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(Osmolar gap)
376 results
  • Formulas for Calculated Osmolarity and Osmolal Gap: A Study of Diagnostic Accuracy. [Journal Article]
  • AJAm J Kidney Dis 2017; 70(3):347-356
  • Lepeytre F, Ghannoum M, … Bouchard J
  • CONCLUSIONS: Single center, no external validation, limited number of cases with detectable toxic alcohols.In a large cohort, coefficients from regression analyses estimating the contribution of glucose, urea, and ethanol were higher than 1.0. Our simplified formula to precisely calculate osmolarity yielded improved diagnostic accuracy for suspected toxic alcohol exposures than previously published formulas.
  • Serum osmolal gap in clinical practice: usefulness and limitations. [Review]
  • PMPostgrad Med 2017; 129(4):456-459
  • Liamis G, Filippatos TD, … Elisaf MS
  • CONCLUSIONS: The definition and the best formula used for the calculation of osmolal gap, the main causes of increased osmolal gap with or without increased anion gap metabolic acidosis, as well as the role of concurrent lactic acidosis or ketoacidosis are presented under a clinical point of view.The calculation of osmolal gap is crucial in the differential diagnosis of many patients presenting in emergency departments with possible drug or substance overdose as well as in comatose hospitalized patients.
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