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645 results
  • Mold inhalation causes innate immune activation, neural, cognitive and emotional dysfunction. [Journal Article]
    Brain Behav Immun 2019Harding CF, Pytte CL, … Abreu O
  • Individuals living or working in moldy buildings complain of a variety of health problems including pain, fatigue, increased anxiety, depression, and cognitive deficits. The ability of mold to cause such symptoms is controversial since no published research has examined the effects of controlled mold exposure on brain function or proposed a plausible mechanism of action. Patient symptoms followin…
  • Re-isolation and NMR Characterization of the Satratoxins G and H. [Letter]
    Magn Reson Chem 2019Hudson D, Singh AJ, … Hinkley SFR
  • The exquisitely cytotoxic macrolides, satratoxins G and H, have been re-isolated from a solvent extract of a rice culture inoculated with Stachybotrys chartarum to be used as high purity reference compounds for analytical analyses. Extensive chromatographic separation realized the compounds which were fully re-characterized in two solvents by 1D- and 2D-NMR spectroscopy, revealing some discrepanc…
  • Inhalation of Stachybotrys chartarum Fragments Induces Pulmonary Arterial Remodeling. [Journal Article]
    Am J Respir Cell Mol Biol 2019Croston TL, Lemons AR, … Beezhold DH
  • Stachybotrys chartarum is a fungal contaminant within the built environment and a respiratory health concern in the United States. The objective of this study was to characterize the mechanisms influencing pulmonary immune responses to repeatedly inhaled S. chartarum. Groups of B6C3F1/N mice repeatedly inhaled viable trichothecene-producing S. chartarum conidia (Strain A or Strain B), heat-inacti…
  • Decontamination of T-2 Toxin in Maize by Modified Montmorillonite Clay. [Journal Article]
    Toxins (Basel) 2019; 11(11)Olopade BK, Oranusi SU, … Njobeh PB
  • Montmorillonite clay has a wide range of applications, one of which includes the binding of mycotoxins in foods and feeds through adsorption. T-2 toxin, produced by some Fusarium, Myrothecium, and Stachybotrys species, causes dystrophy in the brain, heart, and kidney. Various formulations that include lemongrass essential oil-modified montmorillonite clay (LGEO-MMT), lemongrass powder (LGP), mont…
  • The Myth of Mycotoxins and Mold Injury. [Review]
    Clin Rev Allergy Immunol 2019; 57(3):449-455Chang C, Gershwin ME
  • In recent years, mold has been blamed for many symptoms or a constellation of symptoms. These symptoms are usually vague and subjective and difficult or impossible to measure or quantify. Moreover, there is no scientific evidence that mold has anything to do with these symptoms. In particular, the concept of toxic mold syndrome has permeated the public consciousness, and mycotoxins have falsely b…
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