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(Macronutrients in Health and Disease)
365 results
  • Diet as Regulator of Gut Microbiota and its Role in Health and Disease. [Review]
    Arch Med Res 2019; 50(5):259-268Sánchez-Tapia M, Tovar AR, Torres N
  • In recent years, the gut microbiota has been of great interest due to its role in maintaining health and its association with the development of different diseases such as obesity and diabetes. The objective of the present review is to show the main functions of the gut microbiota, the role in the degradation of complex carbohydrates particularly soluble fiber, resistant starches and bioactive co…
  • Tryptophan Dietary Impacts Gut Barrier and Metabolic Diseases. [Review]
    Front Immunol 2019; 10:2113Taleb S
  • The intestine has a major role in the digestion and absorption of nutrients, and gut barrier is the first defense line against harmful pathogens. Alteration of the intestinal barrier is associated with enhanced intestinal permeability and development of numerous pathological diseases including gastrointestinal and cardiometabolic diseases. Among the metabolites that play an important role within …
  • d-amino Acids in Health and Disease: A Focus on Cancer. [Review]
    Nutrients 2019; 11(9)Bastings JJAJ, van Eijk HM, … Rensen SS
  • d-amino acids, the enantiomeric counterparts of l-amino acids, were long considered to be non-functional or not even present in living organisms. Nowadays, d-amino acids are acknowledged to play important roles in numerous physiological processes in the human body. The most commonly studied link between d-amino acids and human physiology concerns the contribution of d-serine and d-aspartate to ne…
  • Beneficial Effects of Dietary Polyphenols on Gut Microbiota and Strategies to Improve Delivery Efficiency. [Review]
    Nutrients 2019; 11(9)Kumar Singh A, Cabral C, … Pandey AK
  • The human intestine contains an intricate ecological community of dwelling bacteria, referred as gut microbiota (GM), which plays a pivotal role in host homeostasis. Multiple factors could interfere with this delicate balance, including genetics, age, antibiotics, as well as environmental factors, particularly diet, thus causing a disruption of microbiota equilibrium (dysbiosis). Growing evidence…
  • Regulation of bile acid metabolism-related signaling pathways by gut microbiota in diseases. [Journal Article]
    J Zhejiang Univ Sci B 2019 Oct.; 20(10):781-792Jia ET, Liu ZY, … Ge QY
  • Over the past decade, there has been increasing attention on the interaction between microbiota and bile acid metabolism. Bile acids are not only involved in the metabolism of nutrients, but are also important in signal transduction for the regulation of host physiological activities. Microbial-regulated bile acid metabolism has been proven to affect many diseases, but there have not been many st…
  • Effects of Olive Oil and Its Minor Components on Cardiovascular Diseases, Inflammation, and Gut Microbiota. [Review]
    Nutrients 2019; 11(8)Marcelino G, Hiane PA, … Guimarães RCA
  • Olive oil is one of the main ingredients in the Mediterranean diet, being an important ally in disease prevention. Its nutritional composition is comprised of mainly monounsaturated fatty acids, with oleic being the major acid, plus minor components which act as effective antioxidants, such as hydroxytyrosol. Studies have shown that the consumption of olive oil, as well as its isolated components…
  • Phytochemicals in Prostate Cancer: From Bioactive Molecules to Upcoming Therapeutic Agents. [Review]
    Nutrients 2019; 11(7)Salehi B, Fokou PVT, … Sharifi-Rad J
  • Prostate cancer is a heterogeneous disease, the second deadliest malignancy in men and the most commonly diagnosed cancer among men. Traditional plants have been applied to handle various diseases and to develop new drugs. Medicinal plants are potential sources of natural bioactive compounds that include alkaloids, phenolic compounds, terpenes, and steroids. Many of these naturally-occurring bioa…
  • Selenium and Health: An Update on the Situation in the Middle East and North Africa. [Journal Article]
    Nutrients 2019; 11(7)Ibrahim SAZ, Kerkadi A, Agouni A
  • Selenium (Se) is an important trace element that should be present in the diet of all age groups to provide an adequate intake. Se is incorporated in 25 known selenoproteins, which mediate the biological effects of Se including, immune response regulation, maintenance of thyroid function, antioxidant defense, and anti-inflammatory actions. A balanced intake of Se is critical to achieve health ben…
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