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8,331 results
  • Aminoacyl-tRNA synthetase deficiencies in search of common themes. [Journal Article]
  • GMGenet Med 2018 Jun 06
  • Fuchs SA, Schene IF, … van Hasselt PM
  • CONCLUSIONS: We propose a common clinical phenotype for recessive ARS deficiencies, resulting from insufficient aminoacylation activity to meet translational demand in specific organs or periods of life. Assuming residual ARS activity, adequate protein/amino acid supply seems essential instead of the traditional replacement of protein by glucose in patients with metabolic diseases.
  • Making head or tail of cnidarian hox gene function. [Journal Article]
  • NCNat Commun 2018 Jun 05; 9(1):2187
  • Rentzsch F, Holstein TW
  • Distantly related animals have spectacularly different shapes and body plans, which can render it difficult to understand which of their body parts may have a shared evolutionary origin. Studying the...
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