- Non-GVHD ocular complications after hematopoietic cell transplantation: expert review from the Late Effects and Quality of Life Working Committee of the CIBMTR and Transplant Complications Working Party of the EBMT. [Review]
- BBBiol Blood Marrow Transplant 2018 Dec 03
- Non-graft-versus-host disease (non-GVHD) ocular complications are generally uncommon after hematopoietic cell transplantation (HCT), but can cause prolonged morbidity affecting activities of daily li...
Non-graft-versus-host disease (non-GVHD) ocular complications are generally uncommon after hematopoietic cell transplantation (HCT), but can cause prolonged morbidity affecting activities of daily living and quality of life. Here we provide an expert review of non-GVHD ocular complications in a collaboration between transplant physicians and ophthalmologists through the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and the Transplant Complications Working Party of the European Society of Blood and Marrow Transplantation. Complications discussed in this review include cataracts, glaucoma, ocular infections, ocular involvement with malignancy, ischemic microvascular retinopathy, central retinal vein occlusion, retinal hemorrhage, retinal detachment and ocular toxicities associated with medications. We have summarized incidence, risk factors, screening, prevention and treatment of individual complications and generated evidence-based recommendations. Baseline ocular evaluation before HCT should be considered in all patients who undergo HCT. Follow-up evaluations should be considered according to clinical symptoms, signs and risk factors. Better preventive strategies and treatments remain to be investigated for individual ocular complications after HCT. Both transplant physicians and ophthalmologists should be knowledgeable of non-GVHD ocular complications and provide comprehensive collaborative team care.
- Hypertensive crisis with massive retinal and choroidal infarction: A case update. [Journal Article]
- AJAm J Ophthalmol Case Rep 2019; 13:22-24
- CONCLUSIONS: There is a strong association between severity of retinopathy and level of kidney function. Although a rare presentation, hypertensive retinopathy is a common complication of end-stage renal disease and can be a devastating process as emphasized by this report. Those with auto-immune renal disease, such as IgA nephropathy, are at higher risk for retino-choroidal complications. It should remind all ophthalmologists and clinicians on the necessity of closer eye examinations for these patients, particularly for those with auto-immune renal disease.
- Functional Connectivity of Paired Default Mode Network Subregions in Retinal Detachment. [Journal Article]
- TVTransl Vis Sci Technol 2018; 7(6):15
- CONCLUSIONS: The visual function impairments of RD patients were closely related to the DMN functional connections, which provided insight into the neural variation in RD patients and assisted in revealing the potential mechanisms of RD.
- Rétinopathie diabétique. [Journal Article]
- RPRev Prat 2016; 67(9):1001-1008
- Diabetic retinopathy. Diabetic retinopathy (DR) is a disease whose screening actually can change the functional prognosis for the patients. It makes blindness avoidable. Annual screening using fundus...
Diabetic retinopathy. Diabetic retinopathy (DR) is a disease whose screening actually can change the functional prognosis for the patients. It makes blindness avoidable. Annual screening using funduscopy or retinography for all diabetic patients is mandatory and yet not sufficiently and systematically performed in France. French Public health authority is developping telemedicine screening programs in different french regions to improve the prevention of DR. The treatment of DR is based on the management of its 2 major complications, that can coexist: preretinal neovascular proliferation (proliferative diabetic retinopathy), and diabetic macular edema (DME). Both of these complications require preventive management through strict control of blood glucose, blood pressure and hyperlipidemia. Once the complication is present, PRP must be performed to treat the neovessels while antiVEGF or corticosteroids intravitreal injections are the best way to treat DME. Surgery is required for more complicated forms of DR, such as intra-vitreous haemorrhage, retinal detachment, or neovascular glaucoma.
- Micropulse Laser for Persistent Sub-Retinal Fluid in a Patient Previously Treated for Rhegmatogenous Retinal Detachment. [Journal Article]
- MHMed Hypothesis Discov Innov Ophthalmol 2018; 7(4):190-194
- The purpose of this study was to report the resolution of persistent Sub-Retinal Fluid (SRF) induced by subthreshold micropulse laser treatment in a patient, formerly treated for rhegmatogenous retin...
The purpose of this study was to report the resolution of persistent Sub-Retinal Fluid (SRF) induced by subthreshold micropulse laser treatment in a patient, formerly treated for rhegmatogenous retinal detachment by retinal pneumopexy. The case was a 41-year-old male, who initially presented macula-splitting rhegmatogenous retinal detachment and corrected distance visual acuity of 20/40 in his left eye. He was treated by retinal pneumopexy and laser retinopexy. Retina was flattened and vision improved to 20/30. However, the subretinal fluid (SRF) under the fovea was persistently observed on repeated retinal exams. Fourteen months after the initial pneumopexy, subthreshold micropulse laser was applied to cover the entire area of the SRF. The improvement started two weeks afterwards and the SRF completely resolved within four months after the application of micropulse laser. Corrected distance visual acuity improved from 20/30 to 20/20, accompanied by marked improvement in patient's complaints on visual blurriness. The patient was followed up for three years and no recurrence of SRF was noted. The findings of this report indicate that subthreshold micropulse laser may serve as a therapeutic option for persistent SRF, which may be observed after successful retinal detachment repair.
- Bilateral identical intervals between phacoemulsification procedures performed 23 years before retinal detachment. [Journal Article]
- OJOman J Ophthalmol 2018 Sep-Dec; 11(3):274-276
- We aim to present a case of bilateral rhegmatogenous retinal detachment (RRD) after successful phacoemulsification procedures performed 23 years before RRD onset and surgical management. A 57-year-ol...
We aim to present a case of bilateral rhegmatogenous retinal detachment (RRD) after successful phacoemulsification procedures performed 23 years before RRD onset and surgical management. A 57-year-old female presented with blurred vision due to floaters in the left eye. The patient was followed up with dilated fundus examination. The patient underwent bilateral uneventful cataract extraction 23 years before the baseline visit with the use of phacoemulsification. Dilated fundus examination revealed RRD in the left eye that was managed with a 25G pars plana vitrectomy, cryopexy, and 16% C3F8 expandable gas. Thirty-three days following the procedure in the left eye, the patient presented with RRD in the right eye. Management included a 25G pars plana vitrectomy with cryopexy and 20% SF6 expandable gas. Phacoemulsification ultrasound energy appears to bring about changes in the peripheral vitreous and retina that may manifest several decades following uncomplicated cataract extraction.
- Large drusen in long-standing retinal detachment. [Journal Article]
- OJOman J Ophthalmol 2018 Sep-Dec; 11(3):272-273
- Drusen are seen as an end result of various biochemical insults to the retina and have been described in various clinical settings. We would like to report the histopathology of a case of large druse...
Drusen are seen as an end result of various biochemical insults to the retina and have been described in various clinical settings. We would like to report the histopathology of a case of large drusen, seen associated with chronic retinal detachment in a case of childhood trauma, where the eye was eviscerated for other reasons.
- Reductions in final visual acuity occur even within the first 3 days after a macula-off retinal detachment. [Journal Article]
- BJBr J Ophthalmol 2018 Dec 01
- CONCLUSIONS: DMD affects the final VA even among patients whose DMD is <3 days. Based on these results, interventions that shorten DMD, including those occurring within the first 3days, may result in improved long-term VA outcomes.
- Retinal Nerve Fiber Layer Thickness Changes after Phacoemulsification with Intraocular Lens Implantation. [Journal Article]
- JCJ Coll Physicians Surg Pak 2018; 28(12):919-922
- CONCLUSIONS: Removal of cataract by surgery enhances the OCT measurement of retinal nerve fiber layer, resulting in increased thickness.
New Search Next
- Intravitreal ranibizumab versus laser photocoagulation for retinopathy of prematurity: efficacy, anatomical outcomes and safety. [Journal Article]
- BJBr J Ophthalmol 2018 Dec 04
- CONCLUSIONS: Intravitreal ranibizumab for ROP appears to achieve similar therapeutic effects than did laser photocoagulation, but with fewer surgical complications such as retinal detachment or macular dragging.