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177,043 results
  • Long-term transcriptional memory in rice plants submitted to salt shock. [Journal Article]
    Planta. 2020 May 30; 251(6) Amaral MN, Arge LWP, … Braga EJB
  • CONCLUSIONS: A first salt shock event alters transcriptional and physiological responses to a second event, being possible to identify 26 genes associated with long-term memory. Soil salinity significantly affects rice cultivation, resulting in large losses in growth and productivity. Studies report that a disturbing event can prepare the plant for a subsequent event through memory acquisition, involving physiological and molecular processes. Therefore, genes that provide altered responses in subsequent events define a category known as "memory genes". In this work, the RNA-sequencing (RNA-Seq) technique was used to analyse the transcriptional profile of rice plants subjected to different salt shock events and to characterise genes associated with long-term memory. Plants subjected to recurrent salt shock showed differences in stomatal conductance, chlorophyll index, electrolyte leakage, and the number of differentially expressed genes (DEGs), and they had lower Na+/K+ ratios than plants that experienced only one stress event. Additionally, the mammalian target of rapamycin (mTOR) pathways, and carbohydrate and amino acid-associated pathways were altered under all conditions. Memory genes can be classified according to their responses during the first event (+ or -) and the second shock event (+ or -), being possible to observe a larger number of transcripts for groups [+ /-] and [-/ +], genes characterised as "revised response." This is the first long-term transcriptional memory study in rice plants under salt shock, providing new insights into the process of plant memory acquisition.
  • The effects of tricaine mesylate on arthropods: crayfish, crab and Drosophila. [Journal Article]
    Invert Neurosci. 2020 May 30; 20(3):10.Stanley CE, Adams R, … Cooper RL
  • Tricaine mesylate, also known as MS-222, was investigated to characterize its effects on sensory neurons, synaptic transmission at the neuromuscular junction, and heart rate in invertebrates. Three species were examined: Drosophila melanogaster, blue crab (Callinectes sapidus), and red swamp crayfish (Procambarus clarkii). Intracellular measures of action potentials in motor neurons of the crayfi…
  • Oxaliplatin-induced peripheral neuropathy: clinical features, mechanisms, prevention and treatment. [Review]
    J Neurol. 2020 May 30 [Online ahead of print]Kang L, Tian Y, … Chen H
  • Oxaliplatin (OXA) is a commonly used platinum-based chemotherapy drug for colorectal cancer. OXA-induced peripheral neurotoxcity (OIPN) is a comprehensive adverse reaction of OXA. OIPN can be divided into acute and chronic types according to clinical features and different mechanisms. The main clinical features of acute OIPN are cold-sensitive sensory symptoms and neuropathic pain in limbs. In ad…
  • Generation and proteome profiling of PBMC-originated, iPSC-derived lentoid bodies. [Journal Article]
    Stem Cell Res. 2020 May 05; 46:101813.Ali M, Kabir F, … Riazuddin SA
  • Here, we report proteome profiling of peripheral blood mononuclear cell (PBMC)-originated, induced pluripotent stem cell (iPSC)-derived, lens-like organoids termed lentoid bodies at two differentiation time points. A small aliquot of the blood sample was ascertained to collect PBMCs that were reprogrammed to iPSCs. The PBMC-originated, iPSCs were differentiated to lentoid bodies employing the "fr…
  • Metal element alteration in the lung by cisplatin and CV247 administration. [Journal Article]
    Biomed Pharmacother. 2020 May 28; 128:110307.Szentmihályi K, Blázovics A, … Máthé C
  • Despite significant nephrotoxicity, cisplatin is still used in the therapy of various tumors. We were interested in how metal ion composition is altered by cisplatin and whether platinum accumulates in the non-tumorous lung. We also aimed to study metal ion changes after treatment with a veterinary medicament CV247 with antioxidant property (containing Cu and Mn gluconate, ascorbic acid, Na salic…
  • Iron-modified rice husk hydrochar and its immobilization effect for Pb and Sb in contaminated soil. [Journal Article]
    J Hazard Mater. 2020 May 20; 398:122977.Teng F, Zhang Y, … Hu D
  • Cationic and anionic heavy metal contamination sometimes co-exists in soil systems, such as mining areas and shooting ranges, seriously threatens human health and ecological stability. In this study, iron-modified rice husk hydrochar showed commendable ability to immobilize both heavy metal cation (Pb) and anion (Sb) simultaneously in soils. Iron-modified rice husk hydrochar (HC12.5-180) (5%) ame…
  • Involvement of activin a receptor type 1 (ACVR1) in the pathogenesis of primary focal hyperhidrosis. [Journal Article]
    Biochem Biophys Res Commun. 2020 May 27 [Online ahead of print]Lin JB, Chen JF, … Kang MQ
  • The pathogenesis of primary focal hyperhidrosis (PFH) is still not clear. PFH is thought to be a genetic disease. Whether activin A receptor type 1 (ACVR1) is involved in the pathogenesis of PFH is unknown. In this study, the expression of ACVR1 in sweat glands of patients with PAH was detected by western blot and immunofluorescence. The primary sweat gland cells obtained from primary axillary hy…
  • Chemical characterization and source apportionment of ambient nanoparticles: a case study in Hanoi, Vietnam. [Journal Article]
    Environ Sci Pollut Res Int. 2020 May 29 [Online ahead of print]Nghiem TD, Nguyen TTT, … Duong TN
  • PM0.1 has been believed to have adverse short- and long-term effects on human health. However, the information of PM0.1 that is needed to fully evaluate its influence on human health and environment is still scarce in many developing countries. This is a comprehensive study on the levels, chemical compositions, and source apportionment of PM0.1 conducted in Hanoi, Vietnam. Twenty-four-hour sample…
  • Evaluation of the Carbon Dioxide Production by Fungi Under Different Growing Conditions. [Journal Article]
    Curr Microbiol. 2020 May 29 [Online ahead of print]Pavlík M, Fleischer P, … Šuleková M
  • Production of carbon dioxide, as one of the ultimate products of fungal metabolism, can be used to quantify and measure their metabolic rate under different conditions, thus aiding in finding the optimal substrate and environment for cultivation of wood-destroying fungi. This study is focused on species Pleurotus ostreatus and Ganoderma lucidum,. These species are also cultivated for mycorestorat…
  • Enzymatically hardened calcium phosphate biocement with phytic acid addition. [Journal Article]
    J Mater Sci Mater Med. 2020 May 29; 31(6):54.Medvecky L, Stulajterova R, … Koval K
  • Novel enzymatically hardened tetracalcium phosphate/monetite cements were prepared applying phytic acid/phytase (PHYT/F3P) mixture as hardening liquid after dissolving in acetic acid solution (CX cement). Properties of the cements were compared with classic cement hardened with 2% NaH2PO4 (C cement) and cement hardened with acetic acid solution (CAC cement) only. In the microstructure of CX cemen…
  • BEAVR: a browser-based tool for the exploration and visualization of RNA-seq data. [Journal Article]
    BMC Bioinformatics. 2020 May 29; 21(1):221.Perampalam P, Dick FA
  • CONCLUSIONS: BEAVR simplifies analysis for novice users but also streamlines the RNA-seq analysis process for experts by automating several steps. BEAVR and its documentation can be found on GitHub at BEAVR is available as a Docker container at
  • More that unites us than divides us? A qualitative study of integration of community health and social care services. [Journal Article]
    BMC Fam Pract. 2020 May 29; 21(1):96.Mitchell C, Tazzyman A, … Hodgson D
  • CONCLUSIONS: Given the long-term national policy focus on integration this ambitious approach to integrate community health and social care has highlighted implications for leadership, organisational design and inter-professional working. Given the ethos of valuing the local assets of individuals and networks within the new partnership we found the integrated neighbourhood teams could all learn from each other. Many of the challenges of integration could benefit from embracing the inherent capabilities across the integrated neighbourhood teams and localities of this city.
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