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1,313 results
  • Naegleria Fowleri: sources of infection, pathophysiology, diagnosis, and management; a review. [Review]
    Clin Exp Pharmacol Physiol 2019Jahangeer M, Mahmood Z, … Zainab R
  • Naegleria fowleri,athermophilic flagellateamoeba known as "brain-eating" amoeba, is the etiologicalagent of perilous and devastating waterborne disease known asPrimary amoebicmeningoencephalitis (PAM) both in human as well as in animals.PAM is a rare but fatal disease affecting young adults all around the world,particularlyin the developed worldbut recentlyreported from developing countries, with…
  • Primary amoebic meningoencephalitis in an infant. [Case Reports]
    Indian J Med Microbiol 2019 Jan-Mar; 37(1):120-122Mittal N, Mahajan L, … Khurana S
  • Primary amoebic meningoencephalitis is rare but fatal disease encountered in immunocompetent individuals. Here, we present a case of a previously healthy 8-month-old female child, who presented with features of meningoencephalitis of 2 days' duration. Rapidly moving trophozoites of amoeba were observed in cerebrospinal fluid, which were confirmed to be Naegleria fowleri on polymerase chain reacti…
  • Host Invasion by Pathogenic Amoebae: Epithelial Disruption by Parasite Proteins. [Review]
    Genes (Basel) 2019; 10(8)Betanzos A, Bañuelos C, Orozco E
  • The epithelium represents the first and most extensive line of defence against pathogens, toxins and pollutant agents in humans. In general, pathogens have developed strategies to overcome this barrier and use it as an entrance to the organism. Entamoeba histolytica, Naegleria fowleri and Acanthamoeba spp. are amoebae mainly responsible for intestinal dysentery, meningoencephalitis and keratitis,…
  • In Vitro Activity of Statins against Naegleria fowleri. [Journal Article]
    Pathogens 2019; 8(3)Rizo-Liendo A, Sifaoui I, … Lorenzo-Morales J
  • Naegleria fowleri causes a deadly disease called primary amoebic meningoencephalitis (PAM). Even though PAM is still considered a rare disease, the number of reported cases worldwide has been increasing each year. Among the factors to be considered for this, awareness about this disease, and also global warming, as these amoebae thrive in warm water bodies, seem to be the key factors. Until prese…
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