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Unbound Medicine.
(Monkeypox)
2,611 results
  • A case of occupational transmission of mpox. [Journal Article]
    Infection. 2023 Feb 03 [Online ahead of print]Migaud P, Hosmann K, … Stocker H
  • CONCLUSIONS: Mpox can potentially be transmitted in an occupational context. Medical personnel should be informed about this possible route of transmission.
  • Sexual behaviors, cannabis, alcohol and monkeypox infection. [Review]
    Front Public Health. 2022; 10:1054488.Vallée A
  • The emergence of the monkeypox virus (MPXV) outbreak in 2022 is a worldwide health issue. The rapid increase of monkeypox cases caused the WHO to designate the escalating global monkeypox outbreak a Public Health Emergency of International Concern on July 23, 2022. The WHO has called on the group currently most affected by the virus, men who have sex with men (MSM), to limit their sexual partners…
  • Genomic Analysis of Early Monkeypox Virus Outbreak Strains, Washington, United States. [Journal Article]
    Emerg Infect Dis. 2023 Feb 02; 29(3)Roychoudhury P, Sereewit J, … Greninger AL
  • We conducted a genomic analysis of monkeypox virus sequences collected early in the 2022 outbreak, during July-August , in Washington, USA. Using 109 viral genomes, we found low overall genetic diversity, multiple introductions into the state, ongoing community transmission, and potential for co-infections by multiple strains.
  • Possible Mpox Protection from Smallpox Vaccine-Generated Antibodies among Older Adults. [Journal Article]
    Emerg Infect Dis. 2023 Feb 02; 29(3)Sanz-Muñoz I, Sánchez-dePrada L, … Eiros JM
  • Smallpox vaccination may confer cross-protection to mpox. We evaluated vaccinia virus antibodies in 162 persons ≥50 years of age in Spain; 68.5% had detectable antibodies. Highest coverage (78%) was among persons 71-80 years of age. Low antibody levels in 31.5% of this population indicates that addressing their vaccination should be a priority.
  • Monkeypox Infection with primarily mucosal involvement. [Journal Article]
    Sex Transm Dis. 2022 Dec 06 [Online ahead of print]Pestana M, Caldeira MB, … Fernandes C
  • Since May 2022, several non-endemic countries face a monkeypox outbreak, with clinic and epidemiological characteristics distinct from the classic ones. Primarily affecting the sexually active population, these cases present with mucocutaneous lesions mainly localized in perioral, genital, and anal areas. A retrospective study was conducted in a tertiary center in Lisbon, to characterize the popu…
  • Monkeypox-Associated Disciform Keratitis. [Journal Article]
    Cornea. 2022 Dec 09 [Online ahead of print]Alsarhani WK, Chan CC, … Tan DHS
  • CONCLUSIONS: MPX may cause disciform keratitis and scarring that closely resembles other ocular viral infections. Clinical trials are urgently needed to define the optimal management of human MPX infections and reduce vision loss.
  • Monkeypox keratoconjunctivitis with associated Wessley immune ring in an immunocompetent patient. [Letter]
    J Med Virol. 2023 Feb 02 [Online ahead of print]Quites TO, Landeira LFL, … Barroso SPC
  • Monkeypox is a neglected zoonotic disease caused by Monkeypox virus (MPXV), a double-stranded DNA virus of the genus Orthopoxvirus. Here we present a case report of a 32-year-old man with MPXV infection who developed keratoconjunctivitis and Wessley immune ring with no identifiable cause other than ocular involvement by MPXV. We highlight the need of ophthalmologists exploring any ocular symptoms…
  • Monkeypox disease and pregnancy. Where are we today? A review of literature. [Review]
    J Perinatol. 2023 Feb 01 [Online ahead of print]Kopanou Taliaka P, Tsantes AG, … Sokou R
  • Monkeypox has emerged as a significant human pathogen, posing severe risks in vulnerable populations. At present, there is not enough data available as to whether pregnant women are more vulnerable to monkeypox infection, or they suffer more severe symptoms, and studies on this issue as well as to the possible adverse effects on the developing fetus are limited. The aim of this review, was to bri…
  • Gold-based paper for antigen detection of monkeypox virus. [Journal Article]
    Analyst. 2023 Jan 26 [Online ahead of print]Ye L, Lei X, … Xu C
  • In 2022, the outbreak of the monkeypox virus occurred in many non-endemic countries, and the World Health Organization (WHO) assessed that this outbreak was "atypical". The establishment of a rapid and effective assay that can be used for the early diagnosis of monkeypox virus infection is crucial for outbreak prevention and control. In this study, the monkeypox virus A29 protein and the homologo…
  • The Mpox, serious menace, or paper tiger? [Review]
    Iran J Microbiol. 2022 Dec; 14(6):770-777.Jalilian S, Bastani MN
  • One of the most horrible diseases in history, Smallpox is caused by the Variola from Poxvirus family, has caused great morbidity and mortality along the way since it was eradicated in the 20th century. During and after the eradication program for Variola, other Poxviruses such as the Monkeypox (Mpox) virus, which causes a smallpox-like disease, became flagrant. With its long range of enzymes and …
  • Outbreaks of human monkeypox during the COVID-19 pandemic: a systematic review for healthcare professionals. [Review]
    Iran J Microbiol. 2022 Dec; 14(6):778-791.Nagarajan P, Howlader A, … Rangarajalu K
  • The ongoing 2022 multicountry monkeypox epidemic has drawn worldwide attention. Human monkeypox is a virus that spreads from animals to humans. It is an endemic disease in the rain forests of Central and West Africa. However, the disease recently emerged in India, and also in United States through imported wild rodents from Africa, even though the world is still struggling to escape from the clut…
  • Real-world effectiveness of a single dose of mpox vaccine in males. [Journal Article]
    Nat Med. 2023 Jan 31 [Online ahead of print]Sagy YW, Zucker R, … Netzer D
  • The recent global outbreak of the monkeypox (mpox) virus in humans was declared a public health emergency by the World Health Organization in July 2022. The smallpox and mpox vaccine (JYNNEOS; Modified Vaccinia Ankara-Bavarian Nordic; MVA-BN), provided as a two-dose regimen, is currently the primary vaccine utilized against mpox. However, the efficacy of MVA-BN against mpox has never been demonst…
  • Monkeypox virus replication underlying circadian rhythm networks. [Review]
    J Neurovirol. 2023 Jan 31 [Online ahead of print]Zandi M, Shafaati M, … Hashemnia SMR
  • The mammalian brain has an endogenous central circadian clock that regulates central and peripheral cellular activities. At the molecular level, this day-night cycle induces the expression of upstream and downstream transcription factors that influence the immune system and the severity of viral infections over time. In addition, there are also circadian effects on host tolerance pathways. This s…
  • Monkeypox-induced Myocarditis: A Systematic Review. [Review]
    Curr Probl Cardiol. 2023 Jan 27 [Online ahead of print]Jaiswal V, Sultana Q, … Naz S
  • CONCLUSIONS: Our study's findings show that all cases were reported among male patients with the most common symptoms of chest pain. The overall prognosis was good, with no mortality reported. Infected patients complaining of chest pain should not be ignored, and proper investigation of myocarditis must be considered.
  • Case Report: Monkeypox - Not Just a Rash. [Case Reports]
    Am J Trop Med Hyg. 2023 Jan 30 [Online ahead of print]Contag CA, Karan A, … Sahni H
  • Mpox (formally monkeypox) is an Orthopoxvirus associated with both zoonotic and person-to-person spread. Human mpox classically presents with rash and systemic symptoms. Although sporadic outbreaks of mpox have occurred worldwide, the 2022 outbreak is the first of pandemic significance. Thousands of geographically dispersed cases were reported beginning in May 2022. The clinical presentations and…
  • Progression of human monkeypox infection despite tecovirimat in an immunocompromised adult. [Journal Article]
    Transpl Infect Dis. 2023 Jan 30 [Online ahead of print]Dammann F, Raja M, Camargo JF
  • We report a case of an immunocompromised man with monkeypox who experienced disease progression despite timely initiation of tecovirimat and ultimately required utilization of cidofovir and VIGIV for treatment. In immunocompromised patients, monkeypox might present with a more severe course of disease requiring consideration of alternative treatment strategies.
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