Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.
(RotaTeq)
462 results
  • The Impact of Human Genetic Polymorphisms on Rotavirus Susceptibility, Epidemiology, and Vaccine Take. [Review]
    Viruses. 2020 Mar 17; 12(3)Sharma S, Hagbom M, … Nordgren J
  • Innate resistance to viral infections can be attributed to mutations in genes involved in the immune response, or to the receptor/ligand. A remarkable example of the latter is the recently described Mendelian trait resistance to clinically important and globally predominating genotypes of rotavirus, the most common agent of severe dehydrating gastroenteritis in children worldwide. This resistance…
  • Genetic Diversity of Human Rotavirus A Among Hospitalized Children Under-5 Years in Lebanon. [Journal Article]
    Front Immunol. 2020; 11:317.Harastani HH, Reslan L, … Zaraket H
  • Human rotavirus remains a major cause of gastroenteritis worldwide despite the availability of effective vaccines. In this study, we investigated the genetic diversity of rotaviruses circulating in Lebanon. We genetically characterized the VP4 and VP7 genes encoding the outer capsid proteins of 132 rotavirus-associated gastroenteritis specimens, previously identified in hospitalized children (<5 …
  • Rotavirus vaccines in clinical development: Current pipeline and state-of-the-art. [Journal Article]
    Pediatr Allergy Immunol. 2020 02; 31 Suppl 24:58-60.Sartorio MUA, Folgori L, … Mameli C
  • Rotavirus (RV) disease is a leading cause of mortality and morbidity, especially in children under 5 years of age. The introduction of the two oral rotavirus vaccines Rotarix® and RotaTeq® has shown significant reductions in RV-related mortality, severe RV disease, and hospitalizations. However, some barriers, including a reduced efficacy in low-income countries, safety issues regarding the intus…
  • [Rotavirus genomics. Public health impact]. [Review]
    Salud Publica Mex. 2020 Jan-Feb; 62(1):36-41.López S, Arias CF
  • With the introduction of rotavirus vaccines Rotarix (RV1) or RotaTeq (RV5) in the immunization programs of an increasing number of countries, there is concern that the immune selection pressure induced will cause an increase in the prevalence of virus genotypes not included in the vaccine formulation, or to the appearance of novel rotavirus strains that could evade the protective immune response.…
  • Vaccines for preventing rotavirus diarrhoea: vaccines in use. [Meta-Analysis]
    Cochrane Database Syst Rev. 2019 10 28; 2019(10)Soares-Weiser K, Bergman H, … Cunliffe N
  • CONCLUSIONS: RV1, RV5, and Rotavac prevent episodes of rotavirus diarrhoea. Whilst the relative effect estimate is smaller in high-mortality than in low-mortality countries, there is a greater number of episodes prevented in these settings as the baseline risk is much higher. We found no increased risk of serious adverse events. 21 October 2019 Up to date All studies incorporated from most recent search All published trials found in the last search (4 Apr, 2018) were included and 15 ongoing studies are currently awaiting completion (see 'Characteristics of ongoing studies').
  • Structural Basis of Glycan Recognition in Globally Predominant Human P[8] Rotavirus. [Journal Article]
    Virol Sin. 2019 Oct 16 [Online ahead of print]Sun X, Dang L, … Duan Z
  • Rotavirus (RV) causes acute gastroenteritis in infants and children worldwide. Recent studies showed that glycans such as histo-blood group antigens (HBGAs) function as cell attachment factors affecting RV host susceptibility and prevalence. P[8] is the predominant RV genotype in humans, but the structural basis of how P[8] RVs interact with glycan ligands remains elusive. In this study, we chara…
  • Histo-blood group antigens and rotavirus vaccine shedding in Nicaraguan infants. [Journal Article]
    Sci Rep. 2019 Jul 24; 9(1):10764.Bucardo F, Reyes Y, … Nordgren J
  • ABO, Lewis and secretor histo-blood group antigens (HBGA) are susceptibility factors for rotavirus in a P-genotype dependent manner and can influence IgA seroconversion rates following rotavirus vaccination. To investigate the association between HBGA phenotypes and rotavirus vaccine shedding fecal samples (n = 304) from a total of 141 infants vaccinated with Rotarix (n = 71) and RotaTeq (n = 70)…
  • Australian Rotavirus Surveillance Program: Annual Report, 2017 [Journal Article]
    Commun Dis Intell (2018). 2019 Jul 16; 43Roczo-Farkas S, Cowley D, … the Australian Rotavirus Surveillance Group
  • This report, from the Australian Rotavirus Surveillance Program and collaborating laboratories Australia-wide, describes the rotavirus genotypes identified in children and adults with acute gastroenteritis during the period 1 January to 31 December 2017. During this period, 2,285 faecal specimens were referred for rotavirus G and P genotype analysis, including 1,103 samples that were confirmed as…
  • Human rotavirus in Iran; molecular epidemiology, genetic diversity and recent updates on vaccine advances. [Review]
    Gastroenterol Hepatol Bed Bench. 2019 Spring; 12(2):98-109.Tavakoli Nick S, Mohebbi SR, … Hosseini SM
  • Human rotavirus is the predominant pathogen causing gastroenteritis in infants and children younger than 5 years of age globally. Before introduction and implementation of rotavirus vaccine, more than frothy percent of all caused acute gastroenteritis hospitalization and nearly half a million deaths per year was occurred due to Rotavirus infection mostly in the low-income countries. Rotaviruses a…
  • Prevalence and Genotypic Distribution of Rotavirus in Thailand: A Multicenter Study. [Multicenter Study]
    Am J Trop Med Hyg. 2019 05; 100(5):1258-1265.Sakpaisal P, Silapong S, … Mason CJ
  • Rotavirus has been one of the major etiological agents causing severe diarrhea in infants and young children worldwide. In Thailand, rotavirus contributes to one-third of reported pediatric diarrheal cases. We studied stool samples from 1,709 children with acute gastroenteritis and 1,761 children with no reported gastroenteritis whose age ranged from 3 months to 5 years from four different region…
  • Vaccines for preventing rotavirus diarrhoea: vaccines in use. [Meta-Analysis]
    Cochrane Database Syst Rev. 2019 03 25; 3:CD008521.Soares-Weiser K, Bergman H, … Cunliffe N
  • CONCLUSIONS: RV1, RV5, and Rotavac prevent episodes of rotavirus diarrhoea. Whilst the relative effect estimate is smaller in high-mortality than in low-mortality countries, there is a greater number of episodes prevented in these settings as the baseline risk is much higher. We found no increased risk of serious adverse events.
New Search Next