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(Mood Disorders)
142,898 results
  • SUMO conjugation as regulator of the glucocorticoid receptor-FKBP51 cellular response to stress. [Review]
    Steroids 2019; :108520Liberman AC, Budziñski ML, … Arzt E
  • In order to adequately respond to stressful stimuli, glucocorticoids (GCs) target almost every tissue of the body. By exerting a negative feedback loop in the hypothalamic-pituitary-adrenal (HPA) axis GCs inhibit their own synthesis and restore homeostasis. GCs actions are mostly mediated by the GC receptor (GR), a member of the nuclear receptor superfamily. Alterations of the GR activity have be…
  • [Sleep, memory and learning]. [Journal Article]
    Medicina (B Aires) 2019; 79 Suppl 3:29-32Acosta MT
  • Recent studies have demonstrated that while we are sleeping, our brain is very busy processing all information we have acquired along the day. Lack of sleep has shown to produce deficits in memory consolidation and plays an important role in brain development and brain plasticity in the several developmental stages of the human brain. At the cellular level, circadian cycles coordinate complex mec…
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