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(Renal failure acute)
74,011 results
  • Analytical performance of an immunoassay to measure proenkephalin. [Journal Article]
  • CBClin Biochem 2018 May 18
  • Donato LJ, Meeusen JW, … Jaffe AS
  • CONCLUSIONS: Both assay formats are accurate and precise for measuring clinically relevant PENK concentrations. The association of PENK concentration with mGFR is influenced by gender, age, and history of kidney transplantation. Future studies will determine if blood PENK can be used clinically to estimate GFR and/or detect AKI.
  • [NGAL as a marker for some extrarenal complications in acute coronary syndrome]. [Journal Article]
  • KKardiologiia 2018 SMar; (S3):19-26
  • Shalenkova MA, Mikhailova ZD, Klimkin PF
  • CONCLUSIONS: Urinary levels of NGAL were significantly higher in ACS patients with than without AHF or signs of pulmonary hypertension. NGAL values >9.96 ng/ml were associated with an increased probability of AHF during stay in the hospital, and NGAL values >5.81 ng/ml - with a higher incidence of ACS patients with signs of pulmonary hypertension. In ACS, direct correlations of blood and urinary levels of NGAL with some echocardiographic parameters reflecting the systolic function and the LV dimensions and geometry were identified. Levels of u-NGAL were found to be positively correlated with blood levels NT-proBNP. NGAL may be used as a supplementary marker not only for acute kidney injury and chronic kidney disease but also for severity of cardiovascular conditions and heart remodeling in patients after exacerbation of ischemic heart disease.
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