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1,464 results
  • Clinical and Radiological Outcomes After Revascularization of Hemorrhagic Moyamoya Disease. [Journal Article]
    Front Neurol. 2020; 11:382.Kang K, Lu J, … Zhao X
  • Objective: To evaluate clinical and radiological outcomes after revascularization of hemorrhagic moyamoya disease (MMD). Materials and Methods: We retrospectively collected patients with hemorrhagic MMD who received revascularization from January 2011 to June 2018 at a high-volume stroke center. Rebleeding, ischemic stroke, modified Rankin Scale (mRS) and death after revascularization were used…
  • Characteristics of myopic traction maculopathy in myopic Singaporean adults. [Journal Article]
    Br J Ophthalmol. 2020 May 23 [Online ahead of print]Matsumura S, Sabanayagam C, … Saw SM
  • CONCLUSIONS: Our population-based study revealed that MTM was present in 0.9% of myopic eyes and 7.3% of highly myopic eyes. While greater myopic SE, longer AL, MMD and epiretinal traction are risk factors of MTM, age was not related to MTM. MTM has a negative effect on BCVA.
  • Actinobacterial Coproheme Decarboxylases Use Histidine as a Distal Base to Promote Compound I Formation. [Journal Article]
    ACS Catal. 2020 May 15; 10(10):5405-5418.Michlits H, Lier B, … Hofbauer S
  • Coproheme decarboxylases (ChdCs) catalyze the final step in heme b biosynthesis of monoderm and some diderm bacteria. In this reaction, coproheme is converted to heme b via monovinyl monopropionate deuteroheme (MMD) in two consecutive decarboxylation steps. In Firmicutes decarboxylation of propionates 2 and 4 of coproheme depend on hydrogen peroxide and the presence of a catalytic tyrosine. Here …
  • PHACTR1 is associated with disease progression in Chinese Moyamoya disease. [Journal Article]
    PeerJ. 2020; 8:e8841.Yang Y, Wang J, … Zhu Y
  • Moyamoya disease (MMD) is a progressive stenosis at the terminal portion of internal carotid artery and frequently occurs in East Asian countries. The etiology of MMD is still largely unknown. We performed a case-control design with whole-exome sequencing analysis on 31 sporadic MMD patients and 10 normal controls with matched age and gender. Patients clinically diagnosed with MMD was determined …
  • Association of Brain-Gut Peptides with Inflammatory Cytokines in Moyamoya Disease. [Journal Article]
    Mediators Inflamm. 2020; 2020:5847478.Han W, Jin F, … Jiang P
  • Systemic inflammation has been shown to play a pivotal role in the pathogenesis of moyamoya disease (MMD). Brain-gut peptides exhibit regulatory effects in the secretion of proinflammatory cytokines. To investigate the association between brain-gut peptides and inflammation in the occurrence of MMD, 41 patients with MMD, as well as 74 age- and sex-matched healthy individuals were enrolled. The le…
  • Association of Genetic Variants With Moyamoya Disease in 13 000 Individuals: A Meta-Analysis. [Journal Article]
    Stroke. 2020 Jun; 51(6):1647-1655.Wang X, Wang Y, … Liu W
  • Background and Purpose- A growing body of evidence indicates genetic components play critical roles in moyamoya disease (MMD). Firm conclusions from studies of this disease have been stymied by small sample sizes and a lack of replicative results. This meta-analysis was conducted to determine whether these genetic polymorphisms are associated with MMD. Methods- PubMed, Google Scholar, Embase, Wan…
  • Development and validation of a risk scoring model for postoperative adult moyamoya disease. [Journal Article]
    J Neurosurg. 2020 May 08 [Online ahead of print]Kim M, Park W, … Lee S
  • CONCLUSIONS: The authors' scoring system is readily adoptable to predict the postoperative outcome for MMD. Their data revealed the importance of smoking and hyperlipidemia, which were the only modifiable factors included in the scoring system. The authors validated their scoring system both internally and externally and maintained good performance, highlighting the system's generalizability and reliability.
  • [Discharge management in German hospitals for cognitively impaired, older people-a scoping review]. [Review]
    Z Gerontol Geriatr. 2020 May 07 [Online ahead of print]Schumacher-Schönert F, Wucherer D, … Thyrian JR
  • CONCLUSIONS: The article illustrates significant gaps in the hospital care for older MmkB, in particular at the interface of discharge management and demonstrates the need for new care models. To what extent these new care models can be structurally, procedurally and systemically embedded in the standard care and financed, is an open and unexplored question.
  • Metabolomic Profiling Revealed Potential Biomarkers in Patients With Moyamoya Disease. [Journal Article]
    Front Neurosci. 2020; 14:308.Geng C, Cui C, … Jiang P
  • Metabolomics is increasingly used to observe metabolic patterns and disease-specific metabolic biomarkers. However, serum metabolite analysis of moyamoya disease (MMD) is rarely reported. We investigated serum metabolites in MMD and compared them with those of healthy controls (HCs) using a non-targeted gas chromatography-mass spectrometry (GC-MS) approach to identify metabolic biomarkers associa…
  • The Complications of Myopia: A Review and Meta-Analysis. [Journal Article]
    Invest Ophthalmol Vis Sci. 2020 Apr 09; 61(4):49.Haarman AEG, Enthoven CA, … Klaver CCW
  • CONCLUSIONS: Although high myopia carries the highest risk of complications and visual impairment, low and moderate myopia also have considerable risks. These estimates should alert policy makers and health care professionals to make myopia a priority for prevention and treatment.
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