leukemia. Although CBFB-MYH11 mRNA was detected in RT-PCR, the conventional cytogenetic analysis failed to reveal inv(16). Fluorescence in situ hybridization (FISH) and the sequence analysis revealed a fusion between the exon 5 of CBFB and the exon 8 of MYH11, resulting in a minor variant fusion product previously reported as type D. In o…
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