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(Oseltamivir AND ("Novel Coronavirus" OR COVID-19 OR SARS-CoV-2 OR 2019-nCoV))
268 results
  • A MOF/DNA luminescent sensing platform for detection of potential COVID-19 biomarkers and drugs. [Journal Article]
    Chem Sci. 2023 May 24; 14(20):5386-5395.Wang X, Clavier G, … Serre C
  • COVID-19 has afflicted people's lives worldwide. Interleukin-6 (IL-6) is an important COVID-19 biomarker in human body fluids that can be used as a reference to monitor COVID-19 in real-time and therefore to reduce the risk of virus transmission. On the other hand, oseltamivir is a potential COVID-19 curing drug, but its overuse easily leads to hazardous side effects, calling for its real time mo…
  • Stability and WBE biomarkers possibility of 17 antiviral drugs in sewage and gravity sewers. [Journal Article]
    Water Res. 2023 Jun 30; 238:120023.Wen J, Duan L, … Yu G
  • Wastewater-based epidemiology (WBE) is a promising technique for monitoring the rapidly increasing use of antiviral drugs during the COVID-19 pandemic. It is essential to evaluate the in-sewer stability of antiviral drugs in order to determine appropriate biomarkers. This study developed an analytical method for quantification of 17 typical antiviral drugs, and investigated the stability of targe…
  • Clinical misdiagnosis of influenza infection with a confusing clinical course: A case report. [Case Reports]
    Clin Case Rep. 2023 Apr; 11(4):e7196.Babazadeh A, Mohseni Afshar Z, … Ebrahimpour S
  • A 32-year-old woman with a history of hypothyroidism and major depressive disorder was admitted with severe weakness and somnolence. She had tachycardia and hypotension, indicative of severe dehydration, and was treated with a vasopressor and sodium bicarbonate, but her clinical manifestations deteriorated. A high-resolution computed tomography (HRCT) scan showed a patchy ground glass appearance …
  • Influenza in Liver and Kidney Transplant Recipients: Incidence and Outcomes. [Journal Article]
    Microbiol Spectr. 2023 Mar 28 [Online ahead of print]Arentoft NS, Møller DL, … Nielsen SD
  • Influenza is a common respiratory tract infection in solid organ transplant (SOT) recipients. We aimed to investigate the incidence, risk factors, and complications of influenza in a large cohort of kidney and liver transplant recipients over 10 consecutive seasons. We conducted a retrospective study, including 378 liver and 683 kidney transplant recipients who were transplanted from January 1, 2…
  • Antiviral therapies for influenza. [Review]
    Curr Opin Infect Dis. 2023 04 01; 36(2):124-131.Chan KKP, Hui DSC
  • The heavily suppressed global influenza activity during the coronavirus disease 2019 (COVID-19) pandemic is expected to return upon relaxation of travel restriction and nonpharmaceutical interventions (NPI). We reviewed the four marketed neuraminidase inhibitors (NAI e.g., oseltamivir, zanamivir, peramivir, laninamivir) and the only endonuclease inhibitor (baloxavir) on their clinical therapeutic…
  • Assessment of influenza A (H1N1, H3N2) oseltamivir resistance during 2017-2019 in Iran. [Journal Article]
    Iran J Microbiol. 2022 Aug; 14(4):545-553.Gholami A, Shafiei-Jandaghi NZ, … Mokhtari-Azad T
  • CONCLUSIONS: Evaluation of NA gene sequences, showed no resistant viruses to oseltamivir. Given that the viruses in the present study were the last viruses circulating in Iran before COVID-19 pandemic, the results will be beneficial to have a worthy comparison with the strains circulating after the pandemic. Constant monitoring for the emergence of drug-resistant variants and antigenic changes are crucial for all countries.
  • Treatment of Hydatidiform Mole Suspected to COVID 19. [Case Reports]
    Adv Biomed Res. 2022; 11:105.Azarkish F, Rigiyousefabadi S, … Kashani ZA
  • The aim of this study was to report a case of the treatment of hydatidiform mole in Coronavirus pandemic in Iranshahr. A 17-year-old primiparous woman with gestational age of 14 weeks presented with unilateral leg swelling and sudden abdominal distension beginning in the night before referring to the health center. In the abdominal examination of the patient by a healthcare provider, the baby's h…
  • Preparing for pandemics: a systematic review of pandemic influenza clinical management guidelines. [Systematic Review]
    BMC Med. 2022 11 07; 20(1):425.Rigby I, Michelen M, … Sigfrid L
  • CONCLUSIONS: Our data highlights the limited availability of up-to-date pandemic influenza CMGs globally. Of those identified, many were limited in scope and quality and several lacked recommendations for specific at-risk populations. Recommendations on supportive care, the mainstay of treatment, were limited and heterogeneous. The most recent guideline highlighted that the evidence-base to support antiviral treatment recommendations is still limited. There is an urgent need for trials into treatment and supportive care strategies including for different risk populations. New evidence should be incorporated into globally accessible guidelines, to benefit patient outcomes. A 'living guideline' framework is recommended and further research into guideline implementation in different resourced settings, particularly low- and middle-income countries.
  • Deep learning in drug discovery: a futuristic modality to materialize the large datasets for cheminformatics. [Review]
    J Biomol Struct Dyn. 2022 Oct 28 [Online ahead of print]Raza A, Chohan TA, … Murtaza G
  • Artificial intelligence (AI) development imitates the workings of the human brain to comprehend modern problems. The traditional approaches such as high throughput screening (HTS) and combinatorial chemistry are lengthy and expensive to the pharmaceutical industry as they can only handle a smaller dataset. Deep learning (DL) is a sophisticated AI method that uses a thorough comprehension of parti…
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