- Aerobic exercise inhibits obesity-induced respiratory phenotype. [Journal Article]
- CCytokine 2018 Feb 14; 104:46-52
- CONCLUSIONS: Aerobic exercise reduces high fat diet-induced obese lung phenotype (AHR, pulmonary remodeling and inflammation), involving anti-inflammatory cytokine IL-10 and adiponectin.
- Effect of multiple low-dose PGF2α injections on the mature corpus luteum in non-pregnant bitches. [Journal Article]
- TTheriogenology 2018 Feb 14; 113:34-43
- This study investigated molecular regulation in the canine corpus luteums/corpora lutea (CL) following multiple low-dose prostaglandin F2alpha (PGF2α) injections in non-pregnant bitches around 30-35 ...
This study investigated molecular regulation in the canine corpus luteums/corpora lutea (CL) following multiple low-dose prostaglandin F2alpha (PGF2α) injections in non-pregnant bitches around 30-35 days after ovulation. The CL were obtained by ovariohysterectomy 1 h after the last PGF2α injection. The subjects were divided into the following groups: control (no PGF2α injection, n = 4), one PGF2α injection (injection at 0 h, 1PGF, n = 4), two PGF2α injection (injection at 0 and 8 h, 2PGF, n = 4), and three PGF2α injection (injection at 0, 8 and 24 h, 3PGF, n = 4). In the 1PGF group, the steady-state mRNA levels of an immediate early gene (NR4A1) and immune system-related genes (MCP-1 and IL-8) increased. NR4A1 was localized in luteal and endothelial cells. In contrast, MCP-1 was localized in the luteal tissue between the luteal and endothelial cells. LHCGR, CYP11A1, and StAR mRNA expression decreased after the second PGF2α injection. FASLG increased only after the third PGF2α injection. The mRNA levels of PTGFR, PGT, and PTGS2 decreased as the number of PGF2α injections increased. Immunohistochemistry showed a decrease in StAR protein density as the number of PGF2α injections increased. BAX and CASP3 mRNA expression levels were similar among the groups. Serum progesterone (P4) levels decreased dramatically after the PGF2α injections but were still higher than the basal level at the end of the study. In conclusion, repeated low-dose PGF2α injections could induce luteolytic mechanisms in the CL of non-pregnant bitches. Furthermore, it can be concluded that, in non-pregnant bitches, some aspects of the molecular regulation of luteolysis in the CL are similar to some aspects of such regulation in other domestic animals.
- Apocynum venetum leaf extract reverses depressive-like behaviors in chronically stressed rats by inhibiting oxidative stress and apoptosis. [Journal Article]
- BPBiomed Pharmacother 2018 Feb 14; 100:394-406
- CONCLUSIONS: Our findings suggested that AVLE exerted antidepressant-like effects in CUMS rats, which was possibly mediated by the prevention of oxidative stress, the inhibition of hippocampal neuronal apoptosis, and the upregulation of the hippocampal BDNF level.
- Biological effects of four iron-containing nanoremediation materials on the green alga Chlamydomonas sp. [Journal Article]
- EEEcotoxicol Environ Saf 2018 Feb 14; 154:36-44
- As nanoremediation strategies for in-situ groundwater treatment extend beyond nanoiron-based applications to adsorption and oxidation, ecotoxicological evaluations of newly developed materials are re...
As nanoremediation strategies for in-situ groundwater treatment extend beyond nanoiron-based applications to adsorption and oxidation, ecotoxicological evaluations of newly developed materials are required. The biological effects of four new materials with different iron (Fe) speciations ([i] FerMEG12 - pristine flake-like milled Fe(0) nanoparticles (nZVI), [ii] Carbo-Iron®- Fe(0)-nanoclusters containing activated carbon (AC) composite, [iii] Trap-Ox® Fe-BEA35 (Fe-zeolite) - Fe-doped zeolite, and [iv] Nano-Goethite - 'pure' FeOOH) were studied using the unicellular green alga Chlamydomonas sp. as a model test system. Algal growth rate, chlorophyll fluorescence, efficiency of photosystem II, membrane integrity and reactive oxygen species (ROS) generation were assessed following exposure to 10, 50 and 500 mg L-1of the particles for 2 h and 24 h. The particles had a concentration-, material- and time-dependent effect on Chlamydomonas sp., with increased algal growth rate after 24 h. Conversely, significant intracellular ROS levels were detected after 2 h, with much lower levels after 24 h. All Fe-nanomaterials displayed similar Z-average sizes and zeta-potentials at 2 h and 24 h. Effects on Chlamydomonas sp. decreased in the order FerMEG12 > Carbo-Iron® > Fe-zeolite > Nano-Goethite. Ecotoxicological studies were challenged due to some particle properties, i.e. dark colour, effect of constituents and a tendency to agglomerate, especially at high concentrations. All particles exhibited potential to induce significant toxicity at high concentrations (500 mg L-1), though such concentrations would rapidly decrease to mg or µg L-1in aquatic environments, levels harmless to Chlamydomonas sp. The presented findings contribute to the practical usage of particle-based nanoremediation in environmental restoration.
- Diarylheptanoid from rhizomes of Curcuma kwangsiensis (DCK) inhibited imiquimod-induced dendritic cells activation and Th1/Th17 differentiation. [Journal Article]
- IIInt Immunopharmacol 2018 Feb 14; 56:339-348
- CONCLUSIONS: These data together demonstrate a potential role of DCK in suppressing the biological function of DCs, and provide a possible mechanism for understanding the effects of herb Curcuma kwangsiensis in treating psoriasis.
- Combined effect of water inundation and heavy metals on the photosynthesis and physiology of Spartina alterniflora. [Journal Article]
- EEEcotoxicol Environ Saf 2018 Feb 14; 153:248-258
- The frequency and duration of tidal flooding significantly influence the bioavailability of heavy metals (HMs) in sediment and hence exert toxicological effects on coastal wetland plants. In this stu...
The frequency and duration of tidal flooding significantly influence the bioavailability of heavy metals (HMs) in sediment and hence exert toxicological effects on coastal wetland plants. In this study, the combined effects of different water inundation times (3, 6, 9, and 12 h) and HMs (Cu, Zn, Pb, and Cr) on the photosynthesis and physiology of Spartina alterniflora were investigated under greenhouse conditions. Results showed that S. alterniflora was somehow tolerant to the combined HMs treatments, and only the highest level of HM treatment decreased leaf chlorophyll content. Furthermore, the plants did not show any signs of victimization. Different times of water inundation with HMs did not exert any significant effect on the malonaldehyde (MDA) and chlorophyll contents in the leaves of S. alterniflora at day 20. Prolonged water inundation time at day 60 significantly reduced leaf chlorophyll content with the decrease in leaf photosynthetic rate, which was accompanied by a significant increase in the intercellular concentration of CO2. At day 60, abscisic acid dose-dependently increased along the different water inundation times, indicating that this phytohormone is involved in plant responses to flooding stress. Peroxidase (POD), superoxide dismutase (SOD), and ascorbate peroxidase (APX), showed different responses to the combined treatment of water inundation and HMs at different times. At day 20, the long duration of water inundation and HMs treatments (9 h+HMs and/or 12 h+HMs) significantly increased enzyme activity in the leaves compared with the control group (6 h). At day 60, the POD and SOD activities in the leaves of S. alterniflora decreased with prolonged water inundation time, and root APX activity significantly decreased compared with the 6 h water inundation treatment.
- Barrier effects of remote high mountain on atmospheric metal transport in the eastern Tibetan Plateau. [Journal Article]
- STSci Total Environ 2018 Feb 14; 628-629:687-696
- Anthropogenic metals adsorbed on suspended fine particles can be deposited on remote and inaccessible high mountains by long-range atmospheric transport. In this study, we investigated the cadmium (C...
Anthropogenic metals adsorbed on suspended fine particles can be deposited on remote and inaccessible high mountains by long-range atmospheric transport. In this study, we investigated the cadmium (Cd) and lead (Pb) in the soils, mosses and rainfall of three transects on the Gongga Mountain, eastern Tibetan Plateau, to understand the mountain interception effects on their atmospheric transport. The concentrations of Cd and Pb in the soils and mosses displayed a pattern of eastern transect>northern transect>western transect. The distribution of Cd and Pb on the eastern transect increased from 2000 to 2900m a.s.l. (above sea level), decreased toward the timberline, and increased again with altitude; on the northern transect, it generally decreased with altitude whereas a distribution trend was not clearly observed on the western transect. The Cd and Pb concentrations in the rainfall of the eastern transect generally decreased with altitude, and they were higher inside forests than outside forests and temporally higher in the winter than the summer. The Pb isotopic ratios coupled with moss bio-monitoring distinguished anthropogenic sources of Cd and Pb on the eastern and northern transects, whereas bedrock weathering was the main source of Cd and Pb on the western transect. We proposed a conceptual model to delineate the effects of terrain, local climate and vegetation on the transport of atmospheric metals. Our results highlighted the high mountains in the eastern Tibetan Plateau as an effective natural barrier limiting atmospheric metal transport.
- Repeated treatments of ciprofloxacin and kresoxim-methyl alter their dissipation rates, biological function and increase antibiotic resistance in manured soil. [Journal Article]
- STSci Total Environ 2018 Feb 14; 628-629:661-671
- The dissipation of ciprofloxacin (CIP, 1.0 and 10.0mg/kg) and kresoxim-methyl (KM, 1.0 and 2.0mg/kg) in manure-amended soil, the variations in soil enzyme activities and microbial functional diversit...
The dissipation of ciprofloxacin (CIP, 1.0 and 10.0mg/kg) and kresoxim-methyl (KM, 1.0 and 2.0mg/kg) in manure-amended soil, the variations in soil enzyme activities and microbial functional diversities, and CIP-induced bacterial community tolerances were studied using a chromatographic analysis, enzyme colorimetric and titration analyses, and the BIOLOG EcoPlate method. Three successive treatments of individual and combined samples of CIP and KM at low and high concentrations were performed at 60d intervals. The dissipation half-life of CIP increased, but that of KM decreased in manured soil with treatment frequency; furthermore, the combined treatment altered the dissipation rates of CIP and KM. A stronger inhibitory effect on the activities of soil neutral phosphatase and urease was observed in the individual KM treatment than in the individual CIP treatment. A similar inhibitory trend was also found in soil neutral phosphatase activity in the combined treatment at high concentration compared to that at low concentration, but the activity of soil catalase was enhanced in the early stages of the KM or CIP treatments. Meanwhile, the inhibitory trend on the overall activity and functional diversity of soil microorganisms was observed in the individual KM or CIP treatment, and the combined treatment exerted a greater suppression effect than that in the individual treatment. Bacterial community resistance to CIP increased significantly with increasing treatment frequency and concentration, and furthermore antibiotic resistance developed faster in the combined treatment than in the individual treatment. It was concluded that the repeated treatments of CIP and KM could alter their dissipation rates and soil enzyme activities, suppress microbial functional diversity, and increase bacterial community resistance to CIP in manured soil.
- Effect of clonal integration on nitrogen cycling in rhizosphere of rhizomatous clonal plant, Phyllostachys bissetii, under heterogeneous light. [Journal Article]
- STSci Total Environ 2018 Feb 14; 628-629:594-602
- Clonal integration plays an important role in clonal plant adapting to heterogeneous habitats. It was postulated that clonal integration could exhibit positive effects on nitrogen cycling in the rhiz...
Clonal integration plays an important role in clonal plant adapting to heterogeneous habitats. It was postulated that clonal integration could exhibit positive effects on nitrogen cycling in the rhizosphere of clonal plant subjected to heterogeneous light conditions. An in-situ experiment was conducted using clonal fragments of Phyllostachys bissetii with two successive ramets. Shading treatments were applied to offspring or mother ramets, respectively, whereas counterparts were treated to full sunlight. Rhizomes between two successive ramets were either severed or connected. Extracellular enzyme activities and nitrogen turnover were measured, as well as soil properties. Abundance of functional genes (archaeal or bacterial amoA, nifH) in the rhizosphere of shaded, offspring or mother ramets were determined using quantitative polymerase chain reaction. Carbon or nitrogen availabilities were significantly influenced by clonal integration in the rhizosphere of shaded ramets. Clonal integration significantly increased extracellular enzyme activities and abundance of functional genes in the rhizosphere of shaded ramets. When rhizomes were connected, higher nitrogen turnover (nitrogen mineralization or nitrification rates) was exhibited in the rhizosphere of shaded offspring ramets. However, nitrogen turnover was significantly decreased by clonal integration in the rhizosphere of shaded mother ramets. Path analysis indicated that nitrogen turnover in the rhizosphere of shaded, offspring or mother ramets were primarily driven by the response of soil microorganisms to dissolved organic carbon or nitrogen. This unique in-situ experiment provided insights into the mechanism of nutrient recycling mediated by clonal integration. It was suggested that effects of clonal integration on the rhizosphere microbial processes were dependent on direction of photosynthates transport in clonal plant subjected to heterogeneous light conditions.
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- Farmyard manure alone and combined with immobilizing amendments reduced cadmium accumulation in wheat and rice grains grown in field irrigated with raw effluents. [Journal Article]
- CChemosphere 2018 Feb 08; 199:468-476
- Cadmium (Cd) stress is a serious concern in agricultural soils worldwide whereas little is known about the impact of farmyard manure (FYM) alone or combined with limestone, lignite and biochar on Cd ...
Cadmium (Cd) stress is a serious concern in agricultural soils worldwide whereas little is known about the impact of farmyard manure (FYM) alone or combined with limestone, lignite and biochar on Cd concentrations in plants. Wheat was grown in Cd-contaminated field amended with control (T1), FYM @ 0.1% (T2), FYM + limestone @ 0.05% each (T3), FYM + lignite @ 0.05% each (T4), FYM + biochar @ 0.05% each (T5) and subsequent rice was grown without additional use of amendments. Soil application of amendments increased straw and grain yield and thousand grain weight being maximum in FYM + limestone treatment. Wheat and rice straw yield increased by 19% and 10% in T3than control respectively. Photosynthetic pigments increased with the supply of amendments than control. Amendments decreased Cd concentration, total Cd uptake in straw and grains and Cd harvest index of both crops and the maximum reduction in these parameters was recorded with where FYM + limestone (T3). Cd concentration in wheat and rice straw decreased by 78.5% and 65% in T3than control, respectively. The highest benefit to cost ratio was obtained in FYM + limestone (T3). Ammonium bicarbonate - diethylenetriamine penta acetic acid (AB-DTPA) extractable Cd of the post-harvest soil reduced whereas Cd immobilization index and soil pH increased with the supply of all treatments than control being maximum in T3.The present study revealed that field management with FYM + limestone increased plant yield and reduced Cd concentrations in grains.