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(Pregnancy AND thyroid disease in)
9,466 results
  • Diagnostic Overshadowing: Insidious Neuroregression Mimicking Presentation of Autism Spectrum Disorder. [Journal Article]
    J Dev Behav Pediatr. 2022 Jul 04 [Online ahead of print]Loo KK, Cheng J, … Nyp SS
  • Zac is a 13-year-old boy who presented with his parents to developmental-behavioral pediatrics seeking diagnostic clarity. He was born by vaginal delivery at full term after an uncomplicated pregnancy. Developmental milestones were met at typical ages until he was noted to have language delay and to be hyperactive and impulsive on entering preschool at age 4 years. Although he used some phrases i…
  • Congenital hypothyroidism after newborn screening program reorganization in the Apulia region. [Journal Article]
    Ital J Pediatr. 2022 Jul 29; 48(1):131.Simonetti S, D'Amato G, … Faienza MF
  • CONCLUSIONS: The results of these study show an increase of CH cases in newborns with an eutopic thyroid compared to the traditional classification. The centralization of the screening program allows a closer cooperation between laboratory and clinical centers and facilitates the implementation of appropriate diagnostic evaluations and timely initiation of treatment, with positive effects on the management of the condition.
  • Prolonged APTT and autoimmune overt hypothyroidism identified postpartum: a case report. [Case Reports]
    Eur Thyroid J. 2022 Aug 01; 11(4)Hjelm Lundgaard M, Carlé A, … Andersen SL
  • CONCLUSIONS: In this case, prolonged APTT provided a diagnostic clue for the assessment of thyroid function in a young woman with a recent history of severe placental dysfunction. The identification of autoimmune, overt hypothyroidism emphasizes that measurement of TSH may be of clinical importance in cases of unexplained prolonged APTT or other biochemical signs of abnormalities in the coagulation system.
  • Mitral valve chord rupture in a pregnant patient with uncontrolled hyperthyroidism. [Journal Article]
    Endocrinol Diabetes Metab Case Rep. 2022 Jul 01; 2022Fox T, Akhtar H, … Anastasopoulou C
  • Graves' disease can have multiple cardiac manifestations. A rare complication is that of severe mitral regurgitation secondary to mitral valve chordae rupture, due to both compromise of valve integrity by deposition of glycosaminoglycans and the hemodynamic stresses of thyrotoxicosis. Pregnancy, with its related hemodynamic changes, is another setting in which mitral valve chordae rupture has occ…
  • Late offspring effects of antenatal thyroid screening. [Journal Article]
    Br Med Bull. 2022 Jul 23 [Online ahead of print]Panagiotou G, Taylor PN, … Okosieme OE
  • CONCLUSIONS: A small number of studies have shown inconsistent associations of maternal thyroid dysfunction with offspring cardiometabolic indices including blood pressure and body weight. Correction of maternal thyroid dysfunction was, however, associated with favourable long-term metabolic profiles in mothers, including lipid profiles, fat mass and body mass index. Antenatal thyroid screening may therefore present opportunities for optimizing a wider range of outcomes than envisaged.Future trials with early antenatal thyroid screening and intervention are necessary to clarify the impact of screening on late offspring and maternal effects.
  • Experimental data on lithium salts: From neuroprotection to multi-organ complications. [Review]
    Life Sci. 2022 Jul 16; 306:120811.Kakhki S, Ahmadi-Soleimani SM
  • Lithium-salts stand on the first line of therapy for the management of specific psychiatric conditions, mainly bipolar mood disorder. It is also known to protect the brain against neurodegenerative processes such as Alzheimer's disease. Despite the mentioned merits, recent studies have revealed that high dose or prolonged lithium intake deteriorate the function of multiple key organs including he…
  • Endocrine Autoimmunity in Pregnancy. [Review]
    Front Immunol. 2022; 13:907561.Świątkowska-Stodulska R, Berlińska A, … Sworczak K
  • Human gestation leads to a number of physiological alterations which peak at the development of placentta known for, among many other functions, being a transient but highly potent endocrine organ. Hormonal activity of placenta is marked by its ability to continuously produce and secrete high levels of progesterone. Progesterone guards the well-being of the fetoplacental unit throughout the gesta…
  • Further understanding of thyroid function in pregnant women. [Journal Article]
    Expert Rev Endocrinol Metab. 2022 Jul; 17(4):365-374.Ilias I, Milionis C, Koukkou E
  • Normal thyroid status throughout pregnancy is important for both maternal and fetal health. Despite the bulk of contemporary research honing on thyroid function in gestation and the relevant disorders, there are still gaps in our current knowledge about the etiology and treatment of thyroid diseases in pregnant women.
  • Just an Acute Pulmonary Edema? Paraneoplastic Thyroid Storm Due to Invasive Mole. [Case Reports]
    Case Rep Oncol. 2022 May-Aug; 15(2):566-572.Jiménez-Labaig P, Mañe JM, … López-Vivanco G
  • Hydatidiform mole is a malignant entity included in the gestational trophoblastic diseases. It usually produces pregnancy hormones such as beta-human chorionic gonadotropin (β-hCG), which in turn stimulates endogenous thyroid hormone production. We report the case of a high-risk complete invasive hydatidiform mole with pulmonary metastasis and associated paraneoplastic syndrome. The patient is a …
  • Insight Into Mouse Models of Hyperthyroidism. [Review]
    Front Endocrinol (Lausanne). 2022; 13:929750.Zhang M, Jiang W, … Li D
  • Hyperthyroidism is characterized by an increase in the synthesis and secretion of thyroid hormones in the thyroid gland, and the most common cause of overproduction of thyroid hormones is Graves' disease (GD). Long-term disease models of hyperthyroidism have been established. In general, methods to induce GD include transfection of fibroblasts, injecting plasmids or adenovirus containing thyroid …
  • Gestational trimester-specific reference ranges for serum thyrotropin and free thyroxine in Japanese. [Journal Article]
    Endocr J. 2022 Jul 09 [Online ahead of print]Fuse Y, Ito Y, … Irie M
  • Thyroid diseases in pregnant and lactating women may result in adverse outcomes for both mothers and infants. A reference range for thyroid function is required in different areas; however, few studies on the gestational change or reference ranges of thyrotropin (TSH) and free thyroxine (FT4) concentrations for Japanese pregnant women have been reported. To establish the gestational trimester-spe…
  • Risk Factors from Pregnancy to Adulthood in Multiple Sclerosis Outcome. [Review]
    Int J Mol Sci. 2022 Jun 25; 23(13)González-Madrid E, Rangel-Ramírez MA, … Riedel CA
  • Multiple sclerosis (MS) is an autoimmune disease characterized by a robust inflammatory response against myelin sheath antigens, which causes astrocyte and microglial activation and demyelination of the central nervous system (CNS). Multiple genetic predispositions and environmental factors are known to influence the immune response in autoimmune diseases, such as MS, and in the experimental auto…
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