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5,249 results
  • Lessons from mass vaccination response to meningococcal B outbreaks at US universities. [Journal Article]
    Postgrad Med. 2020 Jun 01 [Online ahead of print]Alderfer J, Isturiz RE, Srivastava A
  • College students in the United States are at an increased risk for meningococcal serogroup B disease or MenB, which causes the majority of invasive meningococcal disease in the country among adolescents and young adults (62%) and also across all age groups (36%) as of 2018. Approximately one-third of MenB cases among college students occur during campus outbreaks, which trigger substantial public…
  • Neisseria meningitidis: analysis of pili and LPS in emerging Brazilian strains. [Journal Article]
    Ther Adv Vaccines Immunother. 2020; 8:2515135520919195.Portilho AI, Trzewikoswki de Lima G, De Gaspari E
  • CONCLUSIONS: Due to the impact of meningococcal disease, it is important to maintain and improve vaccine studies. Epitopes characterization provides data about the virulence of circulating strains. The use of monoclonal antibodies and serological techniques are relevant and support vaccine development.
  • Adolescent Vaccines: Current Recommendations and Techniques to Improve Vaccination Rates. [Review]
    Prim Care. 2020 Jun; 47(2):217-229.Adelman M, Barrickman AL, Garofoli GK
  • With multiple vaccines for adolescents recommended, it is imperative providers remain up to date with the current recommendations. With misinformation of vaccine safety and effectiveness in the mainstream media and social media, adolescents are a vulnerable population that needs to be reviewed and educated. Adolescents are typically only just starting to take ownership of their health care. Conse…
  • The epidemiology of invasive meningococcal disease and the utility of vaccination in Malta. [Journal Article]
    Eur J Clin Microbiol Infect Dis. 2020 May 16 [Online ahead of print]Pace D, Gauci C, Barbara C
  • Invasive meningococcal disease (IMD) is a vaccine-preventable devastating infection that mainly affects infants, children and adolescents. We describe the population epidemiology of IMD in Malta in order to assess the potential utility of a meningococcal vaccination programme. All cases of microbiologically confirmed IMD in the Maltese population from 2000 to 2017 were analysed to quantify the ov…
  • Meningococcal infections among refugees and immigrants: silent threats of past, present and future. [Journal Article]
    Hum Vaccin Immunother. 2020 Apr 29 [Online ahead of print]Dinleyici EC, Borrow R
  • Globally, there is an increasing number of international migrants. The majority are forced displaced refugees and children unaccompanied by a caregiver, and have limited access to essential public health interventions. Routine vaccination might be interrupted or be incomplete due to conflict areas with limited public health services or a long-unplanned journey. Refugees and migrants may bring inf…
  • Cuban Meningococcal Vaccine VA-MENGOC-BC:30 Years of Use and Future Potential. [Journal Article]
    MEDICC Rev. 2019 Oct; 21(4):19-27.Sierra-González VG
  • Every year, meningococcal infection by Neisseria meningitidis causes over 500,000 cases and 85,000 deaths in the world, with 20% of survivors suffering sequelae. In Cuba its incidence in 1980 reached 5.9 cases per 100,000 population; about 80% of cases were serogroup B, prompting health authorities to declare meningococcal disease the country's main public health problem. Several provinces report…
  • Serogroup a meningococcal conjugate vaccines: building sustainable and equitable vaccine strategies. [Journal Article]
    Expert Rev Vaccines. 2020 Apr 29 [Online ahead of print]Sherman AC, Stephens DS
  • Introduction: For well over 100 years, meningococcal disease due to serogroup A Neisseria meningitidis (MenA) has caused severe epidemics globally, especially in the meningitis belt of sub-Saharan Africa.Areas covered: The article reviews the background and identification of MenA, the global and molecular epidemiology of MenA, and the outbreaks of MenA in the African meningitis belt. The implemen…
  • Vaccines for Older Travelers. [Review]
    Interdiscip Top Gerontol Geriatr. 2020; 43:158-181.Jilg W
  • People who travel to countries where they are at risk of contracting specific infections often need specific vaccines. To make correct recommendations in this respect several points have to be considered. The state of health of the traveler should be known as well as his or her destination and travel style. Very important, however, is the age of the traveler. As advancing age leads to changes in …
  • Meningococcal factor H binding protein as immune evasion factor and vaccine antigen. [Review]
    FEBS Lett. 2020 Apr 16 [Online ahead of print]Principato S, Pizza M, Rappuoli R
  • Factor H binding protein (fHbp) is a key virulence factor of Neisseria meningitidis and a main component of the two licensed vaccines against serogroup B meningococcus (Bexsero and Trumenba). fHbp is a surface-exposed lipoprotein that enables the bacterium to survive in human blood by binding the human complement regulator factor H (fH). When used as vaccine, the protein induces antibodies with p…
  • Protecting the most vulnerable age group: a review of MenACWY-TT immunogenicity and safety in infants. [Journal Article]
    Expert Rev Vaccines. 2020 Apr; 19(4):313-325.Martinón-Torres F, Serra L, Safadi MAP
  • Neisseria meningitidis causes invasive meningococcal disease (IMD), with the highest incidence observed in infants and young children. Meningococcal serogroups A, B, C, W, X, and Y account for almost all IMD cases worldwide. Available meningococcal vaccines targeting serogroups A, C, W, and Y (MenACWY) include those conjugated to diphtheria toxoid (MenACWY-D), diphtheria protein cross-reactive ma…
  • Meningococcal carriage in Norwegian teenagers: strain characterisation and assessment of risk factors. [Journal Article]
    Epidemiol Infect. 2020 Mar 31; 148:e80.Watle SV, Caugant DA, … Næss LM
  • Teenagers have a higher risk of invasive meningococcal disease (IMD) than the general population. This cross-sectional study aimed to characterise strains of Neisseria meningitidis circulating among Norwegian teenagers and to assess risk factors for meningococcal carriage. Oropharyngeal swabs were collected from secondary-school students in southeastern Norway in 2018-2019. Meningococcal isolates…
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