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(Upper Respiratory Infection)
366,842 results
  • Respiratory syncytial virus nonstructural proteins 1 and 2: Exceptional disrupters of innate immune responses. [Review]
    PLoS Pathog 2019; 15(10):e1007984Sedeyn K, Schepens B, Saelens X
  • Human respiratory syncytial virus (RSV) is the most important cause of acute lower respiratory tract disease in infants worldwide. As a first line of defense against respiratory infections, innate immune responses, including the production of type I and III interferons (IFNs), play an important role. Upon infection with RSV, multiple pattern recognition receptors (PRRs) can recognize RSV-derived …
  • Viral respiratory infections and the oropharyngeal bacterial microbiota in acutely wheezing children. [Journal Article]
    PLoS One 2019; 14(10):e0223990Cuthbertson L, Oo SWC, … Cookson WOC
  • Acute viral wheeze in children is a major cause of hospitalisation and a major risk factor for the development of asthma. However, the role of the respiratory tract microbiome in the development of acute wheeze is unclear. To investigate whether severe wheezing episodes in children are associated with bacterial dysbiosis in the respiratory tract, oropharyngeal swabs were collected from 109 childr…
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