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2,216 results
  • Fast and slow biomembrane solubilizing detergents: Insights into their mechanism of action. [Journal Article]
    Colloids Surf B Biointerfaces 2019; 183:110430Lete MG, Monasterio BG, … Goñi FM
  • Detergents are water-soluble amphiphiles. Above a critical concentration they self-organize in micelles and in the presence of phospholipids mixed micelles are formed. Much information is available on the structure of these self-assemblies and on the thermodynamics of their formation. The aim of this study was to deepen our understanding of the mechanisms of solubilization. Solubilization of lipi…
  • Robust continuous in vitro culture of the Plasmodium cynomolgi erythrocytic stages. [Journal Article]
    Nat Commun 2019; 10(1):3635Chua ACY, Ong JJY, … Bifani P
  • The ability to culture pathogenic organisms substantially enhances the quest for fundamental knowledge and the development of vaccines and drugs. Thus, the elaboration of a protocol for the in vitro cultivation of the erythrocytic stages of Plasmodium falciparum revolutionized research on this important parasite. However, for P. vivax, the most widely distributed and difficult to treat malaria pa…
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