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(Upper respiratory tract infection upper respiratory infection )
441,752 results
  • Sputum Susceptibilities in a Nationwide Veteran Cohort. [Journal Article]
    Am J Infect Control. 2021 Mar 01 [Online ahead of print]Moore R, Wattengel BA, … Mergenhagen KA
  • CONCLUSIONS: The antibiogram of sputum isolates from the VA Healthcare System were examined to determine changes in patterns of resistance over a decade of use.This large-scale study investigated nationwide sputum culture susceptibility trends. Avoidance of macrolides for empiric treatment of community acquired pneumonia and avoidance of fluoroquinolones for empiric treatment of hospital acquired or ventilator associated pneumonia may be warranted based on susceptibility trends.
  • Specific Susceptibility to COVID-19 in Adults with Down Syndrome. [Journal Article]
    Neuromolecular Med. 2021 Mar 04 [Online ahead of print]Illouz T, Biragyn A, … Okun E
  • The current SARS-CoV-2 outbreak, which causes COVID-19, is particularly devastating for individuals with chronic medical conditions, in particular those with Down Syndrome (DS) who often exhibit a higher prevalence of respiratory tract infections, immune dysregulation and potential complications. The incidence of Alzheimer's disease (AD) is much higher in DS than in the general population, possib…
  • Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies. [Journal Article]
    Cell Host Microbe. 2021 Feb 25 [Online ahead of print]Zhou D, Chan JF, … Chen Z
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is characterized by a burst in the upper respiratory portal for high transmissibility. To determine human neutralizing antibodies (HuNAbs) for entry protection, we tested three potent HuNAbs (IC50 range, 0.0007-0.35 μg/mL) against live SARS-CoV-2 infection in the golden Syrian hamster model. These HuNAbs inhibit SARS-CoV-2 infection by …
  • The Future of Respiratory Syncytial Virus Disease Prevention and Treatment. [Review]
    Infect Dis Ther. 2021 Mar 03 [Online ahead of print]Domachowske JB, Anderson EJ, Goldstein M
  • Respiratory syncytial virus (RSV) is a major cause of respiratory tract infections in infants, young children, and older or immunocompromised adults. Although aerosolized ribavirin was licensed for RSV treatment on the basis of data demonstrating a reduced need for supplemental oxygen, ribavirin use is limited because of issues with efficacy, safety, and cost. Currently, the treatment of RSV is p…
  • Socioeconomic Impact of RSV Hospitalization. [Review]
    Infect Dis Ther. 2021 Mar 03 [Online ahead of print]Young M, Smitherman L
  • Respiratory syncytial virus (RSV) disease is a significant cause of morbidity and socioeconomic burden worldwide among young children. The majority of RSV-associated lower respiratory tract infections (LRTI) and mortality occurs in developing countries and is associated with various sociodemographic risk factors. Independent risk factors for severe RSV disease include age and premature birth. Whi…
  • Klebsiella oxytoca and Emerging Nosocomial Infections. [Review]
    Curr Microbiol. 2021 Mar 03 [Online ahead of print]Neog N, Phukan U, … Chetia P
  • Klebsiella oxytoca is rising as a significant opportunistic pathogen causing nosocomial infections in neonates as well as adults. This pathogen's prevalence varies from 2 to 24%, but outbreaks of infections due to multidrug-resistant strains can be fatal in immunocompromised individuals with comorbidities. Klebsiella oxytoca is responsible for a wide range of ailments from colitis to infective en…
  • [COVID-19 and myocardial injury]. [Journal Article]
    Rev Med Suisse. 2021 Mar 03; 17(728):418-423.Schukraft S, Puricel S, … Arroyo D
  • SARS-CoV-2 affects the cardiovascular system triggering a proinflammatory response which results in direct and indirect myocardial injury. The objective of this article is to describe the underlying mechanisms and clinical implications.
  • Differential proteomic analysis of children infected with respiratory syncytial virus. [Journal Article]
    Braz J Med Biol Res. 2021; 54(4):e9850.Yin GQ, Zeng HX, … Cai SX
  • Respiratory syncytial virus (RSV) infection is the main cause of lower respiratory tract infection in children. However, there is no effective treatment for RSV infection. Here, we aimed to identify potential biomarkers to aid in the treatment of RSV infection. Children in the acute and convalescence phases of RSV infection were recruited and proteomic analysis was performed to identify different…
  • The year's new drugs and biologics 2020. [Journal Article]
    Drugs Today (Barc). 2021 Feb; 57(2):101-177.Graul AI, Sorbera LA
  • 2020 will go down in history as a year marked in every respect by the emergence and astonishingly rapid spread of the first major global viral pandemic in a century. It seems like nearly every event or story of the year was influenced in some way by COVID-19, and in that respect, the year ended on a high note with the authorization for emergency use of the first vaccines to prevent SARS-CoV-2 inf…
  • [CME/Answers: Hypertension and the COVID-19 Pandemic: What to Consider in Medical Practice]. [Journal Article]
    Praxis (Bern 1994). 2021; 110(3):141-142.Wuerzner G, Waeber B
  • CME/Answers: Hypertension and the COVID-19 Pandemic: What to Consider in Medical Practice Abstract. The COVID-19 pandemic represents a major public health problem. A fraction of the population is at increased risk of developing complications of this disease, in particular older subjects as well as diabetic, obese and hypertensive patients. With regard to patients with high blood pressure, the exi…
  • [CME/Answers: Hypertension and the COVID-19 Pandemic: What to Consider in Medical Practice]. [Journal Article]
    Praxis (Bern 1994). 2021; 110(3):1-2.Wuerzner G, Waeber B
  • CME/Answers: Hypertension and the COVID-19 Pandemic: What to Consider in Medical Practice Abstract. The COVID-19 pandemic represents a major public health problem. A fraction of the population is at increased risk of developing complications of this disease, in particular older subjects as well as diabetic, obese and hypertensive patients. With regard to patients with high blood pressure, the exi…
  • Diabetes in America: Infections Associated With Diabetes [BOOK]
    Diabetes in America. National Institute of Diabetes and Digestive and Kidney Diseases (US): Bethesda (MD)Cowie CC, Casagrande SS, … Fradkin JEEgede LE, Hull BJ, … Williams JSBOOK
  • Evidence supporting the notion that diabetes predisposes to an increased risk of infection continues to be inconclusive. In fact, in patients with diabetes, the percentage of outpatient visits to a physician because of an infection ranges from 1.6% to 5.1%, whereas individuals without diabetes average 2.6%–3.6% outpatient visits to physicians as a result of an infection. Additionally, compared to…
  • "Lock-down'' for COVID-19 has ''locked up'' Urological emergencies in Greece. [Journal Article]
    Arch Esp Urol. 2021 Mar; 74(2):183-184.Lazaros L, Tzelves L, … Varkarakis I
  • Over the last couple of months physicians world wide are struggling to prevent the novel coronavirus (COVID-19) spread all over the world. It has become obvious that our health care systems should under go modifications in order to successfully confront similar pandemics, since this is considered the ''century of pandemics'', due to the high incidence of new virus attacks with expressly high viru…
  • Therapeutic activity of an inhaled potent SARS-CoV-2 neutralizing human monoclonal antibody in hamsters. [Journal Article]
    Cell Rep Med. 2021 Feb 25 [Online ahead of print]Piepenbrink MS, Park JG, … Kobie JJ
  • SARS-CoV-2 infection results in viral burden in the respiratory tract, enabling transmission and leading to substantial lung pathology. The 1212C2 fully human monoclonal antibody was derived from an IgM memory B cell of a COVID-19 patient, has high affinity for the Spike protein Receptor Binding Domain, neutralizes SARS-CoV-2 and exhibits in vivo prophylactic and therapeutic activity in hamsters …
  • Guillain-Barré syndrome. [Review]
    Lancet. 2021 Feb 26 [Online ahead of print]Shahrizaila N, Lehmann HC, Kuwabara S
  • Guillain-Barré syndrome is the most common cause of acute flaccid paralysis worldwide. Most patients present with an antecedent illness, most commonly upper respiratory tract infection, before the onset of progressive motor weakness. Several microorganisms have been associated with Guillain-Barré syndrome, most notably Campylobacter jejuni, Zika virus, and in 2020, the severe acute respiratory sy…
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