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(The Cytochrome P450 System: What Is It and Why Should I Care )
3 results
  • Genetic predisposition to adverse drug reactions in the intensive care unit. [Review]
    Crit Care Med 2010; 38(6 Suppl):S106-16Empey PE
  • Adverse drug reactions are a significant public health problem that leads to mortality, hospital admissions, an increased length of stay, increasing healthcare costs, and withdrawal of drugs from market. Intensive care unit patients are particularly vulnerable and are at an elevated risk. Critical care practitioners, regulatory agencies, and the pharmaceutical industry aggressively seek biomarker…
  • Why there is no cookbook approach to palliative care: implications of the P450 enzyme system. [Review]
    Clin J Oncol Nurs 2003 Sep-Oct; 7(5):569-72Kuebler KK, Varga J, Mihelic RA
  • A plethora of literature describes the impact of the P450 enzyme system, but this information is limited regarding its relevancy to nursing practice. However, oncology nurses providing palliative symptom management must have a working knowledge of the P450 enzyme system to recognize the variability that exists among individual medication reactions or why a "cookbook approach" to symptom managemen…
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