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Unbound Medicine.
(Pregnancy AND treatment of infertility)
28,606 results
  • Ethics and IVF add-ons: We need to talk about it. [Editorial]
    JBRA Assist Reprod. 2022 Aug 04; 26(3):371-373.Braga DPAF, Setti AS, Borges E
  • In vitro fertilization (IVF) 'add-ons' are adjunct treatments used in addition to standard IVF protocols, in an attempt to improve success rates. However, the benefits for add-ons are often not supported by high-quality evidence. Nevertheless, many infertile patients are willing to try anything that might help them to improve their chances of having a baby. Therefore, the use of add-ons has been …
  • Chromosomal polymorphisms in assisted reproduction: an analysis of 942 cycles. [Journal Article]
    Reprod Fertil. 2022 Jul 01; 3(3):133-139.Ralapanawe MSB, Gajaweera SL, … Gallos I
  • The use of intracytoplasmic sperm injection (ICSI) has recently increased worldwide. The live birth rate per ICSI cycle is low, and over half of infertile couples remain childless. Chromosomal polymorphisms are up to five times more common in couples with infertility compared to the general population. We aimed to investigate the association between chromosomal polymorphisms and reproductive outc…
  • Pregnancy in patients with systemic lupus erythematosus: a systematic review. [Review]
    Arch Gynecol Obstet. 2022 Aug 01 [Online ahead of print]Zhang S, Han X, … Wang J
  • Systemic lupus erythematosus (SLE)-a most common disorder in women of reproductive age-has been described to be associated with adverse pregnancy outcomes. Despite the increased health risks for the mother (preeclampsia, lupus flare, arterial hypertension, gestational diabetes mellitus and thrombotic risk when antiphospholipid antibodies are present) and fetus (miscarriage, stillbirth, premature …
  • Comparison of reproductive outcomes in subclinical hypothyroidism women with high-normal vs. low-normal thyroid-stimulation hormone levels after treatment with levothyroxine. [Journal Article]
    Clin Endocrinol (Oxf). 2022 Jul 28 [Online ahead of print]Zhang Y, Liu Y, … Guan Y
  • CONCLUSIONS: High-normal TSH levels did not have adverse effects on clinical and obstetric outcomes when compared with low-normal TSH levels after LT4 treatment. However, whether it is appropriate to set 2.5 mIU/L as the goal of treatment before IVF/ICSI remains to be determined in further well-designed studies.Few studies investigated whether strictly controlled TSH levels after LT4 treatment impair reproductive outcomes in infertile women with SCH. The aim of this study was to investigate the impact of high-normal vs. low-normal TSH levels on reproductive outcomes in women undergoing their first IVF-ET cycle. This was a retrospective cohort study. Patients were divided into low-normal (TSH <2.5 mIU/L, and ≥0.27 mIU/L) and high-normal (TSH≥2.5 mIU/L, and <4.2 mIU/L) groups based on TSH levels after LT4 treatment. We demonstrated that high-normal TSH levels did not have adverse effects on clinical and obstetric outcomes when compared with low-normal TSH levels after LT4 treatment. However, whether it is appropriate to set 2.5 mIU/L as the goal of treatment before IVF/ICSI remains to be determined in further well-designed studies. This article is protected by copyright. All rights reserved.
  • Obstetric outcomes of 297 women treated for vaginismus. [Journal Article]
    Eur J Obstet Gynecol Reprod Biol. 2022 Jul 23; 276:134-138.Zulfikaroglu E, Yaman S
  • CONCLUSIONS: Vaginismus patients should be treated prior to being deemed infertile, and other fertility treatments should be attempted. Moreover, the caesarean delivery rates of individuals with treated vaginismus are the same as those of the general population. Vaginal delivery after vaginismus treatment seems to be safe, with no increased perineal morbidity or vaginismus recurrence.
  • Gene mutations impede oocyte maturation, fertilization, and early embryonic development. [Journal Article]
    Bioessays. 2022 Jul 28 [Online ahead of print]Fei CF, Zhou LQ
  • Reproductive diseases are a long-standing problem and have become more common in the world. Currently, 15% of the world's population suffers from infertility, and half of them are women. Maturation of oocytes, successful fertilization, and high-quality embryos are prerequisites for pregnancy. With the development of assisted reproductive technology and advanced genetic assays, we have found that …
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