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(Ovarian tumor )
99,467 results
  • Dynamics of the Intratumoral Immune Response during Progression of High-Grade Serous Ovarian Cancer. [Journal Article]
  • NNeoplasia 2018 Feb 18; 20(3):280-288
  • Stanske M, Wienert S, … Darb-Esfahani S
  • CONCLUSIONS: This is the first study that analyzed the development of TILs density and MHC expression in paired primary and recurrent HGSOC. The level of the antitumoral immune response in recurrent tumors was clearly dependent on the one in the primary tumor. Our data contribute to the understanding of temporal heterogeneity of HGSOC immune microenvironment and have implications for selection of samples for biomarker testing in the setting of immune-targeting therapeutics.
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