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(Transverse Myelitis AND ("Novel Coronavirus" OR COVID-19 OR SARS-CoV-2 OR 2019-nCoV))
91 results
  • Post-COVID Neuromyelitis Optica Spectrum Disorder. [Case Reports]
    J Coll Physicians Surg Pak. 2021 07; 31(7):138-140.Rafique S, Wasim A, … Ahmad A
  • After novel coronavirus pandemic that emerged from Wuhan, China in December 2019, several cases of inflammatory and immune-mediated disorders have been reported, thought to be triggered by SARS-CoV-2 infection. Neuromyelitis optica spectrum disorder (NMOSD) is one of the autoimmune demyelinating disorders, which is thought to be triggered by viral infection. Herein, we describe a case of NMOSD in…
    Wiad Lek. 2021; 74(4):1045-1049.Palahuta HV, Fartushna OY, … Hnepa YY
  • We aim to report a COVID-19-related case of acute myelitis that has not been associated with any other viral infections. A 23-year-old student was admitted to the hospital within a month from the time of loss of smell and taste with features of acute-onset non-compressive myelitis with paresthesia on both sides from the Th9 level. Complex neurological, clinical, laboratory, and neuroimaging exami…
  • MRI negative myelopathy post mild SARS-CoV-2 infection: vasculopathy or inflammatory myelitis? [Journal Article]
    J Neurovirol. 2021 Jun 08 [Online ahead of print]Abrams RMC, Safavi F, … Shin SC
  • Since the onset of the COVID-19 pandemic, there have been rare reports of spinal cord pathology diagnosed as inflammatory myelopathy and suspected spinal cord ischemia after SARS-CoV-2 infection. Herein, we report five cases of clinical myelopathy and myeloradiculopathy in the setting of post-COVID-19 disease, which were all radiographically negative. Unlike prior reports which typically characte…
  • Neurological complications in pediatric patients with SARS-CoV-2 infection: a systematic review of the literature. [Journal Article]
    Ital J Pediatr. 2021 Jun 02; 47(1):123.Siracusa L, Cascio A, … Colomba C
  • CONCLUSIONS: Our research highlights the large range of neurological manifestations and their presumed pathogenic pathways associated with SARS-CoV-2 infection in children. Nervous system involvement could be isolated, developing during COVID-19 or after its recovery, or arise in the context of a MIS-C. The most reported neurological manifestations are cerebrovascular accidents, reversible splenial lesions, GBS, benign intracranial hypertension, meningoencephalitis; ADEM is also a possible complication, as we observed in our patient. Further studies are required to investigate all the neurological complications of SARS-CoV-2 infection and their underlying pathogenic mechanism.
  • Systematic review of cases of acute myelitis in individuals with COVID-19. [Journal Article]
    Eur J Neurol. 2021 Jun 01 [Online ahead of print]Schulte EC, Hauer L, … Sellner J
  • CONCLUSIONS: Although causality cannot readily be inferred, it is possible that cases of ATM occur para- or post-infectiously in COVID-19. All identified reports are anecdotal and case descriptions are heterogeneous. Whether the condition and the observed radiological characteristics are specific to SARS-CoV-2 infection needs to be clarified.
  • Acute Transverse Myelitis (ATM):Clinical Review of 43 Patients With COVID-19-Associated ATM and 3 Post-Vaccination ATM Serious Adverse Events With the ChAdOx1 nCoV-19 Vaccine (AZD1222). [Case Reports]
    Front Immunol. 2021; 12:653786.Román GC, Gracia F, … Harris D
  • CONCLUSIONS: We found ATM to be an unexpectedly frequent neurological complication of COVID-19. Most cases (68%) had a latency of 10 days to 6 weeks that may indicate post-infectious neurological complications mediated by the host's response to the virus. In 32% a brief latency (15 hours to 5 days) suggested a direct neurotropic effect of SARS-CoV-2. The occurrence of 3 reported ATM adverse effects among 11,636 participants in the AZD1222 vaccine trials is extremely high considering a worldwide incidence of 0.5/million COVID-19-associated ATM cases found in this report. The pathogenesis of ATM remains unknown, but it is conceivable that SARS-CoV-2 antigens -perhaps also present in the AZD1222 COVID-19 vaccine or its chimpanzee adenovirus adjuvant- may induce immune mechanisms leading to the myelitis.
  • Myelopathy associated with SARS-COV-2 infection. A systematic review. [Journal Article]
    Neurol Res. 2021 Apr 17 [Online ahead of print]Artemiadis A, Liampas A, … Zis P
  • Background׃COVID-19 (CoranaVirus disease 2019) is an ongoing infectious disease caused by the RNA SARS-CoV-2 virus (Severe Acute Respiratory Syndrome CoronaVirus-2). More than one-third of COVID-19 patients report neurological symptoms and cases of neurological diseases are increasingly accumulating. The aim of this systematic review was to characterize all - to date - reported cases with COVID-1…
  • Cervical spinal cord infarction associated with coronavirus infectious disease (COVID)-19. [Case Reports]
    J Clin Neurosci. 2021 May; 87:89-91.Kahan J, Gibson CJ, … Segal AZ
  • Coronavirus disease (COVID-19) has a number of emerging neurological manifestations in addition to pneumonia and respiratory distress. In what follows, we describe a case of a previously healthy young man with severe COVID-19 who subsequently developed an acute flaccid paralysis. Work up revealed a lesion in his cervical spinal cord concerning for spinal infarction or transverse myelitis. He rece…
  • Post-COVID-19 encephalomyelitis. [Letter]
    Neurol Res Pract. 2021 Mar 15; 3(1):18.Kim JW, Abdullayev N, … Lehmann HC
  • Since the outbreak of coronavirus disease 2019 (COVID-19), a growing number of cases of acute transverse myelitis associated with COVID-19 have been reported. Here, we present the case of a patient who developed sensory ataxia after COVID-19 with MR lesions suggestive for longitudinal myelitis and in the splenium of the corpus callosum. The patient was successfully treated with immunoadsorption.
  • Spinal cord involvement in COVID-19: A review. [Journal Article]
    J Spinal Cord Med. 2021 Mar 11 [Online ahead of print]Garg RK, Paliwal VK, Gupta A
  • CONCLUSIONS: A variety of COVID-19-related spinal cord manifestations, such as acute transverse myelitis, acute necrotizing myelitis, SARS-CoV-2 myelitis, acute disseminated encephalomyelitis, neuromyelitis optica spectrum disorder, hypoxic myelopathy, MOG antibody-associated myelitis, spinal cord infarction, and spinal epidural abscess, have been reported. The possible mechanisms of this involvement being direct invasion, cytokine storm, coagulopathy, and an autoimmune response. However, response to treatment has been generally unsatisfactory, with many patients having residual weakness necessitating long-term rehabilitation.
  • COVID-19, HHV6 and MOG antibody: A perfect storm. [Case Reports]
    J Neuroimmunol. 2021 04 15; 353:577521.Jumah M, Rahman F, … Abboud H
  • CONCLUSIONS: Patients with neurological manifestations in the setting of COVID19-related immunodeficiency should be tested for opportunistic infections including HHV6. Viral infection is a known trigger for MOG-IgG and therefore this antibody should be checked in patients with SARS-CoV-2 associated demyelination.
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