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108,927 results
  • Sleep Bruxism and Oral health-related Quality of life in Children: A Systematic Review. [Review]
    Int J Paediatr Dent 2019Rodrigues JA, Azevedo CB, … Lenzi TL
  • Sleep bruxism (SB) is a masticatory muscle activity during sleep that can cause several consequences to the stomatognathic system. This systematic review investigated the impact of SB on oral health-related quality of life (OHRQoL) of 0 to 6 years old children. Literature search was undertaken through PubMed/MEDLINE, LILACS, SCOPUS, TRIP, Livivo databases and grey literature. The search was condu…
  • A year in type 2 diabetes mellitus: 2018 review based on the Endorama lecture. [Review]
    Hormones (Athens) 2019Paschou SΑ, Alexandrides T
  • The aim of this article is to review and present the most important studies published in the field of type 2 diabetes mellitus (T2DM) during 2018. These studies were presented in a lecture given on this topic at the Endorama Meeting in Patras, Greece, in January 2019. In order to identify the most important and relevant articles, a search in the English language was conducted in PubMed for public…
  • Gluco-metabolic effects of pharmacotherapy-induced modulation of bile acid physiology. [Journal Article]
    J Clin Endocrinol Metab 2019Brønden A, Knop FK
  • CONCLUSIONS: Any potential beneficial gluco-metabolic effects of FXR-agonists remain to be established, whereas the clinical relevance of TGR5-based treatment modalities seems limited due to substantial safety concerns of TGR5 agonists observed in animal models. The glucose-lowering effects of ASBT inhibitors, bile acid sequestrants and metformin are at least partly mediated by modulation of bile acid circulation, which might allow an optimization of these bile acid modulating treatment modalities.
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