- New serum biomarker identification and analysis by mass spectrometry in cervical precancerous lesion and acute cervicitis in South China. [Journal Article]
- CMCancer Manag Res 2019; 11:6151-6162
- CONCLUSIONS: By applying molecular markers to assess the progression of the disease, the accuracy and specificity of the diagnosis can be improved, which has certain prospects in clinical applications.
- Modeling and Selection of RF Thermal Plasma Hot-Wall Torch for Large-Scale Production of Nanopowders. [Journal Article]
- MMaterials (Basel) 2019 Jul 03; 12(13)
- Fouling is a great problem that significantly affects the continuous operation for large-scale radio-frequency (RF) thermal plasma synthesizing nanopowders. In order to eliminate or weaken the phenom…
Fouling is a great problem that significantly affects the continuous operation for large-scale radio-frequency (RF) thermal plasma synthesizing nanopowders. In order to eliminate or weaken the phenomenon, numerical simulations based on FLUENT software were founded to investigate the effect of operation parameters, including feeding style of central gas and sheath gas, on plasma torches. It is shown that the tangential feeding style of central gas brings serious negative axial velocity regions, which always forces the synthesized nanopowders to "back-mix", and further leads to the fouling of the quartz tube. Moreover, it is shown that sheath gas should be tangentially fed into the plasma reactor to further eliminate the gas stream's back-mixing. However, when this feeding style is applied, although the negative axial velocity region is decreased, the plasma gas and kinetic energy of the vapor phase near the wall of the plasma reactor are less and lower, respectively; as a result, that plasma flame is more difficult to be arced. A new plasma arcing method by way of feeding gun instead of torch wall was proposed and put in use. The fouling problem has been well solved and plasma arcing is well ensured, and as a result, the experiment on large-scale production of nanopowders can be carried out for 8 h without any interruption, and synthesized Si and Al2O3 nanopowders exhibit good dispersion and sphericity.
- Antimicrobial effects of microwave-induced plasma torch (MiniMIP) treatment on Candida albicans biofilms. [Journal Article]
- MBMicrob Biotechnol 2019 Jul 01
- The susceptibility of Candida albicans biofilms to a non-thermal plasma treatment has been investigated in terms of growth, survival and cell viability by a series of in vitro experiments. For differ…
The susceptibility of Candida albicans biofilms to a non-thermal plasma treatment has been investigated in terms of growth, survival and cell viability by a series of in vitro experiments. For different time periods, the C. albicans strain SC5314 was treated with a microwave-induced plasma torch (MiniMIP). The MiniMIP treatment had a strong effect (reduction factor (RF) = 2.97 after 50 s treatment) at a distance of 3 cm between the nozzle and the superior regions of the biofilms. In addition, a viability reduction of 77% after a 20 s plasma treatment and a metabolism reduction of 90% after a 40 s plasma treatment time were observed for C. albicans. After such a treatment, the biofilms revealed an altered morphology of their cells by atomic force microscopy (AFM). Additionally, fluorescence microscopy and confocal laser scanning microscopy (CLSM) analyses of plasma-treated biofilms showed that an inactivation of cells mainly appeared on the bottom side of the biofilms. Thus, the plasma inactivation of the overgrown surface reveals a new possibility to combat biofilms.
- Small head circumference at birth: an 8-year retrospective cohort study in China. [Journal Article]
- BPBMJ Paediatr Open 2019; 3(1):e000470
- CONCLUSIONS: Cantonese origin, exposure to teratogens, pre-eclampsia and TORCH infection may be risk factors for microcephaly. The high prevalence of relative microcephaly and associated poor outcomes suggests that high-risk women merit closer clinical management and follow-up to maximise fetal head development during pregnancy.
- Synthesis of ZnO Nanomaterials Using Low-Cost Compressed Air as Microwave Plasma Gas at Atmospheric Pressure. [Journal Article]
- NNanomaterials (Basel) 2019 Jun 28; 9(7)
- Zinc oxide (ZnO) nanomaterials were efficiently synthesized using a microwave plasma torch system at atmospheric pressure. The Zn powder was passed through a microwave plasma region, in which it melt…
Zinc oxide (ZnO) nanomaterials were efficiently synthesized using a microwave plasma torch system at atmospheric pressure. The Zn powder was passed through a microwave plasma region, in which it melted and vaporized. Tetrapod-type ZnO nanomaterials with a diameter of 29.8 ± 8.0 nm were synthesized using a high-purity O2/N2 mixed gas. In particular, ZnO nanowires with a diameter of 109.5 ± 8.0 nm and a length of 5-6 μm were produced using an inexpensive compressed air as a microwave plasma gas. It was confirmed that the nanowires synthesized using the compressed air showed higher light absorption in the visible region than the tetrapod-type ZnO. In addition, the redshifts in the absorption peak and photoluminescence peak were observed from 370.6 to 375.2 nm and 380 to 390 nm, respectively. The obtained results can be explained by the change of energy levels due to the defects in the ZnO nanowires such as vacancies and interstitials of Zn and oxygen. Finally, we can conclude that cost-effective compressed air is appropriate not only for the synthesis of ZnO nanowire, but also the enlargement of optical absorption and emission range.
- Arthur Every hands on the torch to new Editor-in-Chief of Ultrasonics. [Editorial]
- UUltrasonics 2019 May 24; :105935
- Carrying the torch: The life, work, and values of Basil A. Pruitt, Jr., MD, FACS, COL (ret), MC, USA. [Journal Article]
- JTJ Trauma Acute Care Surg 2019; 87(1S Suppl 1):S3-S9
- The Fetal Origins of Mental Illness. [Review]
- AJAm J Obstet Gynecol 2019 Jun 14
- The impact of infections and inflammation during pregnancy on the developing fetal brain remains incompletely defined with important clinical and research gaps. Though the classic infectious TORCH pa…
The impact of infections and inflammation during pregnancy on the developing fetal brain remains incompletely defined with important clinical and research gaps. Though the classic infectious TORCH pathogens [i.e. Toxoplasma gondii, rubella virus, cytomegalovirus (CMV), herpes simplex virus] are known to be directly teratogenic, emerging evidence suggests that these infections represent the most extreme end of a much larger spectrum of injury. We present the accumulating evidence that prenatal exposure to a wide variety of viral and bacterial infections - or simply inflammation - may subtly alter fetal brain development, leading to neuropsychiatric consequences for the child later in life. The link between influenza infections in pregnant women and an increased risk for development of schizophrenia in their children was first described more than 30 years ago. Since then, evidence suggests that a range of infections during pregnancy may also increase risk for autism spectrum disorder and depression in the child. Subsequent studies in animal models demonstrated that both pregnancy infections and inflammation can result in direct injury to neurons and neural progenitor cells or indirect injury through activation of microglia and astrocytes, which can trigger cytokine production and oxidative stress. Infectious exposures can also alter placental serotonin production, which can perturb neurotransmitter signaling in the developing brain. Clinically, detection of these subtle injuries to the fetal brain is difficult. As the neuropsychiatric impact of perinatal infections or inflammation may not be known for decades after birth, our construct for defining teratogenic infections in pregnancy (e.g. TORCH) based on congenital anomalies is insufficient to capture the full adverse impact on the child. We discuss the clinical implications of this body of evidence and how we might place greater emphasis on prevention of prenatal infections. For example, increasing uptake of the seasonal influenza vaccine is a key strategy to reduce perinatal infections and the risk for fetal brain injury. An important research gap exists in understanding how antibiotic therapy during pregnancy impacts the fetal inflammatory load and how to avoid inflammation-mediated injury to the fetal brain. In summary, we discuss the current evidence and mechanisms linking infections and inflammation with the increased lifelong risk of neuropsychiatric disorders in the child, and how we might improve prenatal care to protect the fetal brain.
- Genetic Diversity of Torch Ginger (Etlingera elatior) Germplasm Revealed by ISSR and SSR Markers. [Journal Article]
- BRBiomed Res Int 2019; 2019:5904804
- Fifty-seven accessions of torch ginger (Etlingera elatior) collected from seven states in Peninsular Malaysia were evaluated for their molecular characteristics using ISSR and SSR markers to assess t…
Fifty-seven accessions of torch ginger (Etlingera elatior) collected from seven states in Peninsular Malaysia were evaluated for their molecular characteristics using ISSR and SSR markers to assess the pattern of genetic diversity and association among the characteristics. Diversity study through molecular characterization showed that high variability existed among the 57 torch ginger accessions. ISSR and SSR molecular markers revealed the presence of high genetic variability among the torch ginger accessions. The combination of different molecular markers offered reliable and convincing information about the genetic diversity of torch ginger germplasm. This study found that SSR marker was more informative compared to ISSR marker in determination of gene diversity, polymorphic information content (PIC), and heterozygosity in this population. SSR also revealed high ability in evaluating diversity levels, genetic structure, and relationships of torch ginger due to their codominance and rich allelic diversity. High level of genetic diversity discovered by SSR markers showed the effectiveness of this marker to detect the polymorphism in this germplasm collection.
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- Long-term cost and utility consequences of short-term clinically important deterioration in patients with chronic obstructive pulmonary disease: results from the TORCH study. [Journal Article]
- IJInt J Chron Obstruct Pulmon Dis 2019; 14:939-951
- CONCLUSIONS: This study demonstrated that achieving early stability in COPD by preventing short-term CID is associated with better preservation of future QoL alongside reduced healthcare service costs.