- Acute dacryocystitis complicated by orbital cellulitis and loss of vision: A case report and review of the literature. [Journal Article]
- IJInt J Surg Case Rep 2018 Aug 09; 50:130-134
- CONCLUSIONS: Typically, orbital cellulitis responds well to systemic antibiotic and surgical drainage without permanent visual loss. There are 7 cases reported in the literature of acute dacryocystitis complicated by permanent visual loss.Patients with acute dacryocystitis need to be carefully monitored for signs of orbital cellulitis. Prompt recognition and appropriate treatment of this condition are essential.
- Skin Infections. [Review]
- PCPrim Care 2018; 45(3):433-454
- The primary care provider will commonly see skin and soft tissue infections in the outpatient setting. Skin and soft tissue infections range from the uncomplicated impetigo to the potentially lethal ...
The primary care provider will commonly see skin and soft tissue infections in the outpatient setting. Skin and soft tissue infections range from the uncomplicated impetigo to the potentially lethal necrotizing fasciitis. This article reviews these infections based on their underlying etiology: bacterial, fungal, and viral causes. This article discusses the etiology, presentation, evaluation, and management of impetigo, bullous impetigo, erysipelas, cellulitis, periorbital cellulitis, orbital cellulitis, folliculitis, furuncles, carbuncles, abscess, necrotizing fasciitis, sporotrichosis, tinea corporis, tinea pedis, tinea capitis, Herpes Simplex Virus, zoster, molluscum contagiosum, and warts.
- The activation of the oxidative stress response transcription factor SKN-1 in Caenorhabditis elegans by mitis group streptococci. [Journal Article]
- PlosPLoS One 2018; 13(8):e0202233
- The mitis group, a member of the genetically diverse viridans group streptococci, predominately colonizes the human oropharynx. This group has been shown to cause a wide range of infectious complicat...
The mitis group, a member of the genetically diverse viridans group streptococci, predominately colonizes the human oropharynx. This group has been shown to cause a wide range of infectious complications in humans, including bacteremia in patients with neutropenia, orbital cellulitis and infective endocarditis. Hydrogen peroxide (H2O2) has been identified as a virulence factor produced by this group of streptococci. More importantly, it has been shown that Streptococcus oralis and S. mitis induce epithelial cell and macrophage death via the production of H2O2. Previously, H2O2 mediated killing was observed in the nematode Caenorhabditis elegans in response to S. oralis and S. mitis. The genetically tractable model organism C. elegans is an excellent system to study mechanisms of pathogenicity and stress responses. Using this model, we observed rapid H2O2 mediated killing of the worms by S. gordonii in addition to S. mitis and S. oralis. Furthermore, we observed colonization of the intestine of the worms when exposed to S. gordonii suggesting the involvement of an infection-like process. In response to the H2O2 produced by the mitis group, we demonstrate the oxidative stress response is activated in the worms. The oxidative stress response transcription factor SKN-1 is required for the survival of the worms and provides protection against H2O2 produced by S. gordonii. We show during infection, H2O2 is required for the activation of SKN-1 and is mediated via the p38-MAPK pathway. The activation of the p38 signaling pathway in the presence of S. gordonii is not mediated by the endoplasmic reticulum (ER) transmembrane protein kinase IRE-1. However, IRE-1 is required for the survival of worms in response to S. gordonii. These finding suggests a parallel pathway senses H2O2 produced by the mitis group and activates the phosphorylation of p38. Additionally, the unfolded protein response plays an important role during infection.
- Scleritis, keratitis, and orbital cellulitis: isolated ocular manifestation of systemic lupus erythematosus. [Journal Article]
- LLupus 2018 Aug 09; :961203318792365
- Systemic autoimmune diseases are associated with ocular inflammatory conditions such as episcleritis, scleritis, keratitis, and uveitis. However, ocular manifestations have been reported to correlate...
Systemic autoimmune diseases are associated with ocular inflammatory conditions such as episcleritis, scleritis, keratitis, and uveitis. However, ocular manifestations have been reported to correlate with the extent of systemic disease. We present a patient with scleritis, keratitis, and orbital cellulitis, as the isolated manifestation of systemic lupus erythematosus (SLE). No microbial etiology was identified and antibiotics did not produce clinical improvement. The patient improved significantly with steroids and disease-modifying antirheumatic drugs. Although ocular inflammation has been previously remarked in SLE of systemic severity, in this case there were no other organs with SLE involvement. We briefly discuss the ocular manifestations of SLE, which can involve all segments of the eye, including cornea, sclera, retina, uvea, optic nerve, and orbit.
- Extra-Ocular Cysticercosis Mimicking Orbital Cellulitis. [Journal Article]
- JCJ Coll Physicians Surg Pak 2018; 28(8):654-655
- Isolated left upper eyelid ptosis with pansinusitis and contralateral otitis media in a 9-year-old boy. [Journal Article]
- AJAm J Ophthalmol Case Rep 2018; 11:6-9
- CONCLUSIONS: This finding on imaging disclosed the etiology of an otherwise unexplained case of upper lid ptosis.
- Impact of superior ophthalmic vein thrombosis: a case series and literature review. [Journal Article]
- OOrbit 2018 Jul 24; :1-7
- CONCLUSIONS: Our case series and literature review show that SOVT can occur simultaneously with cavernous sinus thrombosis (CST) but can also be a separate entity. Clinical presentation can mimic orbital cellulitis (OC) or CST and when no signs of OC can be found, an alternative cause for SOVT should be sought. When timely and adequate treatment is conducted, the prognosis is predominantly favourable.
- [Periorbital, blue tumour in newborn twins]. [Journal Article]
- NTNed Tijdschr Geneeskd 2018 Jul 13; 162
- Newborn twins both had a blue, smooth tumour in the inner angle of the orbit; one of them had two such tumours. They were diagnosed with congenital dacryocystoceles. If decompression into the nose is...
Newborn twins both had a blue, smooth tumour in the inner angle of the orbit; one of them had two such tumours. They were diagnosed with congenital dacryocystoceles. If decompression into the nose is not effective, patients should undergo probing early in life to reduce the incidence of dacryocystitis and orbital cellulitis.
- Ocular Basidiobolomycosis: A Case Report. [Journal Article]
- CRCase Rep Ophthalmol 2018 May-Aug; 9(2):315-321
- CONCLUSIONS: B. ranarum is a rare pathogen of ocular infection in which a definite diagnosis requires isolation of the causative organism. Delay in diagnosis and appropriate treatment can lead to extension of the infection and poor outcomes.
New Search Next
- StatPearls [BOOK]
- BOOKStatPearls Publishing: Treasure Island (FL)
- Orbital cellulitis is an infection causing inflammation of the orbital contents posterior to the orbital septum. These contents include the periorbital fat and extra-ocular muscles, but exclude the i...
Orbital cellulitis is an infection causing inflammation of the orbital contents posterior to the orbital septum. These contents include the periorbital fat and extra-ocular muscles, but exclude the involvement of the globe itself. In distinction, preseptal (periorbital) cellulitis is an infection anterior to the orbital septum, mainly involving the eyelids. Although periorbital cellulitis is a much more common entity, especially in children, it is important to recognize the differences of orbital cellulitis as its complications are much more severe and can become life-threatening.