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  • Perspectives on preconception health among migrant women in Australia: A qualitative study. [Journal Article]
    Women Birth 2019Lang AY, Bartlett R, … Boyle JA
  • CONCLUSIONS: Information for women addressing preconception health and pregnancy planning is limited. Our study demonstrates additional cultural and social nuances that need to be understood when working with migrant women. Discomfort raising reproductive and preconception health discussions with healthcare providers was a reported concern. Integration of culturally-sensitive preconception care within routine client assessments warrants exploration. Emphasis of the importance of preconception care for all women is needed.
  • Severity as a Priority Setting Criterion: Setting a Challenging Research Agenda. [Journal Article]
    Health Care Anal 2019Barra M, Broqvist M, … Solberg CT
  • Priority setting in health care is ubiquitous and health authorities are increasingly recognising the need for priority setting guidelines to ensure efficient, fair, and equitable resource allocation. While cost-effectiveness concerns seem to dominate many policies, the tension between utilitarian and deontological concerns is salient to many, and various severity criteria appear to fill this gap…
  • A Review of the Therapeutic Potential of Recently Developed G Protein-Biased Kappa Agonists. [Review]
    Front Pharmacol 2019; 10:407Mores KL, Cummins BR, … van Rijn RM
  • Between 2000 and 2005 several studies revealed that morphine is more potent and exhibits fewer side effects in beta-arrestin 2 knockout mice. These findings spurred efforts to develop opioids that signal primarily via G protein activation and do not, or only very weakly, recruit beta-arrestin. Development of such molecules targeting the mu opioid receptor initially outpaced those targeting the ka…
  • Diabetic retinopathy, a vascular and inflammatory disease: Therapeutic implications. [Review]
    Diabetes Metab 2019Semeraro F, Morescalchi F, … Costagliola C
  • Diabetic retinopathy (DR) is the most common microvascular complication of diabetes and the leading cause of visual impairment in the working-age population in the Western world. Diabetic macular oedema (DME) is one of the major complications of DR. Therapy with intravitreal injections of anti-vascular endothelial growth factor (anti-VEGF) drugs has become the gold standard treatment for DR and i…
  • IL-17-high asthma with features of a psoriasis immunophenotype. [Journal Article]
    J Allergy Clin Immunol 2019Östling J, van Geest M, … U-BIOPRED Study Group
  • CONCLUSIONS: The IL-17-high asthma phenotype, characterized by bronchial epithelial dysfunction and upregulated antimicrobial and inflammatory response, resembles the immunophenotype of psoriasis, including activation of the thromboxane B2 pathway, which should be considered a biomarker for this phenotype in further studies, including clinical trials targeting IL-17.
  • High frequency and molecular characterization of porcine hemotrophic mycoplasmas in Brazil. [Journal Article]
    Vet Microbiol 2019; 231:33-39Gatto IRH, Sonálio K, … de Oliveira LG
  • Mycoplasma suis and Mycoplasma parvum are the two hemotrophic mycoplasmas species described in pigs. M. suis is involved in infectious anemia, while M parvum infection is commonly subclinical. The objectives of this study were twofold: (i) to investigate the prevalence of porcine hemotrophic mycoplasmas in sows from the southern region of Brazil by quantitative real-time PCR (qPCR) and (ii) to ge…
  • Stratification of asthma phenotypes by airway proteomic signatures. [Journal Article]
    J Allergy Clin Immunol 2019; 144(1):70-82Schofield JPR, Burg D, … U-BIOPRED Study Group
  • CONCLUSIONS: This study provides further stratification of asthma currently classified based on quantification of granulocytic inflammation and provided additional insight into their underlying mechanisms, which could become targets for novel therapies.
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