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(St John's wort)
3,319 results
  • Hypascyrins A-E, Prenylated Acylphloroglucinols from Hypericum ascyron. [Journal Article]
    J Nat Prod 2019Niwa K, Tanaka N, … Kashiwada Y
  • Six new prenylated acylphloroglucinols with menthane moieties, hypascyrins A-E (1-5) and ent-hyphenrone J (6), together with four known analogues, were isolated from Hypericum ascyron roots. Detailed spectroscopic data analyses resulted in the assignment of their structures. The absolute configuration of 1 was deduced by experimental and calculated ECD data, while those of 2-6 were assigned by EC…
  • Hyperoside exerts potent anticancer activity in skin cancer. [Journal Article]
    Front Biosci (Landmark Ed) 2020; 25:463-479Kong Y, Sun W, Wu P
  • Quercetin-3-O-β-D-galactopyranoside, is a hyperoside flavonol glycoside with anti-cancer, anti-inflammatory, and anti-oxidant activities that is derived from Hypericum and Crataegus plants. To this end, we examined the effect of this hyperoside in skin cancer cells lines and in DMBA/TPA induced skin tumors in vivo. In vitro treatment of cancer cells with hyperoside significantly inhibited phospho…
  • Cytotoxic Xanthones from Hypericum stellatum, an Ethnomedicine in Southwest China. [Journal Article]
    Molecules 2019; 24(19)Ji Y, Zhang R, … Long C
  • Hypericum stellatum, a species endemic to China, is used to treat hepatitis by several ethnic groups in Guizhou Province. This research was inspired by the traditional medicinal usage of H. stellatum, and aims to explore the phytochemistry and bioactivity of H. stellatum to explain why local people in Guizhou widely apply H. stellatum for liver protection. In this study, two new prenylated xantho…
  • Hypericum SPP.: An Update On The Biological Activities And Metabolic Profiles. [Journal Article]
    Mini Rev Med Chem 2019Marrelli M, Statti G, Conforti F
  • Plants from the genus Hypericum, one genera of the Hypericaceae family, have attracted a lot of attention for their potential pharmaceutical applications. Most of the studies in the literature focus on H. perforatum L. (common St. John's wort), whose complex spectrum of bioactive compounds makes this species one of the top herbal remedies and supplements in the world. It is also important to comp…
  • Soil Microbiomes Underlie Population Persistence of an Endangered Plant Species. [Journal Article]
    Am Nat 2019; 194(4):488-494David AS, Quintana-Ascencio PF, … Searcy CA
  • Microbiomes can dramatically alter individual plant performance, yet how these effects influence higher-order processes is not well resolved. In particular, little is known about how microbiome effects on individual plants alter plant population dynamics, a question critical to imperiled species conservation. Here we integrate bioassays, multidecadal demographic data, and integral projection mode…
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