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78,037 results
  • Genetic variants related to urate and risk of Parkinson's disease. [Journal Article]
  • PRParkinsonism Relat Disord 2018 May 01
  • Hughes KC, Gao X, … Ascherio A
  • CONCLUSIONS: Our results do not support an association between genetic variants associated with circulating urate levels and risk of PD, but larger investigations are needed to determine whether the modest genetic effects on blood urate contribute to predict PD risk.
  • Possible multiple system atrophy with predominant parkinsonism in a patient with chronic schizophrenia: a case report. [Journal Article]
  • BPBMC Psychiatry 2018 May 21; 18(1):141
  • Komatsu H, Kato M, … Kakuto Y
  • CONCLUSIONS: This case report highlights the importance of considering MSA-P in the differential diagnosis for parkinsonism in a patient being treated with antipsychotics for chronic schizophrenia. MSA-P should be considered in patients presenting with worsening and progressing parkinsonism, especially when accompanied by autonomic dysfunction or cerebellar ataxia. Although a definite diagnosis of MSA-P requires autopsy confirmation, a combination of brain magnetic resonance imaging and nuclear medicine scans may help to differentiate suspected MSA-P from the other parkinsonian syndromes. This case also demonstrates that MSA with parkinsonism that is poorly responsive to L-dopa may improve shortly after modified electroconvulsive therapy without worsening psychiatric symptoms.
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