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(Parasites involving the lung)
90 results
  • First report of systemic toxoplasmosis in a New Zealand sea lion (Phocarctos hookeri). [Case Reports]
  • NZN Z Vet J 2017; 65(1):46-50
  • Roe WD, Michael S, … Howe L
  • CONCLUSIONS: Infection with T. gondii involving the spinal cord and nerves was the likely cause of the paresis observed in this sea lion before death. Ultimately, death was attributed to crushing and asphyxiation by a male sea lion, presumably predisposed by impaired mobility. Diagnosis of toxoplasmosis in a New Zealand sea lion highlights the possibility that this disease could play a role in morbidity and mortality in this endangered species, particularly in the recently established mainland populations that are close to feline sources of T. gondii oocysts.
  • Increased expression of upstream TH2-cytokines in a mouse model of viral-induced asthma exacerbation. [Journal Article]
  • JTJ Transl Med 2016 Feb 16; 14:52
  • Mahmutovic Persson I, Akbarshahi H, … Uller L
  • CONCLUSIONS: We demonstrate several novel aspects of HDM-induced experimental asthma and added exacerbation effects of dsRNA. General inflammatory parameters in BALF such as exuded proteins, mixed granulocytes, LDH and ATP were increased at the present exacerbations as they are in human asthma exacerbations. We suggest that this model of asthma exacerbation involving dsRNA challenges given to mice with established HDM-induced asthma has translational value and suggest that it may be particularly suited for in vivo studies involving pharmacological effects on exacerbation-induced expression of major upstream TH2-cytokines; IL-33, TSLP and IL-25, as well as PRRs.
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