- Refractory pyoderma gangrenosum in a patient with Crohn´s Disease: complete response to Ustekinumab. [Journal Article]
- JCJ Crohns Colitis 2018 Dec 07
- Abdominal ultrasound in paraneoplastic Pyoderma gangrenosum caused by renal carcinoma. [Letter]
- MUMed Ultrason 2018 Dec 08; 20(4):541-542
- We present the case of a 60-year-old male patient, with refractory ulcers in the groin. Ultrasoundand CT showed a large vascularized tumor of the kidney with cystic parts and inhomogeneous dynamic be...
We present the case of a 60-year-old male patient, with refractory ulcers in the groin. Ultrasoundand CT showed a large vascularized tumor of the kidney with cystic parts and inhomogeneous dynamic behaviour. Histology demonstrated Pyoderma gangrenosum (ulcer) and well differentiated adenocarcinoma (kidney). Pyoderma gangrenosum appears as paraneoplastic manifestation in about 7% of cases, especially in lymphomas and tumors involving the digestive tract.Particularities of the case consisted in the accidental discovery of the renal tumor, in spite of the lack of urinary syndromes. The present case highlights the importance of tumor screening in patients with atypical antibiotic-refractory skin ulcers.
- Pyoderma gangrenosum around an ileostoma: A case report. [Journal Article]
- MMedicine (Baltimore) 2018; 97(48):e13415
- CONCLUSIONS: Medical staff should not neglect peristoaml dermatitis because of its common occurrence. Once the situation develops beyond the doctors' expectation, more efforts should be made to treat it, even expand debridement if possible.
- Bilateral pyoderma gangrenosum associated with ulcerative colitis and restorative proctocolectomy. [Journal Article]
- GHGastroenterol Hepatol 2018 Nov 20
- Hepatobiliary and Pancreatic: Pyoderma gangrenosum of the pancreas successfully treated with infliximab. [Journal Article]
- JGJ Gastroenterol Hepatol 2018 Nov 22
- Utility of Skin Biopsy and Culture in the Diagnosis and Classification of Chronic Ulcers: A Single-Institution, Retrospective Study. [Journal Article]
- AJAm J Dermatopathol 2018 Nov 15
- In the United States, chronic ulcers affect 6.5 million people, with a cost of ≈$20 million annually. The most common etiology of chronic ulcers in the United States is venous stasis, followed by art...
In the United States, chronic ulcers affect 6.5 million people, with a cost of ≈$20 million annually. The most common etiology of chronic ulcers in the United States is venous stasis, followed by arterial insufficiency and neuropathic ulcers. Less common causes of chronic ulcers include infection, inflammatory etiologies such as vasculitis and pyoderma gangrenosum, and neoplastic causes. Obtaining skin biopsy and tissue culture can be helpful in diagnosing unusual causes of chronic ulcers; however, there are little data on the diagnostic utility of skin biopsy in rendering a definitive diagnosis of the etiology of chronic ulcers. A retrospective study of all skin ulcers biopsied during a 10-year period at the University of Washington was undertaken. Re-excisions and surgical wounds were excluded. A total of 270 ulcer biopsy specimens were included. In 48% of cases, no specific diagnosis could be rendered histologically. 44.8% of chronic ulcers biopsied were due to atypical causes, with neoplasms (basal cell carcinoma, squamous cell carcinoma, melanoma, and cutaneous T-cell lymphoma) being the most common. Vasculitis and pyoderma gangrenosum each represented 1.5% of rendered diagnoses. Concomitant skin culture was performed in 28.9% of cases, and special stains [acid-fast bacilli, Brown and Brenn (B&B), Grocott's methenamine silver, and periodic acid-Schiff stains] were performed in 34.0%. Although more than half (49 of 78) of tissue cultures were positive, only 6.8% (12 of 175) of special stains on tissue sections were positive. We conclude that although the etiology of many ulcers cannot be determined by routine histology alone, skin biopsy of ulcers remains a critical part of the workup given that when a specific cause can be determined, atypical etiologies, including neoplasms, represent a significant proportion of chronic ulcers. Limitations of our study include referral bias. Our results also confirm the higher diagnostic yield of conventional tissue culture compared with special tissue stain biopsies of skin ulcers.
- Association of pyoderma gangrenosum, erythema nodosum and aseptic liver abscess without significant underlying disease. [Letter]
- CEClin Exp Dermatol 2018 Nov 20
- Diagnostic pitfalls in the differentiation between pyoderma gangrenosum and necrotizing fasciitis. [Journal Article]
- AOActa Orthop Belg 2018; 84(1):17-24
- Pyoderma gangrenosum and necrotizing fasciitis are two rare pathologic entities with a similar clinical image, but a who require a very different management. In general physicians, orthopedics, derma...
Pyoderma gangrenosum and necrotizing fasciitis are two rare pathologic entities with a similar clinical image, but a who require a very different management. In general physicians, orthopedics, dermatologists, plastic surgeons will hardly ever see it, but when they do it is very important to distinguish between both. In this paper with the focus on the practical approach ,we expose the diagnostic pitfalls in the differential diagnosis, explain how to prevent them and summarize the evidence on therapeutic management. To achieve this we use a case where the diagnosis was rather difficult and utilize reviews where the clinical features, early diagnostic tools and treatment options are explained.
- Two cases of maggot debridement therapy in pyoderma gangrenosum. [Journal Article]
- JCJAAD Case Rep 2018; 4(10):1027-1029
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- Wound Healing Disorder Caused by Pyoderma Gangrenosum. [Journal Article]
- ASAm Surg 2018 Mar 01; 84(3):e112-e113