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2,117 results
  • Management of the neck after definitive chemoradiation in patients with HPV-associated oropharyngeal cancer: An institutional experience. [Journal Article]
  • AJAm J Otolaryngol 2019 Jun 12
  • Wotman M, Ghaly M, … Teckie S
  • CONCLUSIONS: This institutional experience supports the notion of a high threshold for neck dissection in this low-risk population; only 1 of 20 patients with suspicious PET/CT findings had residual disease in the neck. Moreover, these patients should be managed by a multidisciplinary tumor board (MTB) since current algorithms do not universally include HPV status. Finally, the use of restaging PET/CT to guide management of the neck can be improved with changes in terminology and consideration of FDG-avidity at the primary site and on pre-therapy scans.
  • PTEN Hamartoma Tumor Syndrome: A Clinical Overview. [Review]
  • CCancers (Basel) 2019 Jun 18; 11(6)
  • Pilarski R
  • The phosphatase and tensin homolog (PTEN) hamartoma tumor syndrome (PHTS) is a grouping of related genetic disorders that has been linked to germline mutations in the PTEN gene. These disorders inclu…
  • Challenges of Providing Concordant Interpretation of Somatic Variants in Non-Small Cell Lung Cancer: A Multicenter Study. [Journal Article]
  • JCJ Cancer 2019; 10(8):1814-1824
  • Gao P, Zhang R, … Li J
  • CONCLUSIONS: Owing to numerous reasons, the interpretation of variants differed greatly, which might in turn lead to the inappropriate clinical care of patients with NSCLC. By analyzing the limitations of different databases used by laboratories, we integrated various types of databases with different levels of evidence to form a comprehensive and detailed variant interpretation pipeline, aiming to standardize the variant classification and provide accurate and sufficient therapeutic drug recommendation to clinicians for minimal-inappropriate therapeutic options.
  • NCCN Guidelines Insights: B-Cell Lymphomas, Version 3.2019. [Journal Article]
  • JNJ Natl Compr Canc Netw 2019 Jun 01; 17(6):650-661
  • Zelenetz AD, Gordon LI, … Sundar H
  • Diffuse large B-cell lymphomas (DLBCLs) and follicular lymphoma (FL) are the most common subtypes of B-cell non-Hodgkin's lymphomas in adults. Histologic transformation of FL to DLBCL (TFL) occurs in…
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