- Victor Horsley's contribution to the Foster Kennedy Syndrome. [Journal Article]
- BJBr J Neurosurg 2004; 18(4):371-374
- Although Foster Kennedy is the name given to the syndrome localizing an intracranial tumour with respect to papilloedema, it is important to recognize how Victor Horsley was one of the strongest prop...
Although Foster Kennedy is the name given to the syndrome localizing an intracranial tumour with respect to papilloedema, it is important to recognize how Victor Horsley was one of the strongest proponents in the usefulness of that sign. Not only did he describe the constellation of findings before Kennedy did, he was also probably one of the people who had influenced Kennedy the most during the latter's time at the National Hospital for Nervous Diseases at Queen Square. It is therefore appropriate that Victor Horsley's characterization in 1910 of the findings that were later recorded as the Foster Kennedy syndrome, and that his altruistic encouragement of Kennedy's publication of the findings, receive recognition and appreciation in the medical and historical community.
- Primary intracranial choriocarcinoma presenting as a ring-enhancing lesion: A case report and review of literature. [Journal Article]
- AJAsian J Neurosurg 2017 Jan-Mar; 12(1):85-88
- We report here a rare case of primary intracranial choriocarcinoma without evidence of tumor elsewhere, presenting as a ring-enhancing lesion managed successfully in our institute (Grant Medical Coll...
We report here a rare case of primary intracranial choriocarcinoma without evidence of tumor elsewhere, presenting as a ring-enhancing lesion managed successfully in our institute (Grant Medical College and Sir J. J. Group of Hospitals, Mumbai, Maharashtra, India). A 22-year-old, right-handed housewife presented with complaints of headache, vomiting, generalized tonic-clonic seizures, and right upper limb weakness of short duration. On neurological examination, the patient was conscious, cooperative, well-oriented in time, place, and person. Visual acuity was 6/9 in both eyes. Fundus was showing grade 1 papilledema. Tone was increased on the right side. Power was decreased in the right upper limb as compared to the left. Reflexes were brisk in the right upper limb. Imaging was suggestive of a thick ring-enhancing lesion in the left parietal region suggestive of glioma or tuberculosis. Complete excision of the lesion was achieved. The diagnosis was confirmed by histopathologic examination of the lesion and β-human chorionic gonadotropin (β-HCG) levels. The patient recovered well postoperatively without neurological deficit. She was relieved of headache completely and there were no further episodes of vomiting or seizures. The right upper limb weakness improved to 4+/5. Choriocarcinoma is the most malignant lesion of all the gestational trophoblastic diseases. Primary brain choriocarcinoma presenting as a ring-enhancing lesion has not been reported in the literature. This diagnosis should be kept in mind, especially in young females of child-bearing age group. Complete surgical excision with adjunctive treatment is required to achieve prolonged remissions.
- Bilateral optic disc drusen mimicking papilloedema. [Editorial]
- PNPract Neurol 2017 Apr 12
- Relationship between lamina cribrosa displacement and trans-laminar pressure difference in papilledema. [Journal Article]
- GAGraefes Arch Clin Exp Ophthalmol 2017 Apr 08
- CONCLUSIONS: LC position was significantly related to TLCD in papilledema. Eyes with higher TCLD showed significantly larger backward LC movement, BMO shrinking and RNFL thinning after lowering CSFP compared with eyes with lower TLCD, where LC movement occurred in the opposite direction.
- Intestinal and neurological involvement in Behcet disease: a clinical case. [Journal Article]
- IJItal J Pediatr 2017 Apr 07; 43(1):33
- CONCLUSIONS: This case report is one of the few described in literature with simultaneous involvement of the two systems, neurological and gastrointestinal tract, in paediatric BD. The diagnosis is really difficult because there is no specific diagnostic test. We think that our clinical case should help clinicians to suspect a BD with an unusual onset.
- Papilledema in children with hydrocephalus: incidence and associated factors. [Journal Article]
- JNJ Neurosurg Pediatr 2017 Apr 07; :1-5
- CONCLUSIONS: Papilledema was more common in patients who were older, who had higher ICP, and whose hydrocephalus had been induced by brain tumor. However, since papilledema was absent in 41% of the children with hydrocephalus, papilledema's absence does not ensure the absence of hydrocephalus, especially in younger patients.
- Outcomes of endoscopic optic nerve decompression in patients with idiopathic intracranial hypertension. [Journal Article]
- IFInt Forum Allergy Rhinol 2017 Apr 06
- CONCLUSIONS: EOND appears to be a promising and safe surgical alternative for patients with IIH who fail to respond to medical treatment. Further studies are needed before we can attest to the clinical validity of this procedure.
- Lesson of the month 2: A choroid plexus papilloma manifesting as anorexia nervosa in an adult. [Journal Article]
- CMClin Med (Lond) 2017; 17(2):183-185
- A Caucasian female previously diagnosed with anorexia nervosa was referred by psychiatric services to the general medical team. She presented with dehydration, vomiting, weakness, a body mass index o...
A Caucasian female previously diagnosed with anorexia nervosa was referred by psychiatric services to the general medical team. She presented with dehydration, vomiting, weakness, a body mass index of 13 kg/m(2) and was treated with intravenous and enteral supplementation. During admission her vomiting worsened and she developed visual hallucinations and confabulation. Neurological examination demonstrated cerebellar signs and bilateral papilloedema on fundoscopy. Subsequent magnetic resonance imaging of the brain revealed a large fourth ventricular tumour causing obstructive hydrocephalus. The tumour was excised and histologically confirmed to be a choroid plexus papilloma. Postoperatively her neurological symptoms and negative feelings towards eating resolved.
- Intracanalicular Optic Nerve Swelling and Signal Change in Fulminant Untreated Idiopathic Intracranial Hypertension. [Journal Article]
- NNeuroophthalmology 2017; 41(2):84-89
- The role of the optic canal in the pathogenesis of papilloedema has been under scrutiny recently. Whether a larger canal precedes more severe papilloedema or is the result of bone remodelling from ch...
The role of the optic canal in the pathogenesis of papilloedema has been under scrutiny recently. Whether a larger canal precedes more severe papilloedema or is the result of bone remodelling from chronically raised pressure across a pressure gradient is not clear. The authors present the magnetic resonance imaging findings of a 29-year-old female with fulminant and untreated idiopathic intracranial hypertension. Imaging showed focal expansion and intrinsic signal changes of the intracanalicular optic nerve. The authors discuss the possibility of either fluid accumulation within the optic nerves from a water hammer effect across blocked optic canals resulting from the steep pressure gradient or opticomalacia (optic nerve softening) from chronic ischaemia.
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- Bilateral haemorrhagic papilloedema secondary to carboplatin use. [Letter]
- NNeurologia 2017 Mar 22