- Prevalence of pain due to rhinosinusitis: a review. [Journal Article]
- NSNeurol Sci 2018; 39(Suppl 1):21-24
- Headache secondary to sinonasal disease is still overestimated in the diagnostic pathway of cephalalgia. Contrary to belief, so-called sinus headaches are fairly uncommon and seen mostly in acute sin...
Headache secondary to sinonasal disease is still overestimated in the diagnostic pathway of cephalalgia. Contrary to belief, so-called sinus headaches are fairly uncommon and seen mostly in acute sinusitis or acute exacerbations. Even though literature has written extensively about the prevalence of migraines in self-diagnosed or primary care-diagnosed sinus headache, there is only a small body of literature regarding the real prevalence of pain and headache occurring during acute and chronic sinusitis.We reviewed the current literature and clarified the differences in presentation of pain for acute and chronic sinusitis, highlighting the higher prevalence of pain in chronic rhinosinusitis without polyps versus with polyps. Furthermore, we stressed the need for a rethinking in the clinical diagnosis of sinusitis based on pain as a major symptom.
- Endocannabinoid receptor CB2R is significantly expressed in aspirin-exacerbated respiratory disease: a pilot study. [Journal Article]
- IFInt Forum Allergy Rhinol 2018 Jun 13
- CONCLUSIONS: The endocannabinoid system is an emerging immunomodulatory network that may be involved in AERD. This is the first study of CB2R in sinonasal disease, showing significantly increased transcription in nasal polyps from subjects with AERD. Additional study is warranted to further evaluate the contribution and therapeutic potential of this novel finding in chronic rhinosinusitis.
- Size of septectomy does not affect distribution of nasal irrigation after endoscopic modified Lothrop procedure. [Journal Article]
- IFInt Forum Allergy Rhinol 2018 Jun 08
- CONCLUSIONS: Increasing septectomy does not improve irrigation delivery in patients undergoing EMLP. These results suggest that a limited septectomy for access to the bilateral frontal sinuses is all that is required for effective drug delivery postoperatively. This strategy may reduce morbidity associated with larger septectomies.
- Accessory maxillary ostium repair using middle turbinate flap: a case series of 116 patients with chronic rhinosinusitis. [Journal Article]
- IFInt Forum Allergy Rhinol 2018 Jun 08
- CONCLUSIONS: Repair of AMO is in theory a beneficial and technically feasible office procedure with only transient side effects. Three out of 4 perforations were closed after repair.
- A computed tomographic analysis of frontal recess cells in association with the development of frontal sinusitis. [Journal Article]
- ANAuris Nasus Larynx 2018 Jun 04
- CONCLUSIONS: The frontal recess cells variation in Malaysian subjects were almost similar to those reported in other Asian populations such as Japanese, Taiwanese, Chinese and Korean. Our study found that frontal bullar cells had a significant association with the development of frontal sinusitis than other frontal recess cells. The understanding of the frontal recess anatomical structures was very important as this would lead to a successful treatment of CRS and at the same time it helped the surgeon to have a better plan of endoscopic sinus surgery to prevent the disease recurrence and surgical complication.
- [Inflammatory myofibroblastic tumor of the paranasal sinus：three cases report]. [Case Reports]
- LCLin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2017 May 05; 31(9):722-724
- The clinical manifestations of paranasal sinusitis were similar to those of chronic sinusitis. The main manifestations were recurrent nasal congestion,nasal obstruction,such as invasion of the surrou...
The clinical manifestations of paranasal sinusitis were similar to those of chronic sinusitis. The main manifestations were recurrent nasal congestion,nasal obstruction,such as invasion of the surrounding tissue,local compression. Clinical manifestations were usually nonspecific. CT imaging could display the size,range of the tumor and its relationship with the surrounding tissues. Inflammatory myofibroblastic tumor is a low-grade malignant tumor and frequently misdiagnosed. Diagnosis depends on the pathological examination.Complete surgical resection is the preferred method of treatment. Adjuvant treatment included radiotherapy,chemotherapy and hormone therapy. recurrence and death was not uncommon.
- [The correlation between the types of the uncinate process superiorattachment and chronic frontal sinusitis without nasal polyps]. [Journal Article]
- LCLin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2017 May 05; 31(9):667-670
- Objective: To investigate the correlation between the types of unicate process (UP) superior attachment and the chronic frontal sinusitis without nasal polyps(CFSsNP).Method:The images of 240 sides o...
Objective: To investigate the correlation between the types of unicate process (UP) superior attachment and the chronic frontal sinusitis without nasal polyps(CFSsNP).Method:The images of 240 sides of frontal recess were evaluated. The types of UP superior attachment was compared between the CFSsNP group and the control group. The correlation between UP the superior attachment and CFSsNP were analyzed. Result:Seven types of UP superior attachment were identified. The most common type in the two study groups was type 1(insertion into the lamina papyracea). The occurrence rate of type 1 of UP superior attachment in the CFSsNP group was significantly higher than that in the control group(59.8% and 36.4%,respectively P<0.01),but type 5(insertion into both the lamina papyracea and the skull base) was significantly less frequent in the CFSsNP group than in the control group(9.8%，28.8%,P<0.01). Logistic regression analysis revealed that the type 1 of UP superior attachment was an independent risk factor for CFSsNP(OR=1.181,P<0.05),and that type 5 of UP superior attachment was a protective factor for CFSsNP(OR=0.391,P<0.05). Conclusion: UP superior attachment varied significantly,with the most common type being type 1; This type is intimately related to CFSsNP.
- Safety and Efficacy of Topical Chitogel- Deferiprone-Gallium Protoporphyrin in Sheep Model. [Journal Article]
- FMFront Microbiol 2018; 9:917
- Objectives: Increasing antimicrobial resistance has presented new challenges to the treatment of recalcitrant chronic rhinosinusitis fuelling a continuous search for novel antibiofilm agents. This s...
Objectives: Increasing antimicrobial resistance has presented new challenges to the treatment of recalcitrant chronic rhinosinusitis fuelling a continuous search for novel antibiofilm agents. This study aimed to assess the safety and efficacy of Chitogel (Chitogel®, Wellington New Zealand) combined with novel antibiofilm agents Deferiprone and Gallium Protoporphyrin (CG-DG) as a topical treatment against S. aureus biofilms in vivo. Methods: To assess safety, 8 sheep were divided into two groups of 7 day treatments (n = 8 sinuses per treatment); (1) Chitogel (CG) with twice daily saline flush, and (2) CG-DG gel with twice daily saline flush. Tissue morphology was analyzed using histology and scanning electron microscopy (SEM). To assess efficacy we used a S. aureus sheep sinusitis model. Fifteen sheep were divided into three groups of 7 day treatments (n = 10 sinuses per treatment); (1) twice daily saline flush (NT), (2) Chitogel (CG) with twice daily saline flush, and (3) CG-DG gel with twice daily saline flush. Biofilm biomass across all groups was compared using LIVE/DEAD BacLight stain and confocal scanning laser microscopy. Results: Safety study showed no cilia denudation on scanning electron microscopy and no change in sinus mucosa histopathology when comparing CG-DG to CG treated sheep. COMSTAT2 assessment of biofilm biomass showed a significant reduction in CG-DG treated sheep compared to NT controls. Conclusion: Results indicate that CG-DG is safe and effective against S. aureus biofilms in a sheep sinusitis model and could represent a viable treatment option in the clinical setting.
- Orbital Subcutaneous Emphysema in a Child. [Journal Article]
- JCJ Craniofac Surg 2018; 29(4):1020-1022
- The authors present a rare case of nontraumatic medial orbital wall fracture in an 11-year-old girl. Fractures of the orbital wall secondary to nose blowing have not been previously described in the ...
The authors present a rare case of nontraumatic medial orbital wall fracture in an 11-year-old girl. Fractures of the orbital wall secondary to nose blowing have not been previously described in the pediatric population. The patient reported a history of chronic forceful nose blowing, followed by periorbital swelling after an episode of vigorous nose blowing. Erroneous diagnoses of sinusitis and periorbital cellulitis lead to unnecessary antibiotic treatment. The authors hypothesize that repeated and aggressive nose blowing is analogous to stress fractures, leading to weakening and eventual fracture of the medial orbital wall.
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- The Utility of Polyether-Ether-Ketone Implants Adjacent to Sinus Cavities After Craniofacial Trauma. [Journal Article]
- JOJ Oral Maxillofac Surg 2018 May 10
- CONCLUSIONS: Literature review indicates that this is the largest case series reported to date documenting the use of PEEK implants in reconstruction of the region of the paranasal sinuses. Specific biologic, or alloplastic, barriers outside the formation of native scar tissue or regional fasciocutaneous tissues at the sites of reconstruction were not used in these reconstructions, although consideration for placement of these barriers can be at the discretion of the operative surgeon. The authors conclude that PEEK implants can be used in complex craniomaxillofacial reconstructive procedures to achieve near anatomic reconstruction not easily attainable through conventional means. Defects that involve the paranasal sinus cavities with a functional ostium or obliterated sinus cavity can be reconstructed with PEEK implants without increasing the risk of infection and need for explantation. Long-term follow-up and continued outcome results of this treatment modality will be necessary to verify its clinical usefulness in the future.