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7,633 results
  • Thrombocytosis as a Marker for Postoperative Complications in Colorectal Surgery. [Journal Article]
  • GRGastroenterol Res Pract 2018; 2018:1978639
  • Mohamud M, Osborne L, … Chandrasekaran TV
  • CONCLUSIONS: In this retrospective study, thrombocytosis was shown to have a positive correlation with postoperative medical and surgical complications. An elevated platelet count in the postoperative period should alert the clinician to a developing complication. We recommend that further studies with a larger sample size would test the specific associations with individual complications.
  • [Cytopenia under topical imiquimod in two patients treated with oral hydroxyurea]. [Journal Article]
  • ADAnn Dermatol Venereol 2018 Sep 11
  • Joachim C, Gras-Champel V, … Carmi E
  • CONCLUSIONS: . The literature review identified reports of dose-dependent lymphopenia under oral imiquimod but not under Aldara®. The National Pharmacovigilance Database listed 10 cases of hematological disorders most likely caused by Aldara®. Hydroxyurea may induce cytopenia, and while it was not considered the sole causative agent in this case, it is likely to have had a triggering role in these patients with blood dyscrasias. Our findings show that misuse of imiquimod carries a potential risk of hematologic abnormality in patients receiving concomitant hydroxyurea, a commonly combined drug.
  • The Platelet Count and its Implications in Sickle Cell Disease Patients Admitted for Intensive Care. [Journal Article]
  • IJIndian J Crit Care Med 2018; 22(8):585-590
  • Shome DK, Jaradat A, … Azeez Pasha SA
  • CONCLUSIONS: In severe sickle cell crisis thrombocytopenia is more common than thrombocytosis. In the ICU, day 1 platelet counts correlate inversely with prognostic scores and are significantly reduced in multi-organ failure and nonsurvivors. A platelet count above 175 × 109/L predicts patient survival with high specificity and positive predictive value but lacks sensitivity.
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