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10 results
  • Novel oral contraceptive for heavy menstrual bleeding: estradiol valerate and dienogest. [Journal Article]
    Int J Womens Health 2013; 5:313-21Rafie S, Borgelt L, … Lehman KJ
  • Abnormal uterine bleeding (AUB) is associated with significant direct medical costs and impacts both society and the quality of life for individual women. Heavy menstrual bleeding, a subset of AUB, also referred to as menorrhagia, is defined as menstrual blood loss greater than 80 mL or the patient's perception of excessive blood loss. The newest treatment option available is a novel combination …
  • Pharmaceutical approval update. [Journal Article]
    P T 2012; 37(7):392-4Goldenberg MM
  • Tazarotene (Fabior Foam) for acne; estradiol valerate and estradiol valerate/dienogest (Natazia) for heavy menstrual bleeding; and taliglucerase alfa (Elelyso) for Gaucher's disease.
  • Estradiol valerate/dienogest: a novel combined oral contraceptive. [Review]
    Clin Ther 2012; 34(1):37-55Borgelt LM, Martell CW
  • CONCLUSIONS: Estradiol valerate/dienogest is a new contraceptive formulation. It offers efficacy, tolerability, and an acceptable safety profile with a potentially better bleeding pattern than levonorgestrel-containing COCs. This COC may be especially useful for older women of reproductive age who are adherent to therapy and looking for shorter and/or lighter menstrual cycles. Studies will need to be performed to determine whether clinically significant differences in outcomes exist among E2V/DNG and other available COCs.
  • Estradiol valerate/dienogest: a novel oral contraceptive. [Review]
    Ann Pharmacother 2011; 45(10):1256-61Whalen KL, Rose R
  • CONCLUSIONS: Estradiol valerate/dienogest is an effective oral contraceptive. Because it has more stringent start times and requires a longer duration of backup contraception and stricter adherence, estradiol valerate/dienogest should be reserved for patients who are intolerant of other combination oral contraceptives.
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