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Did you mean: (Salvo 200)?
(Stalevo 200)
9 results
  • Determination of L-dopa, carbidopa, 3-O-methyldopa and entacapone in human plasma by HPLC-ED. [Journal Article]
    J Pharm Biomed Anal 2011; 54(3):562-7Bugamelli F, Marcheselli C, … Raggi MA
  • The aim of the study was the development of analytical methods suitable for the quantification of L-dopa, carbidopa and entacapone in plasma of Parkinsonian patients treated with Stalevo(®). The metabolite 3-O-methyldopa was also determined to obtain some indications on the pharmacokinetics of L-dopa. For the simultaneous analysis of L-dopa, 3-O-methyldopa and carbidopa, a RP C18 column as the st…
  • Levodopa/carbidopa/entacapone in Parkinson's disease. [Journal Article]
    Expert Rev Neurother 2009; 9(7):929-40Seeberger LC, Hauser RA
  • Levodopa is the most efficacious agent for the treatment of motor features of Parkinson's disease but its chronic use is associated with the development of motor complications. Mounting evidence indicates the short half-life of levodopa and resultant pulsatile stimulation of striatal dopamine receptors leads to wearing off, motor fluctuations and dyskinesias. Longer acting dopaminergic agents, su…
  • Levodopa/carbidopa/entacapone (Stalevo). [Clinical Trial]
    Neurology 2004; 62(1 Suppl 1):S64-71Hauser RA
  • A levodopa/carbidopa/entacapone combination product (Stalevo) was recently approved to treat patients with idiopathic Parkinson's disease (PD) who experience end-of-dose "wearing-off." Stalevo is available in dose combinations of levodopa/carbidopa/entacapone 50/12.5/200 mg (Stalevo 50), 100/25/200 mg (Stalevo 100), and 150/37.5/200 mg (Stalevo 150). A series of pharmacokinetic studies demonstrat…
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