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(Pseudomonas)
112,999 results
  • The type IV pilus protein PilU functions as a PilT-dependent retraction ATPase. [Journal Article]
    PLoS Genet 2019; 15(9):e1008393Adams DW, Pereira JM, … Blokesch M
  • Type IV pili are dynamic cell surface appendages found throughout the bacteria. The ability of these structures to undergo repetitive cycles of extension and retraction underpins their crucial roles in adhesion, motility and natural competence for transformation. In the best-studied systems a dedicated retraction ATPase PilT powers pilus retraction. Curiously, a second presumed retraction ATPase …
  • A new ursane-type triterpene oxoglucopyranoside from Crossopteryx febrifuga. [Journal Article]
    Z Naturforsch C 2019Kayangar M, Ngansop Nono R, … Tapondjou LA
  • A new saponin, 3-O-β-d-3-oxo-glucopyranosyl-ursa-12,20(30)-diene-27,28-dioic acid (1), was isolated from the methanol extract of stem bark of Crossopteryx febrifuga together with the known 3β-d-glucopyranosyl-ursa-12,20(30)-diene-27,28-dioic acid (2), shanzhiside methyl ester (3), shanzhiside (4), β-sitosterol (5), β-sitosterol-3-O-β-d-glucopyranoside (6), ursa-12,20(30)-diene-27,28-dioic acid (7…
  • A Bacterial Effector Mimics a Host HSP90 Client to Undermine Immunity. [Journal Article]
    Cell 2019Lopez VA, Park BC, … Tagliabracci VS
  • The molecular chaperone HSP90 facilitates the folding of several client proteins, including innate immune receptors and protein kinases. HSP90 is an essential component of plant and animal immunity, yet pathogenic strategies that directly target the chaperone have not been described. Here, we identify the HopBF1 family of bacterial effectors as eukaryotic-specific HSP90 protein kinases. HopBF1 ad…
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